A5052815770- Yersinia bacterium, plague, ectoparasites research
- Animal Ecology and Behavior Studies
- Venomous Animal Envenomation and Studies
- Marine Invertebrate Physiology and Ecology
- Amphibian and Reptile Biology
- Physiological and biochemical adaptations
- Nicotinic Acetylcholine Receptors Study
- Connexins and lens biology
- Aquaculture Nutrition and Growth
- Reproductive biology and impacts on aquatic species
- Fish Ecology and Management Studies
- Animal Behavior and Reproduction
- Ion channel regulation and function
- Insect and Pesticide Research
- Coral and Marine Ecosystems Studies
- Parasite Biology and Host Interactions
- Genetic diversity and population structure
- Marine Toxins and Detection Methods
- Ichthyology and Marine Biology
- Marine Biology and Ecology Research
- Coastal wetland ecosystem dynamics
- Calpain Protease Function and Regulation
- Marine Ecology and Invasive Species
University of Lausanne
2024
SIB Swiss Institute of Bioinformatics
2024
Okinawa Institute of Science and Technology Graduate University
2017-2023
Most marine organisms have a biphasic life cycle during which pelagic larvae transform into radically different juveniles. In vertebrates, the role of thyroid hormones (THs) in triggering this transition is well known, but how morphological and physiological changes are integrated coherent way with ecological remains poorly explored. To gain insight question, we performed an analysis metamorphosis teleost, false clownfish (Amphiprion ocellaris). We show THs coordinate change color vision as...
Venoms are among the most biologically active secretions known, and commonly believed to evolve under extreme positive selection. Many venom gene families, however, have undergone duplication, often deployed in doses vastly exceeding LD50 for prey species, which should reduce strength of Here, we contrast these selective regimes using snake venoms, consist rapidly evolving protein formulations. Though decades extensive studies found that proteins subject strong selection, greater action...
Oral venom systems evolved multiple times in numerous vertebrates enabling the exploitation of unique predatory niches. Yet how and when they remains poorly understood. Up to now, most research on evolution has focused strictly toxins. However, using toxins present modern day animals trace origin system is difficult, since tend evolve rapidly, show complex patterns expression, were incorporated into arsenal relatively recently. Here we focus gene regulatory networks associated with...
Abstract Gene expression changes contribute to complex trait variations in both individuals and populations. However, the evolution of gene underlying traits over macroevolutionary timescales remains poorly understood. Snake venoms are proteinaceous cocktails where each toxin can be quantified mapped a distinct genomic locus traced for millions years. Using phylogenetic generalized linear mixed model, we analyzed data genes from 52 snake species spanning 3 venomous families estimated...
Key innovations provide ecological opportunity by enabling access to new resources, colonization of environments, and are associated with adaptive radiation. The most well-known pattern radiation is an early burst phenotypic diversification. Venoms facilitate prey capture widely believed be key leading However, few studies have estimated their evolutionary rate dynamics. Here, we test for patterns evolution in venom gene expression data from 52 venomous snake species. By identifying shifts...
Abstract Background Evolution can occur with surprising predictability when organisms face similar ecological challenges. For most traits, it is difficult to ascertain whether this occurs due constraints imposed by the number of possible phenotypic solutions or because parallel responses shared genetic and regulatory architecture. Exceptionally, oral venoms are a tractable model trait evolution, being largely composed proteinaceous toxins that have evolved in many tetrapods, ranging from...
Abstract Most marine organisms have a biphasic life cycle during which pelagic larva is transformed into radically different juvenile. In vertebrates the role of thyroid hormones (TH) in triggering this transition well known, but how morphological and physiological changes are integrated coherent way with ecological remains poorly explored. To gain insight question, we performed an integrative analysis metamorphosis teleost, clownfish Amphiprion ocellaris . We reveal TH coordinate change...
Abstract Teleosts are the most diverse group of vertebrates on earth. Their diversity is a testament to combined effects genetic, developmental, and evolutionary forces. However, disentangling interactions between these forces challenging due complexity genotype-phenotype relationship masking adaptive genetic signals by noise. Estimates molecular convergence where changes in sequence protein-coding genes lead identical amino acid substitution across multiple lineages provide strong evidence...
Abstract Venom is a widespread secretion in nature, extensively studied for its toxin components and application potential. Yet, the evolution of venom production remains poorly understood. To address this question, we conducted comparative transcriptomics analysis oesophagus-associated glands marine predatory gastropods, among which cone snail gland represents pinnacle specialisation. We found that functional divergence specialisation was achieved through redistribution ancestral digestive...
Venom is a widespread secretion in nature, extensively studied for its toxin components and application potential. Yet, the evolution of venom production remains poorly understood. To address this question, we conducted comparative transcriptomics analysis oesophagus-associated glands marine predatory gastropods, among which cone snail gland represents pinnacle specialisation. We found that functional divergence specialisation was achieved through redistribution ancestral digestive functions...
Venom-secreting glands are highly specialised organs evolved throughout the entire animal kingdom to synthetise and secrete toxins for predation defence. Venom is extensively studied its toxin components application potential; yet, how animals become venomous remains poorly understood. systems therefore offer a unique opportunity understand molecular mechanisms underlying functional innovation. Here, we conducted multi-species multi-tissue comparative transcriptomics analysis of 12 marine...
Abstract Oral venom systems evolved multiple times in numerous vertebrates enabling exploitation of unique predatory niches. Yet how and when they remains poorly understood. Up to now, most research on evolution has focussed strictly the toxins. However, using toxins present modern day animals trace origin system is difficult, since tend evolve rapidly, show complex patterns expression, were incorporated into arsenal relatively recently. Here we focus gene regulatory networks associated with...
Abstract Gene expression changes contribute to complex trait variations in both individuals and populations. However, how gene influences of traits over macroevolutionary timescales remains poorly understood. Being comprised proteinaceous cocktails, snake venoms are unique that the each toxin can be quantified mapped a distinct genomic locus traced for millions years. Using phylogenetic generalized linear mixed model, we analysed data genes from 52 species spanning three venomous families,...
Most marine organisms have a biphasic life cycle during which pelagic larva is transformed into radically different juvenile. In vertebrates, the role of thyroid hormones (TH) in triggering this transition well known, but how morphological and physiological changes are integrated coherent way with ecological remains poorly explored. To gain insight question, we performed an integrative analysis metamorphosis teleost, clownfish Amphiprion ocellaris. We reveal TH coordinate change color vision...
Abstract Sea anemones in the order Anthozoa play an integral part marine ecosystems by providing refuge and habitat for various organisms. Despite this, much of their molecular ecology remains elusive. can nurture numerous symbiotic relationships; most iconic being one between giant sea anemonefish. However, genes biological processes associated with this symbiosis unknown. Additionally, it is unclear how mediate interactions anemones, anemonefish, symbionts from algal family Symbiodiniaceae...
Abstract Evolution can occur with surprising predictability when organisms face similar ecological challenges. How and why traits arise repeatedly remains a central question in evolutionary biology, but the complexity of most makes it challenging to answer. Reptiles mammals independently evolved oral venoms consisting proteinaceous cocktails that allow mapping between genotype phenotype. Although biochemically toxins as major venom components across many taxa, whether these via convergent or...