Francesca Rotondo

ORCID: 0000-0002-8208-3967
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About
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Research Areas
  • Plant Pathogens and Fungal Diseases
  • Plant-Microbe Interactions and Immunity
  • Plant Pathogenic Bacteria Studies
  • Carcinogens and Genotoxicity Assessment
  • Wheat and Barley Genetics and Pathology
  • Plant Disease Resistance and Genetics
  • Plant Pathogens and Resistance
  • Fungal Plant Pathogen Control
  • Genetics and Plant Breeding
  • Genetic Mapping and Diversity in Plants and Animals
  • Effects and risks of endocrine disrupting chemicals
  • Crop Yield and Soil Fertility
  • Toxic Organic Pollutants Impact
  • Air Quality and Health Impacts
  • Plant Virus Research Studies
  • Mycotoxins in Agriculture and Food
  • Molecular Biology Techniques and Applications
  • Computational Drug Discovery Methods
  • Legume Nitrogen Fixing Symbiosis
  • Climate Change and Health Impacts
  • Yeasts and Rust Fungi Studies
  • Banana Cultivation and Research
  • Gene expression and cancer classification
  • Antioxidant Activity and Oxidative Stress
  • Nematode management and characterization studies

Agenzia Regionale Prevenzione e Ambiente della Regione Emilia-Romagna
2013-2024

The Ohio State University
2015-2024

College of Wooster
2022-2024

University of Bologna
2007-2021

Public Health England
2021

University of Arizona
2017

Regione Emilia-Romagna
2013-2014

University of Modena and Reggio Emilia
2009-2010

University of Guelph
2001

Abstract Although root architecture has been shown to play an important role in crop performance, particularly under drought conditions, no information is available on the genetic control of traits durum wheat, a largely grown rainfed areas with low rainfall. In our study, panel 57 elite wheat accessions were evaluated controlled conditions for and shoot at seedling stage. Significant variability was detected all that investigated. Correlation analysis suggested features only partially by...

10.1111/j.1744-7348.2007.00198.x article EN Annals of Applied Biology 2007-11-14

Since 1999, a disease of apple caused by an Alternaria sp. has been affecting orchards in northern Italy resulting necrotic spots on leaves and fruit. Forty-four single-spored isolates were obtained from diseased plant materials to investigate the diversity this fungus compare these associated with previous studies, including A. mali, causal agent blotch. All isolates, reference strains, tested for pathogenicity utilizing vitro bioassays detached leaf or fruit (‘Golden Delicious’). In...

10.1094/phyto-04-12-0076-r article EN other-oa Phytopathology 2012-08-30

The neuron-specific K-Cl cotransporter KCC2 maintains low intracellular chloride levels, which are crucial for fast GABAergic and glycinergic neurotransmission. also plays a pivotal role in the development of excitatory glutamatergic neurotransmission by promoting dendritic spine maturation. cytoplasmic C-terminal domain (KCC2-CTD) critical regulatory molecular mechanisms controlling activity through dimerization, phosphorylation, protein interaction. To identify novel CTD motifs, we used Mu...

10.3389/fnmol.2024.1505722 article EN cc-by Frontiers in Molecular Neuroscience 2025-01-15

Emerging and re-emerging plant diseases continue to present multifarious threats global food security. Considerable recent efforts are therefore being channeled towards understanding the nature of pathogen emergence, their spread evolution. Xanthomonas euvesicatoria pv. perforans (Xep ) , one causal agents bacterial spot tomato, rapidly emerged displaced other xanthomonads in many tomato production regions around world. In less than three decades, it has become a dominant xanthomonad systems...

10.1371/journal.ppat.1013036 article EN cc-by PLoS Pathogens 2025-04-09

The determination of genetic relatedness among elite materials crop species allows for more efficient management breeding programs and the protection breeders’ rights. Seventy simple sequence repeats (SSRs) 234 amplified fragment length polymorphisms (AFLPs) were used to profile a collection 58 durum wheat ( Triticum Desf.) accessions, representing most important extant programs. In addition, 42 phenotypic traits, including morphological characteristics recommended official distinctness,...

10.1139/g06-151 article EN Genome 2007-04-01

The development of alternative methods to animal testing is a priority in the context regulatory toxicology. Carcinogenesis field where demand for particularly high. standard rodent carcinogenicity bioassay requires large use animals, high costs, prolonged duration and shows several limitations, which can affect comprehension human relevance carcinogenesis. cell transformation assay (CTA) has long been debated as possible vitro test study This provides an easily detectable endpoint...

10.1093/carcin/bgy037 article EN cc-by-nc Carcinogenesis 2018-03-15

Abstract A large number of basic researches and observational studies suggested the cancer preventive activity vitamin E, but large-scale human intervention trials have yielded disappointing results actually showed a higher incidence prostate although mechanisms underlying increased risk remain largely unknown. Here we show through in vitro vivo that E produces marked inductive effect on carcinogen-bioactivating enzymes pro-oxidant status promoting both DNA damage cell transformation...

10.1038/s41598-019-48213-1 article EN cc-by Scientific Reports 2019-08-12

Perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) are the major components of long-chain per- polyfluorinated alkyl substances (PFAS), known for their chemical stability environmental persistence. Even if PFOA PFOS have been phased out or limited in use, they still represent a concern human health. Several studies per­formed to highlight toxicological behavior these chemicals mode action (MoA). Data suggested causal association between exposure carcinogenicity humans, but...

