A5002940931- Natural product bioactivities and synthesis
- Phytochemistry and Biological Activities
- Essential Oils and Antimicrobial Activity
- Phytochemical compounds biological activities
- Phytochemicals and Antioxidant Activities
- Sesquiterpenes and Asteraceae Studies
- Biological Activity of Diterpenoids and Biflavonoids
- Bee Products Chemical Analysis
- Plant biochemistry and biosynthesis
- Toxin Mechanisms and Immunotoxins
- Plant Toxicity and Pharmacological Properties
- Phytoestrogen effects and research
- Wastewater Treatment and Nitrogen Removal
- Insect and Pesticide Research
- Phytochemistry Medicinal Plant Applications
- Nuts composition and effects
- biodegradable polymer synthesis and properties
- Genomics and Phylogenetic Studies
- Molecular Sensors and Ion Detection
- Seed and Plant Biochemistry
- Lichen and fungal ecology
- Nanoplatforms for cancer theranostics
- Traditional and Medicinal Uses of Annonaceae
- Peanut Plant Research Studies
- Microbial Fuel Cells and Bioremediation
Ege University
2015-2024
Boğaziçi University
2017
Karlsruhe Institute of Technology
2011
The Gram-negative marine bacterium Photobacterium damselae subsp. piscicida (Pdp) is a pathogen responsible for pseudotuberculosis in various fish species, posing significant threats to aquaculture. Pdp employs strong virulence mechanisms, one of which the production piscibactin siderophore, plays key role iron acquisition from host. In this study, we evaluated ferrophilic properties strain EKL1 relation growth and biofilm production. vitro limitation significantly suppressed formation...
Five new oleanane-type triterpenoid glycosides (1-5), named scoposides A-E, along with one known bisdesmosidic triterpene glycoside, were isolated from the aerial parts of Cephalaria scoparia. Three prosapogenins (2a-4a) also obtained after alkaline hydrolysis compounds 2-4. The structures 1-5 determined by spectroscopic (1D and 2D NMR, HRESIMS) chemical methods. antimicrobial effects evaluated against a small panel Gram-positive Gram-negative bacteria.
A phytochemical investigation of the aerial parts <i>Cephalaria elmaliensis</i> resulted in isolation ten hederagenin-type triterpene saponins (<b>1</b>–<b>10</b>) including three new ones, elmalienoside (<b>1</b>), B (<b>2</b>), C (<b>3</b>), and two known flavonoid glycosides (<b>11</b>–<b>12</b>). Their structures were identified by extensive spectroscopic techniques (1D 2D NMR, HR ESIMS) chemical evidence. The antimicrobial activity extracts pure compounds was evaluated MIC method....
There are nearly 1200 species of sea cucumber in the world's seas.Among these creatures included Holothuroidea class, 37 show distribution Mediterranean and Aegean Sea.The purpose this study is to determine chemical content biological potent five species, Holothuria tubulosa, poli, mammata, sanctori Stichopus regalis which were collected from detailed flavonoid, phenolic triterpene contents determined by LC-HR/MS.Cytotoxic activities against several cancer cell lines, MDA-MB-231, PC-3, A549,...
Polymeric micellar systems are emerging as a very important class of nanopharmaceuticals due to their ability improve pharmacokinetics and biodistribution chemotherapy drugs, well reduce related systemic toxicities. While these nanosized delivery inherently benefit from passive targeting through the enhanced permeation retention effect leading increased accumulation in tumor, additional active can be achieved surface modification micelles with groups specific for overexpressed receptors...
Abstract The hexane extracts of eight Cephalaria (Dipsacaceae) species, which were collected from southwestern Anatolia, obtained by Soxhlet apparatus. fatty acids derived to methyl esters and determined gas chromatography/flame ionization detector (GC/FID) chromatography/mass spectrometry (GC/MS) systems. dominant acid components maximum percentages detected as myristic [in C. joppica (17.48 %)], palmitic cilicica , elmaliensis isaurica scoparia (19.51 %), gazipashaensis ], linoleic (33.02...
Propolis is a valuable natural substance obtained by honey bees after being collected from the bark, resin of trees, plant leaves and mixed with their saliva, has been widely used for various biological activities. The properties propolis can vary botanical origin, location hives colony population. It thought that color one main factors determining its acceptability originates flower markers, pollen nectar some plants directly related to chemical content. important compare standardize...
This study determined the effects of different doses biochars (B) on Virginia tobacco (Nicotiana tabacum L.) cultivar, first and second harvest dependent change in plant nutrients (N, P, K, Ca, Mg, Cl, Zn, Fe, Mn, Cu, B), leaf color parameters (L*, a*, b*), chlorophyll value (SPAD), electrolyte leakage (EL), crude ash, number leaves, height. Pot experiments were conducted with biochar treatments 10 tons ha−1 (B1), 20 (B2), 40 (B3), 80 (B4). Tobacco macroelement Mg) levels increased...
Saponins are glycosides widely distributed in the plant kingdom and have many pharmacological activities. However, their tendency to bind cell membranes can cause rupture, limiting clinical use. In previous study, aristatoside C davisianoside B were isolated from Cephalaria species. Cytotoxicity assays showed that they more active on A-549 lines than doxorubicin but caused hemolysis. current research, loaded phytosomes called ALPs DLPs respectively, characterized for particle size, zeta...
The removal of various phenoxyalkanoic acid herbicides as single solutes (2,4-D; 2,4-DP; 2,4-DB; 2,4,5-T; MCPA) from aqueous solutions were studied by using biodegradable poly(ε-caprolactone) (PCL). A comparative study was achieved powdered and granular activated carbon an adsorbent in a batch system. equilibrium at 25, 35, 45°C. results correlated Freundlich Langmuir, Temkin, Redlich-Peterson, Sips equations. To determine the best fit isotherm, three error analysis methods used to evaluate...
A new hederagenin-type triterpene saponin; hederagenin 28-O-β-D-galactopyranosyl-(1→6)-β-D-glucopyranosyl ester named sumbulianoside (1), together with twelve known saponins were isolated from the n-butanol extract of Cephalaria sumbuliana (Caprifoliaceae) which, one saponin, dipsacus saponin (2) was isolated, for first time species. The structures compounds elucidated by 1 D and 2 NMR HRESIMS analyses. Cytotoxic activities investigated on A549, Hela, PANC1, SHSY5Y cells non-cancerous cell...
Abstract Two flavonoid glycosides (compounds 1 and 3) of which one is reported for the first time a methylinositol (compound 2) were isolated from aerial parts Ebenus haussknechtii (Leguminosae). The structures established as quercetin-7-O-[α-L-rhamnopyranosyl(1 → 6)-β-D-galactopyranoside] (1), morin-3-O-[4-[5-(4-hydroxyphenyl)pentanoyl]-α-L-rhamnopyranosyl(1 6)-β-D-galactopyranosyl]-7-4′-di-O-methyleter (3), (2) on basis chemical spectroscopic means. antimicrobial activities extracts have...
Justin Kamgaab, Louis P. Sandjoa*, Nazli Böke-Sarikahyab, Süheyla Kirmizigülb*, Victor Kuetec & Bonaventure T. Ngadjuiada Department of Organic Chemistry, Faculty Sciences, University Yaoundé I, P.O. Box 812, Yaoundé, Cameroonb Section Science, Ege University, 35500 Bornova-Izmir, Turkeyc Biochemistry, Dschang, Cameroond Pharmaceutical Sciences and Traditional Pharmacopeia, Medicine Biomedical 8664, Cameroon