Sajal De

ORCID: 0000-0002-8349-125X
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About
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Research Areas
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Asthma and respiratory diseases
  • Respiratory Support and Mechanisms
  • Air Quality and Health Impacts
  • Pulmonary Hypertension Research and Treatments
  • SARS-CoV-2 and COVID-19 Research
  • Tracheal and airway disorders
  • Tuberculosis Research and Epidemiology
  • COVID-19 Clinical Research Studies
  • Inhalation and Respiratory Drug Delivery
  • Airway Management and Intubation Techniques
  • Diagnosis and treatment of tuberculosis
  • Heart Rate Variability and Autonomic Control
  • Disaster Response and Management
  • Foreign Body Medical Cases
  • Sarcoma Diagnosis and Treatment
  • Occupational exposure and asthma
  • Cardiovascular and exercise physiology
  • COVID-19 diagnosis using AI
  • Lung Cancer Diagnosis and Treatment
  • Obstructive Sleep Apnea Research
  • Ultrasound in Clinical Applications
  • Indoor Air Quality and Microbial Exposure
  • Cancer Diagnosis and Treatment
  • Head and Neck Surgical Oncology

All India Institute of Medical Sciences Raipur
2020-2025

KIIT University
2025

Creative Commons
2024

National Institute of Malaria Research
2020-2023

Indian Council of Medical Research
2023

Academy of Scientific and Innovative Research
2023

Gyeongsang National University
2023

National University College
2023

New Generation University College
2023

Ajou University
2023

Psychological impairment is a significant co-morbid condition of chronic obstructive pulmonary disease (COPD). No studies from India have been conducted to assess the prevalence depression in COPD.We investigated 100 consecutive stable COPD patients during their routine outpatient department visits. Patients diagnosed or systemic diseases were excluded. Severity was classified according Global Initiative for Chronic Obstructive Lung Disease (GOLD) guidelines. Hindi translations patient...

10.5005/ijcdas-53-1-35 article EN The Indian Journal of Chest Diseases and Allied Sciences 2022-06-10

The usual presentation of foreign body (FB) aspiration into the tracheobronchial tree is a choking sensation followed by recurrent respiratory symptoms. Without definitive history, diagnosis FB can be challenging. Here, we present case 40-year-old male who presented with episodes blood-stained sputum over past six years. Contrast-enhanced computed tomography chest and serological investigations suggested allergic bronchopulmonary aspergillosis. Video bronchoscopy was performed for hemoptysis...

10.7759/cureus.78280 article EN Cureus 2025-01-31

Background: Chest radiography is often the most utilized and primary investigation for patients with COVID-19 pneumonia, however, only limited studies are available evaluating its essence. Therefore, we retrospectively analyzed various chest radiographic patterns in correlated severity index clinical laboratory parameters. Methods: In this retrospective study, radiographs of 512 diagnosed pneumonia were assessed, out which 289 satisfying inclusion exclusion criteria recruited study. The...

10.7759/cureus.78942 article EN Cureus 2025-02-13

Tracheal stenosis following prolonged intubation is a relatively rare but serious problem. However, some degree of airway injury common intubation, no matter whether it or short duration. Here, we are reporting fifty six year old male patient who developed multiple web like tracheal with high volume low pressure cuff endotracheal tube. Subsequently, the was successfully dilated by balloon bronchoplasty.

10.4103/0972-5229.45081 article EN Indian Journal of Critical Care Medicine 2008-01-01

10.1016/j.rmed.2004.06.003 article EN publisher-specific-oa Respiratory Medicine 2004-07-23

Abstract Background The increasing trend of Chronic Obstructive Pulmonary Disease (COPD) in becoming the third leading cause deaths by 2020 is great concern, globally as well India. Dysregulation protease/anti-protease balance COPD has been reported to tissue destruction, inflammation and airway remodelling; which are peculiar characteristics COPD. Therefore, it imperative explore various serum proteases involved pathogenesis, candidate biomarkers. Asthma often have overlapping symptoms...

10.1186/s12890-020-01323-3 article EN cc-by BMC Pulmonary Medicine 2020-11-16

Extramedullary haematopoiesis associated with thalassaemia leading to spinal cord compression is an extremely rare event in the course of disease. The efficacy radiation therapy advocated management such a complication. Two patients thalassaemia, who had presented compression, were successfully treated by modest dose local radiotherapy. In one patients, however, radiotherapy was resorted after initial decompressive laminectomy and partial removal intraspinal haematopoietic mass proved...

10.1136/jnnp.55.4.310 article EN Journal of Neurology Neurosurgery & Psychiatry 1992-04-01

INTRODUCTION COVID-19 vaccination was launched in India on January 16, 2021. The for adults aged >60 years with or without comorbidities and 45−60 specified rolled out from March 1, Two vaccines—Covishield® Covaxin®, were only available during this period; however, the effects of partial immunization survival hospitalized patients not much known at that time. From end 2021, a sudden surge cases (second pandemic) noted across different parts India. This second pandemic probably due to highly...

