- Obsessive-Compulsive Spectrum Disorders
- Employment and Welfare Studies
- Epilepsy research and treatment
- COVID-19 and Mental Health
- Healthcare professionals’ stress and burnout
- Autism Spectrum Disorder Research
- Neurological disorders and treatments
- Mental Health and Psychiatry
- Psychosomatic Disorders and Their Treatments
- Workplace Health and Well-being
- Health disparities and outcomes
- Pharmacological Effects and Toxicity Studies
- Parkinson's Disease Mechanisms and Treatments
- Grief, Bereavement, and Mental Health
- School Choice and Performance
- Functional Brain Connectivity Studies
- Global Health Care Issues
- Migration, Health and Trauma
- Health, psychology, and well-being
- Geriatric Care and Nursing Homes
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Maternal Mental Health During Pregnancy and Postpartum
- Schizophrenia research and treatment
- COVID-19 and healthcare impacts
- Body Image and Dysmorphia Studies
University of California, Los Angeles
2024
Queen's University Belfast
2012-2023
King's College London
2010-2020
Queens University
2020
Royal Victoria Hospital
2016
University of Ulster
2016
Olive View-UCLA Medical Center
2016
South London and Maudsley NHS Foundation Trust
2005-2015
Institute of Public Health
2015
King's College Hospital
2005-2013
The mind's ability to think about the mind has attracted substantial research interest in cognitive science recent decades, as 'theory of mind'. No attempted identify brain basis this ability, probably because it involves several separate processes. As a first step, we investigated one component process-the recognise mental state terms.In Experiment 1, tested group children with autism (known have theory deficits) and control handicap, for their terms word list. This was test if recognition...
In this report, we detail the results of 2010 BTS national pleural procedures audit, to which 58 hospitals covering a collective population more than 20 million patients contributed data regarding local procedure practice and training policies process complications associated with total 824 chest drain insertions. The highlight promising increase in use real time ultrasound guidance for but also deficiencies pre-procedure consent significant rate avoidable minor such as fall-out related...
The coronavirus disease 2019 (COVID-19) was declared a global pandemic in early 2020. Due to the rapid spread of virus and limited availability effective treatments, health social care systems worldwide quickly became overwhelmed. Such stressful circumstances are likely have negative impacts on workers’ wellbeing. current study examined relationship between coping strategies wellbeing quality working life nurses, midwives, allied professionals, workers who worked UK during its first wave...
<h3>OBJECTIVES</h3> To examine prospectively the frequency and nature of psychiatric symptoms seen in patients during first three months after temporal lobe surgery for chronic intractable epilepsy addition to study relation between presurgical mental state, laterality surgery, postsurgical seizure course. <h3>METHOD</h3> A consecutive series 60 being assessed were studied. They interviewed before at six weeks again operation. <h3>RESULTS</h3> At half those with no psychopathology...
Abstract Social workers play a vital role in maintaining and improving the lives of service users that they work with. Despite this, is replete with high levels stress-related sickness absence, turnover intentions low jobs satisfaction addition to poor working conditions. This study sought further investigate conditions UK social workers, as well reasons for these via mixed-methods survey interview study. A total 3,421 responses were gained from cross-sectional which looked at conditions,...
<h3>Background</h3> Gold standard protocols have yet to be established for the treatment of motor conversion disorder (MCD). There is limited evidence support inpatient, multidisciplinary intervention in chronic, severe cases. <h3>Aims</h3> To evaluate characteristics and outcomes MCD patients admitted a specialist neuropsychiatric inpatient unit. <h3>Methods</h3> All Lishman Unit (years 2007–2011) with diagnosis were included. Data relevant status regard mobility, activities daily living...
Nurse, Midwives and Allied Health Professionals (AHPs), along with other health social care colleagues are the backbone of healthcare services. They have played a key role in responding to increased demands on during COVID-19 pandemic. This paper compares cross-sectional data quality working life, wellbeing, coping burnout nurses, midwives AHPs United Kingdom (UK) at two time points An anonymous online repeated survey was conducted timepoints, Phase 1 (7th May 2020-3rd July 2020); 2 (17th...
The neuroanatomic or neuropathologic basis of Gilles de la Tourette9s syndrome (GTS) remains unknown. Recent studies have suggested abnormalities cerebral asymmetry and basal ganglia volumes. We studied 17 patients with GTS eight normal controls using volumetric MRI techniques for measuring the caudate nucleus, amygdala, corpus callosum. One subject was subsequently excluded because he left handed. No absolute differences in nucleus volumes between patient control groups were evident. There...