10.14573/altex.2310281 article EN cc-by ALTEX 2024-01-01

As the novel coronavirus disease sweeps across world several speculations have been made on role that atmospheric factors may played different distribution of SARS-CoV-2 and epidemiological characteristics COVID-19. Knowing environmental play in influenza virus outbreaks, pollution and, particular, airborne (PM) has considered as a potential key factor spread mortality A possible PM carrier also debated. The exacerbating respiratory cardiovascular well recognized. Accumulating evidence...

10.3389/fgene.2020.579964 article EN cc-by Frontiers in Genetics 2020-11-09

The fungal genus Alternaria comprises a large number of asexual taxa with diverse ecological, morphological and biological modes ranging from saprophytes to plant pathogens. Understanding the speciation processes affecting fungi is important for estimating diversity, which in turn affects disease management quarantine enforcement. This study included 106 isolates representing five phylogenetically defined clades two sister sub‐generic groups: section Porri ( A. dauci , solani limicola )...

10.1111/ppa.12749 article EN publisher-specific-oa Plant Pathology 2017-06-26

Bacterial spot (BST) is a highly impactful disease of open-field tomatoes produced in the U.S. Midwest. We combined BST survey data from 2010 to 2013 and 2017 2020 midwestern states characterize BST-causing Xanthomonas species associated with processing tomatoes. identified 1009 spp. strains characterized their temporal/geographical distribution, bactericide resistance, bacteriocin production. This work highlights notable shift study region X. hortorum pv. gardneri perforans over course...

10.1080/07060661.2022.2047788 article EN cc-by-nc-nd Canadian Journal of Plant Pathology 2022-03-08

Bacterial spot (BS) of tomato, caused by Xanthomonas gardneri, X. perforans, vesicatoria, and euvesicatoria, is difficult to control because the high prevalence copper- streptomycin-resistant strains lack resistance cultivars effective bactericides. The objective this study was identify novel growth inhibitors BS-causing (BS-X) species using small molecules (SM; n = 4,182). Several SMs (X1, X2, X5, X9, X12, X16) completely inhibited BS-X isolates (n 68 55 4 32 euvesicatoria) at ≥12.5 µM...

10.1094/phyto-08-20-0341-r article EN other-oa Phytopathology 2021-06-01

Abstract Emerging and re-emerging plant diseases continue to present multifarious threats global food security. Considerable recent efforts are therefore being channeled towards understanding the nature of pathogen emergence, their spread evolution. Xanthomonas euvesicatoria pv. perforans (Xep ), one causal agents bacterial spot tomato, rapidly emerged displaced other xanthomonads in tomato production regions around world. In less than three decades, it has become a dominant xanthomonad...

10.1101/2024.03.22.585974 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2024-03-22

Changes in Xanthomonas race and species composition causing bacterial spot of tomato have occurred throughout the world are often associated with epidemics. Knowledge population structure is key for resistance discovery deployment. We surveyed spp. from processing fields Midwestern United States over a 4-year period between 2017 2020, compared these to strains collected previously, found that X. perforans currently most prevalent species. characterized 564 isolates sequence variation avrXv3...

10.3389/fmicb.2022.826386 article EN cc-by Frontiers in Microbiology 2022-03-18

The Transformics Assay is an in vitro test which combines the BALB/c 3T3 Cell Transformation (CTA) with microarray transcriptomics. It has been shown to improve upon mechanistic understanding of CTA, helping identify mechanisms action leading chemical-induced transformation thanks RNA extractions specific time points along process transformation. In this study, lowest transforming concentration carcinogenic benzo(a)pyrene (B(a)P) tested order find molecular signatures initial events relevant...

10.3390/ijms23147603 article EN International Journal of Molecular Sciences 2022-07-09

Alternative methods to animal testing are considered as promising tools support the prediction of toxicological risks from environmental exposure. Among alternative methods, cell transformation assay (CTA) appears be one most appropriate approaches predict carcinogenic properties single chemicals, complex mixtures and pollutants. The BALB/c 3T3 CTA shows a good degree concordance with in vivo rodent carcinogenesis tests. Whole-genome transcriptomic profiling is performed identify genes that...

10.3390/su6085265 article EN Sustainability 2014-08-13

Anaerobic soil disinfestation (ASD) is a viable option for disease management in tomato production and reduces damage due to soilborne complex consisting of Pyrenochaeta lycopersici, Colletotrichum coccodes, Verticillium dahliae , Meloidogyne spp. There are plentiful options ASD carbon sources using byproducts Midwestern United States agriculture or cover crops, yet these have not been evaluated use settings. Low (10.1 Mg/ha) high (20.2 rates corn gluten meal, distillers dried grains,...

10.3389/fsufs.2021.645197 article EN cc-by Frontiers in Sustainable Food Systems 2021-05-13

The characteristics of 41 native Trichoderma isolates collected from diverse microclimatic domains in Nepal and two Ohio their efficacy biocontrol plant diseases were assessed. Species assignment was based on a maximum likelihood phylogenetic analysis constructed concatenated dataset using the internal transcribed spacer region ( ITS), translocation elongation factor tef1), RNA polymerase II subunit rpb2). Most n = 37) assigned to Viride clade identified as T. asperellum or asperelloides,...

10.1094/phytofr-08-21-0051-r article EN cc-by-nc-nd PhytoFrontiers™ 2022-03-08

Abstract Does religion continue to spur violence even in contemporary times? This work aims shed some light on the relationship between belonging a given and violent behavior. Whereas religions often preach love caring for others (meaning that among believers, decrease level of may be registered), at same time, it could argued religious sense shapes self-identity challenging situations this increases violence, especially towards foreigners. To test hypothesis, we gathered data about yellow...

10.1007/s41996-023-00115-1 article EN cc-by Journal of Economics Race and Policy 2023-04-10
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