Abstract In recent studies with silver nanoparticles, it has been reported that the use of nanoparticles in carrier drug systems increases tumor suppression and reduces drug-related side effects. At same time, combination traditional medicine nanotechnology provides opportunity to develop new antimicrobial agents. The aim this study was determine anticancer, activities pro-apoptotic effects (AgNPs), carboplatin-loaded (AgNPs-Car). Characterization synthesized were carried out by DLS,...

Carrier system therapies based on combining cancer drugs with nanoparticles have been reported to control tumor growth and significantly reduce the side effects of drugs. We thought that paclitaxel-loaded silver (AgNPs-PTX) were right carrier target cells. also carried out antimicrobial activity experiments as systems formed shown activity. In our study, we used easy-to-synthesize low-cost (AgNPs) biocatalytic photocatalytic advantages drug carriers. investigated antiproliferative activities...

Studies aimed at increasing the efficacy of chemotherapeutic drugs and reducing or completely eliminating their side effects are frequently encountered. In our study, we considered methotrexate (MTX), which is in category anticarcinogenic anti-inflammatory drugs, gemcitabine (GEM), used treatment breast, testicular, ovarian, etc. cancers. GEM, cancers, was covalently bonded to maleic anhydride vinyl acetate (MAVA) copolymer, new polymer–drug conjugates (MAVA–MTX MAVA–GEM) were obtained...

Amaç: Bu çalışmada amaç, farklı yüzey işlemleri uygulanan ve içeceklerde bekletilen protez kaide materyallerinin(DBM) pürüzlülüklerinin mikrobiyal adhezyonunun karşılaştırmaktadır. Materyal Metod: Farklı DBM'lerden 240 disk şekilli numune hazırlandı; otopolimerize akrilik reçine, ısıyla polimerize edilmiş reçine üretan dimetakrilat reçine. Numuneler işleme yöntemlerine göre iki ana gruba ayrıldı; geleneksel polisaj (Cp) optiglaze (Og) kaplama ajanı. Bekletilen içeceğe (distile su, siyah çay,...

In endodontics, the elimination of resistant bacteria such as Enterococcus faecalis plays an important role for treatment success in root canals. Therefore, new alternative irrigants (instead sodium hypochlorite) have been researched to achieve ideal endodontic treatment.The aim present study was evaluate and compare antibacterial effect aqueous ozone with different concentrations techniques application (manual ultrasonic) against E. human canals.Eighty single-root mandibular premolar teeth...

In this study; It was aimed to investigate the cytotoxic activities and antimicrobial effects of Palmarosa essential oil obtained from Cymbopogon martinii plant. Content analyzes were made by Gas Chromatopraphy-Mess Spectrometry (GS-MS). The investigated using Disk Diffusion Minimum Inhibition Concentration (MIC) methods. Cytotoxic at different concentrations in breast cancer (MCF-7), prostate (DU-145) healthy human fibroblast (WI-38) cell lines XTT (2,3-bis-(2-methoxy-4-nitro-5)...

The success of endodontic treatment depends on a few crucial factors. One these factors is the complete chemomechanic preparation root canal against various bacteria. In particular, effect resistant bacteria may cause intense pain with flare-up and formation periapical lesions. Therefore, strong irrigants plays an important role in terms elimination to achieve long-term successful treatment.The aim this study was investigate antibacterial effects super-oxidized water (SPO) canals infected...

The purpose of this study was to investigate the antibacterial effects two different types laser and aqueous ozone in human root canals infected by Enterococcus faecalis.Many techniques have been developed find an alternative sodium hypochlorite as a disinfection agent for canals. However, no has evaluated exactly same antimicrobial with (NaOCl).Eighty mandibular premolar teeth single roots were selected. Following canal preparation irrigation, sterilization performed autoclave. E. faecalis...

Objective: To investigate the antioxidant, antimicrobial, and anticancer effects of Achillea filipendulina . Methods: Phytochemical content was analyzed by GC-MS. Antioxidant activity assayed DPPH, total antioxidant status, oxidant iron reduction tests. Antimicrobial assessed using MIC assay. Anticancer detected via MTT assay, followed analysis apoptotic process annexin V caspase 3/7. miR-519d Dvl-1 expression were RT-PCR, molecular docking also performed. Results: The ethanol extract showed...

To evaluate the bacterial extrusion during instrumentation with different nickel titanium (NiTi) engine-driven instruments.Ninety extracted single-canal human mandibular incisor teeth were inoculated Enterococcus faecalis to obtain biofilm formation and randomly divided 6 groups (n=15). One group served as control was not instrumented; other prepared ProTaper Gold (PTG; Dentsply Maillefer, Ballaigues, Switzerland), WaveOne (WOG; Maillefer), Twisted File Adaptive (TFA; SybronEndo, Orange, CA,...

