- Urinary Bladder and Prostate Research
- Sarcoma Diagnosis and Treatment
- Nutrition and Health in Aging
- Reproductive System and Pregnancy
- Vascular Tumors and Angiosarcomas
- Medical Research and Treatments
- Cardiac electrophysiology and arrhythmias
- Mitochondrial Function and Pathology
- Salmonella and Campylobacter epidemiology
- Infant Health and Development
- Cancer Risks and Factors
- Reproductive Biology and Fertility
- Respiratory and Cough-Related Research
- Electron Spin Resonance Studies
- Biochemical effects in animals
- Metabolism and Genetic Disorders
- Heavy Metal Exposure and Toxicity
- Phytoestrogen effects and research
- Phytochemical compounds biological activities
- Antioxidant Activity and Oxidative Stress
- Hemispheric Asymmetry in Neuroscience
- Acute Myeloid Leukemia Research
- Biomarkers in Disease Mechanisms
- Gastric Cancer Management and Outcomes
- Estrogen and related hormone effects
Soochow University
2022
Xuzhou Central Hospital
2022
Second Affiliated Hospital of Dalian Medical University
2019
Fox Chase Cancer Center
2017
Sun Yat-sen University
2008
Xiyuan Hospital
2005
Capital Medical University
2004
Ningbo Municipal People's Government
2001
Melatonin is a hormone naturally produced by the pineal gland in brain. In addition to modulating circadian rhythms, it has pleiotropic biological effects including antioxidant, immunomodulatory, and anti-cancer effects. Herein, we report that melatonin ability decrease growth metastasis of androgen-dependent prostate cancer.To evaluate effect on androgen-sensitive cancer vitro or vivo, cell proliferation, apoptosis, migration invasion were analyzed using...
Abstract Aims: The objective of this study was to investigate the efficacy and toxic side effects two combinations methotrexate, cisplatin, doxorubicin ifosfamide on treating Chinese osteosarcoma patients. Methods: A retrospective analysis conducted 185 patients treated with four drugs mentioned above. total 93 received Italian therapeutic treatment (IOR‐OS/N‐5: Instituto Ortopedic Rizzoli‐Section Osteosacorma/Neoadjuvant chemotherapy‐5) remaining 92 optimized by our department. We compared...
Bone marrow-derived mesenchymal stem cells (BMSCs) and their exosomes are of great significance for the recovery cardiac function in patients with myocardial infarction (MI). However, underlying mechanisms BMSCs applied to MI treatment remain unclear. Fluorescence-activated cell sorting (FACs) performed assess apoptosis, reactive oxygen species levels glucose uptake capacity BMSCs. Reverse transcription polymerase chain reaction is conducted detect vascular endothelial growth factor (VEGF),...
Abstract Rationale: Primary cranial vault lymphoma (PCVL) is an extremely rare extranodal in the skull. This case study investigates clinical features, so as to improve understanding of diagnosis and therapy. Patient concerns: A 31-year-old male presented painful scalp mass at site 1-month-old head trauma. Diagnosis: The final was plasma cell lymphoma, which a subtype diffuse large B-cell based on biopsy immunohistochemistry findings. Interventions: patient received total tumor resection...
The kallikrein-related (KLKs) peptidases are implicated in prostate and ovarian cancer invasion/metastasis via activation of growth factors, proteases extracellular matrix degradation involved in. In our published work, we used cell biology approaches to show novel associations KLK with processes indicative metastasis the potential sunflower trypsin inhibitor scaffold-engineered KLK4 inhibitor. Our current studies directed towards discovering precise target proteins/substrates subsequent...
Objective: To assess the survival benefit of whole brain radiotherapy (WBRT) for patients with controlled extra-cranial disease and those favorable diagnosis-specific graded prognostic assessment (dsGPA) scores within EORTC 22952. Methods: In 22952 trial, 1–3 metastases stable systemic or asymptomatic primary tumors were randomized to WBRT versus observation prior stereotactic radiosurgery (SRS) after surgical resection. We performed exploratory analyses using cox regression, Kaplan-Meier...
Objective To study the clinical efficacy of permanent implantation radioactive particles I125 combined with external radiation in treatment bone metastatic prostate cancer. Methods A retrospective 37 patients advanced cancer who were treated at Xuzhou Central Hospital from January 2016 to December 2017 was carried out. The divided into two groups according plan: therapy group and endocrine group. baseline data age, sex, Gleason score, PSA, B-ultrasound volume, ECT scan metastases,...