A5012616332- Drug Solubulity and Delivery Systems
- Advanced Drug Delivery Systems
- Analytical Methods in Pharmaceuticals
- Advancements in Transdermal Drug Delivery
- Protein purification and stability
- Nanoparticle-Based Drug Delivery
- Coral and Marine Ecosystems Studies
- Protein Interaction Studies and Fluorescence Analysis
- Lung Cancer Treatments and Mutations
- Synthesis and biological activity
- Cancer therapeutics and mechanisms
- Dermatology and Skin Diseases
- Radiomics and Machine Learning in Medical Imaging
- Marine Sponges and Natural Products
- Amoebic Infections and Treatments
- Graphene and Nanomaterials Applications
- Phytochemicals and Medicinal Plants
- Multiple Myeloma Research and Treatments
- Oral and gingival health research
- Pesticide Residue Analysis and Safety
- Corneal Surgery and Treatments
- Thyroid Disorders and Treatments
- Synthesis and Biological Evaluation
- Otolaryngology and Infectious Diseases
- Fibroblast Growth Factor Research
Parul University
2018-2024
University of Maryland, Baltimore
2024
Koneru Lakshmaiah Education Foundation
2023
Devi Ahilya Vishwavidyalaya
2020-2022
Sigma (Poland)
2019
CU Shah Medical College and Hospital
2015
National Institute of Pharmaceutical Education and Research
2007
Smart polymers have enormous potential in various applications. In particular, smartpolymeric drug delivery systems been explored as “intelligent” able to :release, at the appropriate time and site of action, entrapped drugs response specific physiological triggers. These exhibit a non-linear small stimulus leading macroscopic alteration their structure/properties. polymers, also known stimuli-responsive are an emerging class materials designed respond dynamically external stimuli such...
The current research was undertaken to design stealth liposomes of 5-Fluorouracil for reducing its cardiotoxicity and prolong the half-life by developing long-circulating liposomes. were prepared NH4EDTA gradient method, where EDTA is used as a cardioprotectant. Ascorbyl-6-palmitate also which helped synergistic effect counteract cancer cells provide promising application in treatment breast cells. Taguchi screening formulation HSPC phospholipid selected. drug-excipient compatibility checked...
Present investigation was aimed to develop aspasomal gel of Mometasone Furoate for the treatment Psoriasis that are biologically active and deliver drug at controlled rate decrease dosing frequency.The vesicles were fabricated using film hydration method optimized 32 factorial Design. Prepared formulations evaluated percent loading, vesicle size, Zeta potential, polydispersity index morphological studies. Gel prepared carbopol by loading loaded asposomes content, pH, viscosity spreadability....
24May 2018 TRANSDERMAL DRUG DELIVERY SYSTEMS: A MINI REVIEW. Rakesh Patel , Ankita Bijal Prajapati Gajanan Shinde and Abhay Dharamsi. Faculty of Pharmacy, Parul Institute University, Vadodara -391760, Gujarat, India. Mil Laboratories Pvt. Ltd., Manjusar GIDC, Plot no ? 541-542 Taluka- Savali, Gujarat.
The traditional system of medicine requires intensive investigation in quality control tocompete with the modern globally. present research work on developmentand standardization poly herbal capsule formulation which consist Ocimum sanctum,Curcuma longa, Emblica officinalis, Teriminalia bellerica, chebula, Piper longum,Piper nigrum, and Zingiber officinale. parameters such as organolepticevaluation, powder microscopic analysis poly-herbal crude drugs material physicalproperty bulk density,...
This paper provides an overview of enhanced properties nanofluids which are used in plethora engineering applications ranging from use automotive industry to medical arena power plant cooling systems. In addition , it also highlights future work and possibilities. The novel concept the spring 1993, talented studious thermal scientists engineers rapidly growing community have made scientific breakthrough not only discovering unexpected but proposing new mechanisms behind nanofluids. As a...
mTORC1/ PI3K control multiple anabolic pathways, including protein synthesis, ribosome production, lipogenesis, and nucleotide are all important for cell tissue growth. Sapanisertib Dactolisib inhibit PI3K/AKT/mTOR pathway, an signaling pathway many cellular functions such as growth control, metabolism translation initiation.Dactolisib contains quinolin-3-yl-2,3-dihydroimidazo[4,5-c]quinolin scaffold benzo[d]oxazol-5-yl-1-ethyl-1H-pyrazolo[3,4-d]pyrimidinnucleous. From the reference to both...
