Vector-borne pathogens (VBPs) are a group of globally extended and quickly spreading that transmitted by various arthropod vectors. The aim the present study was to investigate seroprevalence against Babesia canis, Anaplasma phagocytophilum, Borrelia burgdorferi sensu lato, Leishmania infantum, Dirofilaria immitis, Ehrlichia canis in dogs Croatia. We investigated 435 randomly selected apparently healthy 13 different locations Croatia for antibodies B. indirect immunofluorescence using...

Long-term aerobic exercise during endurance racing places high demands on equine homeostasis. This study aimed to use proteomic analysis elucidate complex biological responses exercise. It was hypothesized that different serum proteome changes would be noted, reflecting physiological processes as a response race. The has been taken before and after an 80 km race from 13 horses. Proteomic of samples performed by TMT-based quantitative method. Apolipoprotein haptoglobin values have validated...

Canine babesiosis is caused by species of the Babesia genus and has become an emerging disease worldwide. To authors' knowledge there are no reports in which antioxidants have been analyzed different presentations canine or prognostic value studied. The aim this study was to evaluate whether oxidative stress could be related severity outcome babesiosis. For purpose a profile consisting four antioxidant biomarkers (superoxide dismutase - SOD, glutathione peroxidase GPx, catalase, total status...

Oxidative stress (OS) associated with an intense exercise may have a negative influence on equine health. The aim of this study was to determine the effects endurance races oxidative and antioxidative status horses by evaluating changes in reactive oxygen metabolites (d-ROMs), malondialdehyde (MDA), biological antioxidant potential (BAP) index (OSI) values. carried out 53 race starts (28 individual horses) competing at different according distance (40 80 km) difficulty (easy demanding)....

Canine babesiosis is a tick-borne disease caused by hemoprotozoan parasites of the genus Babesia. The can be clinically classified into uncomplicated and complicated forms. aim this study was to assess level endothelial activation alterations in fibrinolytic pathway during canine babesiosis. Blood samples were collected on day admission 6th after treatment with imidocarb propionate, from 30 dogs various breeds both sexes naturally occurring B. canis. In prospective study, plasminogen...

Phosphorylation is the most commonly studied protein post-translational modification (PTM) in biological systems due to its importance controlling cell division, survival, growth, etc. Despite thorough research phosphoproteomics of cells and tissues there little information on circulating phosphoproteins. We compared serum from 10 healthy dogs affected by B. canis-caused babesiosis with no organ dysfunctions employing gel-free LC-MS/MS analysis individual samples tandem mass tag (TMT)...

This study aimed to evaluate if exercise-induced acute phase response (APR) occurs in endurance horses the race. The included 23 competing an competition with a successfully passed clinical examination before Blood samples were collected start and within 30 min after end of Haematological biochemical tests performed correlated biomarkers changes. Values calprotectin haptoglobin (Hp) decreased races compared values before, while concentrations ceruloplasmin albumin recorded significant...

Babesiosis is a disease of significant medically and veterinary importance with worldwide distribution. It caused by intra-erythrocyte protozoal parasites, Babesia rossi causing the most severe clinical signs all large parasites infecting dogs. The can be clinically classified into uncomplicated complicated forms wide range presentations from mild, subclinical illness to death. aim this study was assess serum proteomic profiles dogs babesiosis healthy using label-based proteomics approach....

Abstract Elbow joint luxation without concomitant fracture is uncommon in horses. This paper reports on a case of elbow ten months old Arabian colt. The horse was presented with history an acute onset non-weight bearing right front limb lameness edema the affected region lasting for six days. Radiographic imaging indicated joint; however, useful information about severity soft tissue involvement obtained using ultrasonography since bilateral collateral ligaments were completely disrupted....

