A5043946162- biodegradable polymer synthesis and properties
- Herpesvirus Infections and Treatments
- Dyeing and Modifying Textile Fibers
- Adsorption and biosorption for pollutant removal
- Food composition and properties
- Textile materials and evaluations
- Immune Cell Function and Interaction
- Virus-based gene therapy research
- Electrospun Nanofibers in Biomedical Applications
- Plant Virus Research Studies
- T-cell and B-cell Immunology
- Advanced Polymer Synthesis and Characterization
- RNA modifications and cancer
- Machine Fault Diagnosis Techniques
- Microplastics and Plastic Pollution
- Advanced Cellulose Research Studies
- Extraction and Separation Processes
- Immunotherapy and Immune Responses
- Insect and Pesticide Research
- Potato Plant Research
- Cancer-related Molecular Pathways
- Recycling and Waste Management Techniques
- Photopolymerization techniques and applications
- Optimization and Mathematical Programming
- Mechanical Failure Analysis and Simulation
National Research Centre
2012-2024
Michigan State University
2023-2024
Helwan University
2008-2023
Michigan United
2023
Versiti Blood Center of Wisconsin
2019-2021
Stanford University
2013-2016
Security Forces Hospital
1999-2015
Menoufia University
2013
University at Buffalo, State University of New York
2008-2012
King Khalid University Hospital
1999
ABSTRACT The human papillomavirus (HPV) oncoprotein E7 is a relatively short-lived protein required for HPV-driven cancer development and maintenance. degraded through ubiquitination mediated by cullin 1 (CUL1) the ubiquitin-conjugating enzyme E2 L3 (UBE2L3). However, proteins are maintained at high levels in most HPV-positive cells. A previous proteomics study has shown that UBE2L3 CUL1 increased knockdown of E3 ubiquitin ligase membrane-associated ring-CH-type finger 8 (MARCHF8). We have...
Abstract Maize starch was reacted with monochloroacetic acid in presence of sodium hydroxide. The reaction involved is known as carboxymethylation. latter carried out under a variety conditions. For every set conditions carboxymethylation studied respect to the extent expressed degree substitution (DS) and efficiency (RE). Results indicated that starch:water ratio 1:2.5 constitutes optimal material liquor ratio. Increasing hydroxide concentration up 8N causes significant enhancement DS R. E....
The ability of potassium permanganate in the presence different acids to induce grafting methyl methacrylate and acrylonitrile onto sodium hydroxide-treated cotton, partially carboxymethylated cyanoethylated acetylated cotton was investigated. copolymerization reaction carried out under a variety conditions. graft yields are greatly enhanced by increasing concentration monomer, time, temperature. opposite holds true for initiator at higher concentrations. effectiveness was: nitric acid >...
The membrane-associated RING-CH-type finger ubiquitin ligase MARCHF8 is a human homolog of the viral ligases Kaposi’s sarcoma herpesvirus K3 and K5 that promote host immune evasion. Previous studies have shown ubiquitinates several receptors, such as major histocompatibility complex II CD86. While papillomavirus (HPV) does not encode any ligase, oncoproteins E6 E7 are known to regulate ligases. Here, we report expression upregulated in HPV-positive head neck cancer (HNC) patients but...
Autoimmune diseases, such as multiple sclerosis (MS), are often chronic with no cures. An underlying commonality of autoimmune diseases is immune-mediated inflammation. Control inflammation achieved by steroids and disease-modifying therapies, which can result in severe side-effects. CD4+Foxp3+ T regulatory cells (Treg), essential to controlling responses considered a strong therapeutic target minimal side effects. To that end, we leveraged our identification B cell IgD low (BDL) control...
Three types of starch derivatives containing amide groups were used in removal heavy metal ions from their solutions. These poly(acrylamide)–starch graft copolymer, carbamoylethylated starch, and carbamate. The different factors affecting ion adsorption on these substrates, such as pH, concentration, type derivatives, treatment time, temperature, studied. Results obtained indicate that the copolymer was a selective adsorbant for Hg2+ at pH 0.5–1. values ofdifferent follow order > Cu2+ Zn2+...
Abstract Acetylation of native hydrolyzed and oxidized, maize starch has been studied. The different factors affecting acetylation process were investigated. These include liquor ratio, acetic anhydride, perchloric acid concentration, reaction time temperature. Also investigated characterization application the acetylated starches in textile warp sizing. acetyl content increases to reach a maximum then decreases on increasing either ratio or concentration. it with anhydride concentration...
Abstract Preparation of carboxymethyl starch using chloroacetic acid and sodium hydroxide was investigated under different conditions. The carboxymethylation reaction studied with respect to the degree substitution (D. S.) efficiency (R. E.) variables included concentration reactants liquor ratio as well time temperature. D. S. R. E. were greatly enhanced by decreasing ratio. increased also increasing time. On other hand, monochloroacetic accompanied enhancement in decrement E., while both...
