- Health Systems, Economic Evaluations, Quality of Life
- Pharmaceutical Economics and Policy
- Healthcare cost, quality, practices
- Economic and Environmental Valuation
- Biomedical Ethics and Regulation
- Viral gastroenteritis research and epidemiology
- Healthcare Policy and Management
- Fungal Biology and Applications
- Clinical practice guidelines implementation
- Hepatitis Viruses Studies and Epidemiology
- Meta-analysis and systematic reviews
- Intellectual Property and Patents
- Global Health Care Issues
- Biotechnology and Related Fields
- Thyroid Cancer Diagnosis and Treatment
- Adolescent and Pediatric Healthcare
- Pharmaceutical industry and healthcare
- Phytochemicals and Antioxidant Activities
- Pharmaceutical studies and practices
- Viral Infections and Immunology Research
- Trace Elements in Health
- Artificial Intelligence in Healthcare and Education
- Chromium effects and bioremediation
- Polyamine Metabolism and Applications
- Lipoproteins and Cardiovascular Health
Institut National d'Excellence en Santé et en Services Sociaux
2020-2022
Université de Montréal
2012-2022
Royal Australasian College of Surgeons
2017
The University of Adelaide
2017
New York University Press
2017
Cambridge University Press
2017
Centro Laser
2015
TransCanada (Canada)
2009-2015
Biocom
2006-2012
MedCom
2006-2012
Resource allocation is a challenging issue faced by health policy decisionmakers requiring careful consideration of many factors. Objectives this study were to identify decision criteria and their frequency reported in the literature on healthcare decisionmaking.An extensive search was performed Medline EMBASE articles reporting criteria. Studies conducted with (e.g., focus groups, surveys, interviews), conceptual review describing multicriteria tools included. Criteria extracted, organized...
Background. Health care decision making is complex and requires efficient explicit processes to ensure transparency consistency of factors considered. Objectives. To pilot an adaptable decision-making framework incorporating multicriteria analysis (MCDA) in health technology assessment (HTA) with a pan-Canadian group policy clinical makers researchers appraising 10 medicines covering 6 therapeutic areas. Methods. An appraisal was convened participants were asked express their individual...
BACKGROUND: Methicillin‐resistant Staphylococcus aureus (MRSA) has become endemic worldwide in hospitals, and community‐associated MRSA is spreading into the community at large. OBJECTIVES: To estimate current cost of Canada to assess magnitude this public health issue. METHODS: An extensive review literature was conducted gather epidemiology, care resource utilization data for Canadian settings. The burden estimated using available most recent epidemiology data. RESULTS: rate hospitals...
Abstract Background Consistent healthcare decisionmaking requires systematic consideration of decision criteria and evidence available to inform them. This can be tackled by combining multicriteria analysis (MCDA) Health Technology Assessment (HTA). The objective this study was field-test a support framework (EVIDEM), explore its utility drug advisory committee test reliability over time. Methods Tramadol for chronic non-cancer pain selected the health plan as case relevant their context....
To test and further develop a healthcare policy clinical decision support framework using growth hormone (GH) for Turner syndrome (TS) as complex case study. The EVIDEM was developed to complement the multicriteria analysis (MCDA) Value Matrix, that includes 15 quantifiable components of clustered in four domains (quality evidence, disease, intervention economics), with qualitative tool including six ethical health system-related decision. An extensive review literature performed technology...
Objectives: The aim of this study was to gather qualitative and quantitative data on criteria considered by healthcare decision makers. Methods: Using snowball sampling an online questionnaire with forty-three organized into ten clusters, makers were invited international task force report which they consider when making decisions interventions in their context. Respondents reported whether each criterion is “currently considered,” “should be its relative weight (scale 0–5). Differences...
The multiplicity of issues, including uncertainty and ethical dilemmas, policies involved in appraising interventions for rare diseases suggests that multicriteria decision analysis (MCDA) based on a holistic definition value is uniquely suited this purpose. objective study was to analyze further develop comprehensive MCDA framework (EVIDEM) address disease issues policies, while maintaining its applicability across areas.Specific were identified through literature review. Ethical...
The aim of this study was to adapt and assess the value a Multi-Criteria Decision Analysis (MCDA) framework (EVIDEM) for evaluation Orphan drugs in Catalonia (Catalan Health Service).The standard decision-making procedures CatSalut were compared with EVIDEM methodology contents. adapted Catalan context, focusing on (PASFTAC program), during Workshop sixteen PASFTAC members. criteria weighting done using two different techniques (nonhierarchical hierarchical). Reliability assessed by...
There is an increased interest in the use of multi-criteria decision analysis (MCDA) to support regulatory and reimbursement making. The EVIDEM framework was developed provide pragmatic health care, estimate value healthcare interventions, aid priority-setting. objectives this study were test 1) influence different weighting techniques on overall outcome MCDA exercise, 2) discriminative power criteria such techniques, 3) whether result similar weights set proposed by framework.A sample 60...
Systematic and transparent approaches to priority setting are needed, particularly in low-resource settings, produce decisions that sound acceptable stakeholders. The EVIDEM framework brings together Health Technology Assessment (HTA) multi-criteria decision analysis (MCDA) by proposing a comprehensive set of criteria with standardized processes support decisionmaking. objective the study was field test for decisionmaking on screening private health plan South Africa.Liquid-based cytology...
The objective of the study was to reveal through pragmatic MCDA (EVIDEM) contribution a broad range criteria value orphan drug lenvatinib for radioiodine refractory differentiated thyroid cancer (RR-DTC) in country-specific contexts. designed enable comprehensive appraisal (12 quantitative, 7 qualitative criteria) current disease context (watchful waiting, sorafenib) France, Italy and Spain. Data on collected from diverse stakeholders during panels included: weights (individual social...
BACKGROUND: Clostridium difficile infection (CDI) represents a public health problem with increasing incidence and severity. OBJECTIVE: To evaluate the clinical economic consequences of vancomycin compared fidaxomicin in treatment CDI from Canadian care system perspective. METHODS: A decision‐tree model was developed to compare for severe CDI. The assumed identical initial cure rates included first recurrent episodes (base case). Treatment patients presenting examined as an alternative...
Health technology assessment and healthcare decision-making are based on multiple criteria evidence, heterogeneous opinions of participating stakeholders. Multi-criteria decision analysis (MCDA) offers a potential framework to systematize this process take different perspectives into account. The objectives study were explore preferences across German stakeholders when appraising interventions, using multi-criteria heart pulmonary sensor as case study. An online survey 100 was conducted...