A5102733847- Asymmetric Hydrogenation and Catalysis
- Chemical Synthesis and Reactions
- Chemical Synthesis and Analysis
- Catalysis for Biomass Conversion
- Catalytic C–H Functionalization Methods
- Sulfur-Based Synthesis Techniques
- Synthesis and Biological Evaluation
- Ferrocene Chemistry and Applications
- Organoboron and organosilicon chemistry
- N-Heterocyclic Carbenes in Organic and Inorganic Chemistry
- Inorganic and Organometallic Chemistry
- Asymmetric Synthesis and Catalysis
- Fluorine in Organic Chemistry
- Advanced Synthetic Organic Chemistry
- Catalytic Cross-Coupling Reactions
- Polyoxometalates: Synthesis and Applications
- Organic Chemistry Cycloaddition Reactions
- Surface Chemistry and Catalysis
- Porphyrin and Phthalocyanine Chemistry
- Nanomaterials for catalytic reactions
- Oxidative Organic Chemistry Reactions
Zhejiang University of Technology
2005-2022
State Council of the People's Republic of China
2021
Hangzhou Xixi hospital
2021
Yunnan University
2009
Abstract An atom and step economy cascade trifluoromethylation/cyclization of unactivated alkene with Langlois reagent as a CF 3 source is described. A variety polycyclic quinazolinones were successfully synthesized in 52–81% yields under transition metal‐ oxidant‐free conditions. The used this strategy possesses the advantages bench‐stablity, cost‐effectivity high‐efficiency. Additionally, gram‐scale reaction, broad substrate scope good functional group tolerance demonstrated synthetic...
An enantioselective synthesis of 1,4-dihydropyrazolo[4′,3′:5,6]pyrano[2,3-<italic>b</italic>]quinolines from modified MBH carbonates and pyrazolones <italic>via</italic> a chiral phosphine-mediated alkylation/annulation sequence has been realized.
A highly efficient Rh-catalyzed hydrogenation of functionalized olefins has been realized by a new family rigid chiral ferrocenylphosphine-spiro phosphonamidite ligands. Excellent enantiocontrol (>99% ee in most cases) was achieved with wide range α-dehydroamino acid esters and α-enamides. This practicable catalytic system further applied the scalable synthesis optically pure key intermediates cinacalcet d-phenylalanine.
Abstract The iridium/ f ‐diaphos L2 or L9 catalyzed asymmetric hydrogenation of β ‐aryl ‐keto amides (esters), and ‐amino ketones to afford two enantiomers the desired chiral alcohols was realized with 90%‐99% yield 73%‐99% ee . This protocol could be easily conducted on gram scale in presence low catalyst loading (up 9900 TON). Moreover, hydrogenated products are versatile building blocks for a variety biologically active molecules drugs, such as Fluoxetine, Dapoxetine so on. magnified image
Some novel beta-biarylacryl ferrocene derivatives were synthesized via Pd-catalytic Suzuki cross-coupling reactions of beta-(2-bromophenyl)acrylferrocene and arylboronic acids. The structures determined with elemental analyses, IR spectra, (1)H-NMR spectra.
Correction for ‘Enantioselective synthesis of functionalized 1,4-dihydropyrazolo-[4′,3′:5,6]pyrano[2,3-<italic>b</italic>]quinolines through ferrocenyl-phosphine-catalyzed annulation modified MBH carbonates and pyrazolones’ by Xiao <italic>et al.</italic>, <italic>Chem. Commun.</italic>, 2021, DOI: 10.1039/d1cc00989c.