10.4103/picr.picr_48_23 article EN cc-by-nc-sa Perspectives in Clinical Research 2024-01-01

Abstract The present study investigated two single nucleotide polymorphisms (SNPs)—rs479200 and rs516651 in the host EGLN1 / PHD2 gene for their association with COVID-19 severity. A retrospective cohort of 158 patients from Indian population (March 2020 to June 2021) was enrolled. Notably, frequency C allele (0.664) twofold higher than T (0.336) severe patients. Here, we report a novel finding that rs479200 imparts high risk (odds ratio—6.214 (1.84–20.99) p = 0.003; 9.421 (2.019–43.957)...

10.1186/s40246-024-00572-1 article EN cc-by Human Genomics 2024-01-30

The quality of sleep in chronic obstructive pulmonary disease (COPD) patient from India has not been studied. Aim this study was evaluation subjective assessment stable COPD patients and its relationship with associated depression.Forty clinically were recruited outpatient department their status classified as per Global Initiative for Chronic Obstructive Lung Disease guideline. Presence depression assessed by administering Patient Health Questionnaire (PHQ)-9 measured Pittsburgh Sleep...

10.4103/0970-2113.102808 article EN cc-by-nc-sa Lung India 2012-01-01

Lidocaine is commonly used for topical anaesthesia during fibreoptic bronchoscopy (FOB) and it can cause methaemoglobinemia. The present study was undertaken to evaluate the severity of post-bronchoscopy methaemoglobinemia while using lidocaine as a anaesthetic agent.We prospectively studied consecutive adult patients who underwent diagnostic FOB in our institution. Blood methaemoglobin levels were estimated by co-oximetry before one hour after first instillation lidocaine. Occurrence...

10.5005/ijcdas-53-4-211 article EN The Indian Journal of Chest Diseases and Allied Sciences 2022-06-10

Bronchoscopy is usually performed under sedation to improve patient comfort and willingness accept a repeat procedure. with low dose of does not necessarily comfort, overt may be dangerous for those preexisting lung diseases.The aim this study was evaluate the visual analogue scale cough, pain, nausea, choking sensation, overall discomfort level during flexible bronchoscopy without sedation. Acceptance requirement lidocaine procedure were also evaluated.We evaluated 70 consecutive patients...

10.1097/lbr.0b013e3181afca25 article EN Journal of Bronchology & Interventional Pulmonology 2009-07-01

Traffic-related air pollution (TRAP) is a major source of ambient in urban areas. Shopkeepers heavily trafficked roadside shops are persistently exposed to high levels TRAP.To estimate the prevalence respiratory morbidity shopkeepers areas Bhopal city (India) and determine any association with long term exposure TRAP.This cross-sectional study was conducted among 251 working three traffic corridors city. The demographic profile were collected by administering validated questionnaire. total...

10.5696/2156-9614-9.21.190305 article EN cc-by Journal of Health and Pollution 2019-03-01

Forced oscillation technique (FOT) is a to measure the mechanical properties of lung. The present study was aimed develop regression equations within- and whole-breath respiratory impedance (Zrs) healthy Indian adults.Total 323 adults were sequentially screened. Smokers, individuals with symptoms or diseases, unable perform acceptable FOT excluded. Within- resistance (Rrs) reactance (Xrs) measured at 5, 11, 19 Hz by Resmon Pro® Full device. Rrs Xrs generated separately for men women multiple...

10.4103/lungindia.lungindia_260_19 article EN cc-by-nc-sa Lung India 2019-12-31

Background The nucleocapsid protein (N protein) of SARS-CoV-2 is undeniably a potent target for the development diagnostic tools due to its abundant expression and lower immune evasion pressure compared spike (S) protein. Methods Blood samples active COVID-19 infections (n=71) post-COVID-19 (n=11) were collected from tertiary care hospital in India; pre-COVID-19 (n=12) sera served as controls. Real-time reverse transcriptase-PCR (rRT-PCR) confirmed pooled (n=5) used with PEPperCHIP® Proteome...

10.7759/cureus.34827 article EN Cureus 2023-02-10

The involvement of respiratory system due to inhalation methyl isocyanate (MIC) during Bhopal gas disaster was particularly severe. We retrospectively evaluated the annual changes in spirometric parameters among those who were affected this (exposed survivors) and had symptoms.Spirometry reports exposed survivors that carried out our institution reviewed we identified 252 subjects performed spirometry at least twice with interval more than one year. indices them calculated.The average age...

10.4103/0970-2113.110414 article EN cc-by-nc-sa Lung India 2013-01-01
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