- Reproductive Biology and Fertility
- Ovarian function and disorders
- Endometriosis Research and Treatment
- Uterine Myomas and Treatments
- Ovarian cancer diagnosis and treatment
- Cancer Risks and Factors
- Gynecological conditions and treatments
- Ectopic Pregnancy Diagnosis and Management
- Maternal and Perinatal Health Interventions
- Assisted Reproductive Technology and Twin Pregnancy
- Reproductive System and Pregnancy
- Acute Lymphoblastic Leukemia research
- Endometrial and Cervical Cancer Treatments
- Pelvic and Acetabular Injuries
- Reformation and Early Modern Christianity
- Intracerebral and Subarachnoid Hemorrhage Research
- Flow Measurement and Analysis
- Pediatric Urology and Nephrology Studies
- Delphi Technique in Research
- Childhood Cancer Survivors' Quality of Life
- Sepsis Diagnosis and Treatment
- Cerebral Venous Sinus Thrombosis
- Pituitary Gland Disorders and Treatments
- Colorectal Cancer Screening and Detection
- Diabetic Foot Ulcer Assessment and Management
Royal Hospital for Women
2016-2024
UNSW Sydney
2017-2023
University of California, San Francisco
2021
Reproductive Science Center
2021
Royal Prince Alfred Hospital
2013-2016
Fundación Chile
1958
To report the complication rate associated with external cephalic version (ECV) at term.Single-centre retrospective study.A major tertiary hospital in Sydney, Australia.All women who underwent an ECV Royal Prince Alfred Hospital from 1995-2013 were included.ECV was attempted on all consenting a breech presentation term absence of contraindications. Complications classified as minor (transient cardiotocography abnormalities, ruptured membranes, small antepartum haemorrhage) or serious (fetal...
Abstract STUDY QUESTION Is circulating cell-free DNA (cirDNA) from the endometrium elevated during menstruation and in endometriosis? SUMMARY ANSWER Endometrial cirDNA does not increase is endometriosis. WHAT IS KNOWN ALREADY Changes associated with common benign conditions are a potential source of false positives cancer diagnostic applications, but also present an opportunity for biomarker development diseases such as Elevated has been reported endometriosis patients compared to healthy...
Oocyte-secreted growth differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15) are critical paracrine regulators of female fertility. Recent studies demonstrated that serum concentrations associated with the number oocytes retrieved during IVF, therefore potential clinical use as biomarkers. However, it is unknown if presence endometriosis affects GDF9 or BMP15. An exploratory case-control study was prospectively performed on 60 women who underwent laparoscopy between April...
Background Salpingectomy may damage ovarian reserve by direct vascular interruption to the ovary or thermal injury from electrosurgery. It is plausible that this risk increase in context of salpingectomy conducted for ectopic pregnancy due distension fallopian tube and changes associated with pregnancy. Aim To report anti‐Müllerian hormone (AMH) concentrations before after laparoscopic as an indicator change reserve. Materials Methods Women aged 18–44 years scheduled tubal were prospectively...
( BJOG . 2017;124(5):767–772) There has been substantial debate regarding the most appropriate mode of delivery for a term breech baby. The Term Breech Trial (2000) found significantly lower perinatal and neonatal mortality as well serious morbidity in planned cesarean-section group compared with vaginal-birth group. As result this study, developed countries infants is now mainly by elective cesarean section. From maternal standpoint, however, section associated increased longer recovery...
Abstract Hysterosalpingo contrast sonography (HyCoSy) is a commonly performed procedure in the investigation of infertility. Infection an uncommon complication this procedure. Should it occur, generally mild and amenable to outpatient treatment with oral antibiotics. We present case immunosuppressed woman who underwent HyCoSy for secondary infertility developed life‐threatening sepsis Group A streptococcus.
A 35 year old woman underwent a HyCoSy for investigation of secondary infertility. It showed patent fallopian tubes. She had psoriatic arthritis which she received fortnightly Humira (TNF-blocker) injections and been trying to conceive 18 months. 3 days after the presented hospital with symptoms signs peritonitis confirmed by CT ultrasound imaging. Her temperature was 40.2C, tachycardic mildly hypotensive. Investigations revealed renal failure, increased inflammatory markers prolonged...
Chemotherapy predisposes people who menstruate to abnormal uterine bleeding that can be life-threatening and may also damage ovaries, resulting in premature menopause. The purpose of this study was explore the incidence menstrual history documentation counseling before, during, after cancer treatment.The medical charts 137 consecutive females (self-reported) aged 18 49 years receiving anticancer treatment at a major tertiary metropolitan hospital Australia between 2017 2020 were reviewed....
Abstract Background Chemotherapy is potentially harmful to a developing foetus, and there are limited data on the foetal impact of chemoimmunotherapy (CIT). Therefore, determining pregnancy status prior initiation CIT should be standard care. Aims To determine how many women childbearing age tested for immunochemotherapy administration. Methods A retrospective chart review at large Australian metropolitan cancer referral centre, including 304 aged 18–51 years with diagnosis receiving...
Background & Aims: Approximately 10% of patients have a sub-optimal response to controlled ovarian stimulation. Many different protocols for superovulation been developed this group but the optimal approach “poor responder” is yet be determined. Use corifollitropin alfa (Elonva) in flare (EF) protocol novel stimulation predicted poor responder patients. We hypothesised that unique pharmacokinetic and pharmacodynamic profiles would maximise FSH exposure follicular recruitment critical...
Background: Oocyte in vitro maturation (IVM) is a reproductive technology that generates mature oocytes from patients who have received minimal or no ovarian stimulation (OS). The minimal-stimulation feature of IVM makes it valuable option for cancer requiring fertility preservation (FP), before chemo- radiotherapy. When tissue collected cryopreservation (OTC), only the cortex preserved whereas medulla containing growing follicles discarded. To maximise future prospects patients, OTC should...