A5009978711- T-cell and B-cell Immunology
- Thermal Regulation in Medicine
- FOXO transcription factor regulation
- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Immune Cell Function and Interaction
- Infant Nutrition and Health
- Childhood Cancer Survivors' Quality of Life
- Analytical chemistry methods development
- Circadian rhythm and melatonin
- Gut microbiota and health
- Education during COVID-19 pandemic
- Healthcare Regulation
- Adrenal Hormones and Disorders
- Healthcare during COVID-19 Pandemic
- Digestive system and related health
- Heat shock proteins research
- Biosensors and Analytical Detection
- Electrochemical sensors and biosensors
- Immunotherapy and Immune Responses
i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto
2019-2024
Universidade do Porto
2021-2024
Instituto de Biologia Molecular e Celular
2022-2023
Universidade Nova de Lisboa
2023
The design and synthesis of artificial receptors based on molecular imprinting (MI) technology for the development a new MIP-based biosensor detection stress biomarker α-amylase in human saliva point-of-care (PoC) applications is described this work. portable electrochemical devices monitoring consists cost-effective disposable gold screen-printed electrodes (AuSPEs). To build device, template biomolecule was firstly immobilized directly over working area chip previously activated with...
A prática de automedicação consiste na utilização medicamentos sem prescrição ou acompanhamento qualquer profissional saúde para tratar seus sintomas atuais como medida profilática. Este hábito está presente no mundo inteiro, sendo adotada pelas mais variadas idades e áreas atuação, incluindo profissionais saúde. Durante a pandemia COVID-19, apresentou evidência devido euforia em relação ao SARS-CoV-2, feito o usa das medicações pela população mundial. Objetivo: estudo tem objetivo analisar...
Within the thymus, thymic epithelial cells (TECs) provide dedicated stroma microenvironments for T cell development. Because TEC functionality is sensitive to aging and cytoablative therapies, unraveling molecular elements that coordinate their thymopoietic role has fundamental clinical implications. Particularly, selection of CD4 depends on interactions between TCRs expressed precursors self-peptides:MHC II complexes presented by cortical TECs (cTECs). Although...
Within the thymus, thymic epithelial cells (TECs) create dedicated microenvironments for T cell development and selection. Considering that TECs are sensitive to distinct pathophysiological conditions, uncovering molecular elements coordinate their thymopoietic role has important fundamental clinical implications. Particularly, medullary (mTECs) play a crucial in central tolerance. Our previous studies, along with others, suggest mTECs depend on factors linked genome-protecting pathways, but...
Early-life gut dysbiosis has been associated with an increased risk of inflammatory, metabolic, and immune diseases later in life. Data on microbiota changes infants undergoing intestinal surgery requiring enterostomy are scarce. This prospective cohort study examined the effluent 29 who underwent due to congenital malformations gastrointestinal tract, necrotizing enterocolitis, or spontaneous perforation. Initial samples were collected immediately after final three weeks later. Gut...
<title>Abstract</title> Within the thymus, thymic epithelial cells (TECs) create dedicated microenvironments for T-cell development and selection. Considering that TECs are sensitive to distinct pathophysiological conditions, uncovering molecular elements coordinate their thymopoietic role has important fundamental clinical implications. Particularly, medullary (mTECs) play a crucial in central tolerance. Our previous studies, along with others, suggest mTECs depend on factors linked...