Purpose: The aim of the present study was to evaluate and compare antibacterial effects various irrigation solutions against Staphylococcus aureus (S. aureus) in human root canals. Materials Methods: 120 single-root mandibular premolar teeth were selected. prepared sterilized. S. incubated canals kept at 37°C for 24h. infected divided into one positive (saline) negative (sodium hypochlorite) control, four experimental groups [Ethylene-diaminetetra-aceticacid, Chlorhexidine Gluconate,...

Antibiotic-loaded acrylic bone cement (polymethylmethacrylate, PMMA) is used to prevent or treat infection in total joint replacement surgery. The purpose of this study was investigate biocompatibility and cytotoxicity the teicoplanin-loaded cement. Cytotoxicity examination balls 400 mg teicoplanin added conducted by MTT (3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyl tetrazolium bromide) assay. SEM (Scanning electron microscopy) observe adhesion spreading cells on surface balls. assay...

The aim of the study was to evaluate antimicrobial activity the-potassium-titanyl-phosphate--the KTP laser and ozone in primary root canals.Sixty incisor teeth were selected. specimens inoculated with 10 mL Enterococcus faecalis (E. faecalis). Groups: (1,5 W); gaseous (150 s); sodium hypochlorite (NaOCl); saline group. Sterile paper points used sample bacteria from canals tubes containing 5 brain heart infusion broth. Then, suspension incubated culture media for 24 h. Data analyzed...

Objective: Biofilm is a structure formed by group of microorganisms. Bacteria in the biofilm lead to much more serious problems medical and industrial terms when compared their planktonic forms. In this sense, it important know about activities The ability certain microorganism strains form biofilms was shown, importance subject tried be emphasized study. Methods: Fifteen bacteria two yeast standard were used Microtiter plate method order determine production capacities strains. formations...

Abstract Objectives In this study, we aimed to detect the chemical compounds of Thymbra capitata ethanolic extract (TC-EtOH) as well evaluated its antimicrobial, antioxidant, cytotoxic activities, and in vivo wound healing effects. Methods The composition TC-EtOH was analyzed by Gas chromatography-mass spectrometry (GC-MS). Antioxidant antimicrobial properties were determined with 2,2-diphenyl-1-picrylhydrazyl (DPPH), disc diffusion test broth micro-dilution (minimal inhibitory concentration...

Background: Candida albicans is one of the important microorganism which can be isolated from normal flora in mouth. The resistance C. against disinfectants like ozone reduce success rate root canal treatments. Objectives: current study aimed to investigate antifungal efficacy aqueous and gaseous human canals infected by albicans. Materials Methods: Fifty single-root mandibular premolar teeth were selected. prepared sterilized. incubated kept at 37°C for 24 h. divided into positive, negative...

In this study; it was aimed to investigate the anticancer and cytotoxic activities on DU-145 prostate cancer MCF-7 breast cell lines WI-38 human fibroblast line of essential oil (Nioli) obtained from Melaleuca viridiflora Sol. ex Gaertn. plant its antimicrobial effects various bacteria yeast cells. Content analyzes Nioli were made by Gas Chromatography-Mass Spectrometry (GK-KS). The determined using Disk Diffusion Minimum Inhibition Concentration (MIC) tests. Its XTT (2,3-bis-(2-methoxy-4-)...

In recent years, the use of medicinal plants as sources drugs or herbal extracts has been great importance. Passiflora edulis is nowadays widely studied for its antimicrobial, anticancer, and antioxidant potential. Therefore, this study aimed to determine phytochemical structure ethanol extract P. leaves investigate biological properties such antimicrobial anticancer activities. The was obtained analyzed by GC-MS. activity leaf determined MIC test. XTT method used antiproliferative activity....

Objective: This study aimed to compare the cytotoxicity and antimicrobial activity of a light-cured adhesive system self-cured from same company. Materials Methods: A Tokuyama BOND force II (Light-cured) (TF2B) Universal Bond (Self-cured) (TUB) were selected for study. The evaluation these two systems on cell cultures was performed using MTT assay Agar Diffusion in L929 fibroblast cells. Disk diffusion method liquid microdilution (MIC) used evaluate their activity. experiments 6 pathogenic...

Abstract Capsicum annuum L. species from the Samandağ district of Hatay/Turkey was used in our study. Phytochemical analysis seed and fruit ethanol extracts this plant carried out by GC‐MS method. Total Antioxidant Status (TAS) Oxidant (TOS) levels were determined to calculate Oxidative Stress Index determine antioxidant activity. MIC method evaluate antimicrobial properties against pathogenic bacteria fungi. Anticancer activity XTT assay on breast (MCF‐7), lung (A549) brain (C6) cancer...

The present study evaluated the antibacterial effects of aqueous and gaseous ozone in human root canals infected with Enterococcus faecalis. Infected were divided into two control groups (saline, sodium hypochlorite) three experimental (manual or ultrasonic technique and, ozone). Disinfection procedures performed, remaining microbial colonies counted data evaluated. Sodium hypochlorite showed highest effect on Enteroccous Moreover, appear to be more influential than manual ozone.