Abstract Grafting of methyl methacrylate on cellulosic materials by chain transfer under the catalytic influence azobisisobutyronitrile (AIBN) was extensively studied. The graft yield is influenced reaction time, temperature, monomer and initiator concentration, medium nature substrate. In general, grafting shows an induction period after which polymerisation proceeds rapidly. increases decreases rising temperature from 50 to 70°C. This also case when concentration increased 2 6%. Increasing...
Abstract Graft polymerization of acrylamide (Aam) onto maize starch using potassium persulfate as initiator was investigated under different conditions including concentration and monomer, time temperature liquor ratio. Based on the results obtained, appropriate for grafting were established. These also used other monomers starch. Results obtained indicate that acquires highest graft ability while acrylic acid least, acrylonitrile methacrylic in between. The water solubility both nitrogen‐...
A number of different B cell subsets have been shown to exhibit regulatory activity using a variety mechanisms attenuate inflammatory diseases. Here we show, anti-CD20-mediated partial depletion in mice, that population mature cells distinguishable by IgDlow/- expression maintains tolerance by, at least part, promoting CD4+Foxp3+ T homeostatic expansion via glucocorticoid-induced tumor necrosis factor receptor ligand, or GITRL. Cell surface phenotyping, transcriptome analysis and...
Abstract Reaction of starch with acrylamide was carried out under different conditions including reaction medium, catalyst, concentration, time and temperature as well liquor ratio. Organic solvents, namely, isopropyl alcohol, dimethylformamide cyclohexane alone in admixture water at ratios were used medium. Catalysts include sodium hydroxide, trisodium phosphate, carbonate, benzoate, acetate formate. Acrylamide concentration ranged from 25% to 200%, based on weight starch. The studied over...
Abstract Research was designed to tailor polymeric materials for specific utilization, namely sizing of cotton textiles by making use maize starch and rice starch. Hence both starches were subjected independently oxidation with potassium persulphate obtain different molecular sizes. The original the oxidized then partially carboxymethylated monochloroacetic acid under catalytic influence sodium hydroxide. In this way structure starch, i.e., weight backbone substituents present thereon, could...
Abstract When starch was treated with KMnO 4 solution, MnO 2 deposited overall the starch. The amount of relied on concentration. Subjecting ‐containing to a solution consisting monomer (methacrylic acid, MAA) and acid (citric, tartaric, oxalic or sulphuric acid) resulted in formation poly(MAA)‐starch graft copolymer. magnitude grafting, expressed as meq. ‐COOH/100 g starch, determined by deposited, MAA concentration, temperature duration polymerization well kind concentration acid....
Abstract The feasibility of potassium permanganate to induce graft polymerization vinyl monomers onto nylon 6 was investigated. yield is greatly enhanced by increasing the monomer concentration, reaction time, and temperature. addition metallic ions as promoters grafting medium accelerates polymerization. A mechanism for proposed. activation energy initiation E i methyl methacrylate calculated found be 5 kcal/mole. overall rate R p depends on concentration.
Abstract Six types of cationic starch derivatives were prepared. These (1) containing primary, secondary, and tertiary amino groups quaternary ammonium salt (2) etherified grafted derivatives. treated with three dyes, an acid dye, a hydrolyzed reactive direct dye. Different factors affecting the dye sorption value (mmol/100 g sample) been studied. pH medium, treatment time, amine type, content, type molecular size, distance between groups. The efficiency percentage determined. increased...
Abstract Graft polymerization of acrylamide onto rice starch was investigated under different conditions using potassium persulphate, benzoyl peroxide or permanganate as initiator. This has led to establishment the most appropriate grafting for each these initiators. Under characterized by two rates regardless initiator used. The first rate occurred during initial stages while second later stages. three initiators were very close indicating insignificant effect nature on reaction. On other...
Poly(methyl acrylate)-starch graft copolymer was treated with sodium hydroxide. The influence of hydroxide concentration, reaction temperature and duration treatment were studied. extent hydrolysis assessed by estimating acrylic acid, methyl acrylate total polymer content before after treatment. It found that the increase in acid is equal to decrease on using concentration up 1 N, while higher leads a difference amount groups formed content. This depended duration. optimum condition gave...
Abstract The presence of nylon 66 during polymerization methyl methacrylate (MMA) under the influence azobisisobutyronitrile (AIBN) produces a nylon‐PMMA graft copolymer. copolymerization reaction is greatly influenced by medium, temperature and time reaction, concentration MMA, addition metallic ions. Polymerization in pure organic solvents brings about little or no grafting. Incorporation water into system enhances grafting significantly. A medium water/solvent mixture ratio 75:25...