A5008756910- Ferroptosis and cancer prognosis
- Cancer-related molecular mechanisms research
- Epigenetics and DNA Methylation
- Inflammatory Biomarkers in Disease Prognosis
- Echinoderm biology and ecology
Zhongkai University of Agriculture and Engineering
2022
Key Laboratory of Guangdong Province
2022
Shandong University
2008
Ferroptosis is a newly discovered form of cell death due to iron-dependent lipid peroxidation. In animal breeding, many environmental factors could lead oxidative stress, which in turn reduce immunity and production performance. Polysaccharide Atractylodes macrocephala Koidz (PAMK) has antioxidation, immunomodulatory, inflammatory modulating effects. For investigating the effect PAMK on splenic ferroptosis gosling caused by lipopolysaccharide (LPS), 40 one-day-old Magang goslings were...
The present study aimed to explore the mechanism by which PAMK alleviates cyclophosphamide (CTX)-induced ferroptosis in thymocytes. One-day-old goslings were divided into four groups (10 goslings/group). CON and CTX fed a basic diet. + diet mixed with (400 mg/kg). Moreover, given daily injection of 40 mg/kg BW (at 19, 20, 21 days age). On other hand, 0.5 mL sterilized saline leg muscle for 28 days. pathway was enriched transcriptome sequencing. Compared group, thymus group underwent injury,...