Voriconazole is an effective antifungal drug, used as first line treatment for Invasive Aspergillosis. The present work focusses on formulation of PEGylated liposomes to achieve longer circulation in the blood, prevent from opsonisation by mononuclear phagocytic system RES. higher plasma concentration voriconazole leads visual disturbance and dermatological side effect, which are minimized PEGylation. Compatibility studies like FTIR (Fourier Transform IR) DSC (Differential Scanning...
Background: A drug package insert or prescribing information is a document provided along with prescription medication to provide additional about that drug. Drug inserts are approved by the administrative licensing authority. intended for safe and effective use of respective Product pharmaceutical companies has been determined be far from adequate not conforming requirement Indian regulatory. Hence, it was decided conduct study assess presentation completeness clinically important in...
Background: The current research aimed to create and analyze a new long-acting Brexpiprazole (BRX) injectable for successful anti-psychotic drug therapy in order decrease dosage frequency increase patient compliance. Systems transport particular body sites or regulating release rates with accuracy are known as delivery systems (DDS). By affixing the carrier particle like liposomes, nanoparticles, microspheres, etc., which modifies drug's absorption properties, using technology, drugs may be...
Introduction/Objective: Microneedle technology has emerged as a promising approach for drug delivery, offering advantages such improved patient compliance and enhanced therapeutic efficacy. This review aims to provide comprehensive overview of recent advancements in microneedle- based delivery systems, emphasizing their potential overcome limitations associated with traditional transdermal methods. The objective is synthesize existing knowledge, identify key trends, highlight applications...
In present research article, we reported the synthesise of novel hetertocyclic ligand namely,5-((3-((1H-benzimidazol-1-yl)methyl)-5-phenyl-1H-pyrazol-1-yl) methyl)-8-hydroxy quinoline (BIPPHQ) from 5-chloro methyl-8-hydroxy and 1-((5-phenyl-1H-pyrazol-3-yl) methyl)-1H-benzimidazole (BIPP). The BIPP was synthsised by reaction between hydrazine hydrate with 1-(1H-benzimidazol-1-yl)-4-phenylbut-3-en-2-one (BIPB), which synthesisd 1-(1H-benzimidazol-1-yl)propan-2-one (BIP) benzaldehyde....
The aim of the present study was to formulate and develop Nanoparticulate drug delivery system (Nanostructured Lipid Carrier) for treatment Acne. nanostructured lipid carrier prepared by high speed pressure homogenizer using different types solid lipid, liquid concentration surfactants. NLC characterized particle size, zeta potential, polydispersity index. Stearic acid oleic were used as Pluronic F-68 surfactant. excipient compatibility performed Fourier transform infrared spectrophotometer...
This article highlights major scientific outcomes of the studies carried out using Airborne Visible/Infrared Imaging Spectrometer-Next Generation (AVIRIS-NG) airborne data over coastal regions Mangaluru, Gulf Kachchh (GoK) and Chilika lagoon.Various hyperspectral remote sensing techniques involving bio-optical models spectral classification algorithms are used to achieve different objectives related ecosystem monitoring.AVIRIS-NG estimate particle size suspended solids along waters Mangaluru...
The purpose of the study was to develop and evaluate mucoadhesive microspheres Mometasone for pulmonary drug delivery system having prolonged residence time sustained release. Microspheres were prepared by emulsification solvent evaporation technique using HPMC, carbopol as polymers in varying ratios. evaluated its percentage yield, entrapment efficiency, particle size shape, In vitro mucoadhesion release studies. FTIR studies revealed no chemical interaction between molecule found that...