Probiotics are common adjunctive therapy used in human and veterinary medicine, mostly intended for gastrointestinal diseases treatment or prevention. Lactic acid bacteria: Lactobacilli, bifid bacteria enterococci Saccharomyces boulardii, a subtype of the nonpathogenic yeast have been most frequently as probiotic active ingredients. To become recognized effective probiotic, certain microorganism must fulfill many expectations, primarily ability to survive tract passage, adhere epithelial...

Abstract During intensive physical activity horses are exposed to thermolysis, electrolyte loss and rising amounts of catabolic products, which results in alterations biochemical blood parameters due the horse’s adaptation metabolic stress. The aim present study was determine effect on serum competing 40 80 km endurance races. Blood samples were taken from 28 before after race over four competitions, with a total 53 analyzed. Biochemical studied included creatine kinase, lactate...

Acid-base disturbances have been reported in severe canine babesiosis caused by Babesia rossi (B. rossi), but they not studied B. canis. The objective of this study was to determine the acid-base status, blood gases and electrolyte concentrations naturally occurring canis, compare results those healthy dogs. Two groups animals were used: group 1 consisted 10 dogs, 2 14 dogs infected with following occurred babesiosis: half had a mixed disorder, other simple disorder. most common disorder...

Hypothyroidism is the most commonly diagnosed endocrine disorder in dogs. It produces a deficiency of thyroid hormones which impacts negatively dog's quality life. The objective this study to evaluate possible changes salivary metabolic profile dogs with hypothyroidism. For purpose, targeted metabolomics analysis performed by LC/MS was made saliva samples from group hypothyroidism and healthy Twenty-three metabolites showed significant decrease between hypothyroid dogs, these associated...

Abstract Background The apicomplexan haemoparasite Theileria equi , a causative agent of equine piroplasmosis, is an established pathogen significant welfare and economic concern within the Croatian population. A previous large surveillance study T. has identified two distinct parasite populations, one in north south, geographically separated by Dinaric Alps, which traverse country. This aimed to further investigate genetic diversity these focussing on allelic variability merozoite antigen...

In human and veterinary medicine calprotectin is most widely used in diagnosing different gastro-intestinal diseases. The aim of this study was to assess the stability canine (cCP) serum after storage at low temperatures imprecision method.Blood samples were collected from dogs with clinical diagnoses. Twenty-two included study. Calprotectin concentration measured 4 hours separation (T0), being frozen - 80 °C for 8 (T1) 16 weeks (T2). maximum permissible difference (MPD) derived equation...

Colic in horses is an emergency frequently encountered by clinicians. Prompt and precise evaluation of each case mandatory to determine the need for surgery. Prognosis also a crucial part decision-making process regarding management options. The present study evaluates relevance routinely used haematology biochemistry blood parameters at time patient admission as tools aetiology type prognosis colic cases. Clinical exams analysis were drawn from 46 admitted with signs acute abdominal pain....

Canine babesiosis is world-wide tick-borne disease characterized by erythrocyte destruction, haemolysis and inflammatory response, with increased serum concentrations of positive acute phase proteins a decrease in negative proteins.Some the function as carriers thyroid hormones, so goal this study was to determine non-thyroidal illness syndrome dogs babesiosis.The included 60 26 healthy dogs.Serum thyroxine, thyrotropin transthyretin were determined using ELISA methods, while albumin...

Abstract Babesiosis is a disease of significant veterinary importance with worldwide distribution. It caused by intra-erythrocyte protozoal parasites, Babesia rossi causing the most severe clinical signs all large parasites infecting dogs. The can be clinically classified into uncomplicated and complicated forms wide range presentations from mild, subclinical illness to death. aim this study was assess serum proteomic profiles dogs babesiosis healthy using label-based proteomics approach....

Introduction/Aim: Health literacy is a concept that has been gaining increasing importance in the field of public health and healthcare, even though it use since 1970s. The aim this work to assess level population adult patients who receive their care Pirot Center, as well identify factors may be associated with literacy. Methods: research was conducted form cross-sectional study Center period from 1.5.2024. until 1.6. 2024. 400 respondents participated research. general questionnaire...