Background Functional brain imaging with technetium-99m d,l-hexamethyl propyleneamine oxime (HMPAO) Single Photon Emission Tomography (SPET) allows us to explore the cerebral pathophysiology of Gilles de la Tourette's Syndrome (GTS). Method Fifty patients and 20 controls were examined. Patients rated for tic severity mood. Scans analysed quantitatively using internal ratios occipital cortex. Results differed from on measures relative blood flow left caudate, anterior cingulate cortex...
This paper reports and discusses the weekly Clapping for Carers – described as 'front-line heroes' that took place across United Kingdom during first national lockdown of coronavirus pandemic. Data are drawn from a UK-wide online survey health social care workers, completed in May to July 2020. The received 3,425 responses which 2,541 were analysed; free-text comments categorised. One question asked specifically: 'Do you think "Clap Carers" was helpful response public?', 815 provided....
Many health and social care (HSC) professionals have faced overwhelming pressures throughout the COVID-19 pandemic. As current situation is constantly changing, some restrictions across UK countries such as distancing mask wearing in this period (May–July 2021) began to ease, it important examine how workforce has been affected employers can help rebuild their services. The aim of study was compare cross-sectional data collected from HSC at three time points during pandemic: Phase 1 2020), 2...
Thirty‐seven pupils attending a special school for children and adolescents with autism were observed the presence of motor vocal tics. Subsequent family interviews confirmed diagnosis comorbid Gilles de la Touretteapos;s Syndrome (GTS) in three autism, giving minimum prevalence rate 8.1%. Family history data also suggested this was heritable. The GTS not associated superior intellectual, language, or social development. Results suggest that may exceed expected by chance. limited sample size...
OBJECTIVES: In a study of patients with focal epilepsy the hypothesis was explored that different measurements psychopathology are related to specific distributions cerebral perfusion. METHODS: Forty had SPECT performed (99m)Tc-HMPAO. addition, received psychiatric evaluation following questionnaires: Beck depression inventory, Leyton obsessionality Bear-Fedio questionnaire, and social stress support interview. Patients were analysed in two groups according laterality epilepsy. Nine excluded...
Autoimmune thyroid disease is associated with enhanced expression of major histocompatibility complex class I antigens on thyrocytes. To better understand this phenomenon, we have studied the normal genes in FRTL-5 rat cells. A variety hormones and growth factors that regulate function these cells were found to decrease RNA levels: serum, insulin or insulin-like factor-I (IGF-I), hydrocortisone. Antibody preparations from Graves' patients (thyroid-stimulating antibodies), which increase cAMP...
Abstract During the COVID-19 pandemic interest into its potential impact on mental well-being has intensified. Within social care sector, increased job demands and prolonged stress taking a disproportionate toll workforce, particularly workers. This article compares quality of working life workers in United Kingdom (UK) before during pandemic. Data were collected 2018 (N = 1,195) 2020 1,024) using two cross-sectional surveys. To account for differences between datasets, propensity score...
the health impacts of caregiving and volunteering are rarely studied concurrently, despite potential for both synergies conflicts. This population-based study examines association these activities on subsequent mortality.a census-based record-linkage 244,429 people aged 65 over, with cohort characteristics, status, presence chronic conditions derived from Census returns. Mortality risk was assessed over following 45 months adjustment baseline characteristics.caregivers volunteers were...
Stress and mental health are among the biggest causes of sickness absence in UK, with Social Work Care sectors having highest levels stress all professions UK. Chronically poor working conditions known to impact employees' psychological physiological health. The spread COVID-19 pandemic has affected both mode method work Work. Through a series cross-sectional online surveys, completed by total 4,950 UK Workers, this study reports changing well-being Workers at two time points (phases) during...
Thyrocytes normally express major histocompatibility complex (MHC) class I, but not II, cell surface antigens. A rat thyrocyte line, FRTL-5, also expresses MHC I antigens, in addition to a variety of thyroid-specific genes. Treatment FRTL-5 thyrocytes with physiological concentrations thyroid-stimulating hormone (TSH) has been shown induce increased expressed thyroglobulin and thyroid peroxidase simultaneously decrease expression the TSH receptor. The reduction receptor by is cAMP mediated....
We compared the mental health risk to unpaid caregivers bereaved of a care recipient with persons otherwise and nonbereaved caregivers.We linked prescription records for antidepressant anxiolytic drugs characteristics life-event data members Northern Ireland Longitudinal Study (n = 317 264). Using case-control design, we fitted logistic regression models, stratified by age, model relative likelihood problems, using proxy measures health-related prescription.Both individuals were estimated be...
As the COVID-19 pandemic continues to evolve around world, it is important examine its effect on societies and individuals, including health social care (HSC) professionals. The aim of this study was compare cross-sectional data collected from HSC staff in UK at two time points during pandemic: Phase 1 (May-July 2020) 2 (November 2020-January 2021). surveyed consisted nurses, midwives, allied professionals, workers across (England, Wales, Scotland, Northern Ireland). Multiple regressions...