A5006420656- Advanced MRI Techniques and Applications
- Cardiovascular Function and Risk Factors
- Advanced X-ray and CT Imaging
- Cardiac Imaging and Diagnostics
- Kidney Stones and Urolithiasis Treatments
- Pulmonary Hypertension Research and Treatments
- Atomic and Subatomic Physics Research
- Advanced X-ray Imaging Techniques
- Radiation Dose and Imaging
- Pediatric Urology and Nephrology Studies
- Tryptophan and brain disorders
- Attention Deficit Hyperactivity Disorder
- Gut microbiota and health
- Prostate Cancer Diagnosis and Treatment
- MRI in cancer diagnosis
- Medical Imaging Techniques and Applications
- Cardiac Valve Diseases and Treatments
- Lung Cancer Diagnosis and Treatment
- Schizophrenia research and treatment
- Prostate Cancer Treatment and Research
- Ultrasound Imaging and Elastography
- Medical Imaging and Analysis
- Ultrasound in Clinical Applications
- Hemodynamic Monitoring and Therapy
- Probiotics and Fermented Foods
Örebro University
2014-2024
Karolinska University Hospital
2024
Karolinska Institutet
2024
Örebro University Hospital
2002-2014
Linköping University
1994-2005
The aim of this study was to evaluate commercial metal artefact reduction (MAR) techniques in X-ray CT imaging hip prostheses.Monoenergetic reconstructions dual-energy (DECT) data and several different MAR algorithms, combined with single-energy or DECT, were evaluated by a bilateral prosthesis phantom. images compared uncorrected based on number accuracy noise regions interest.The three algorithms studied implied general (up 67%, 74% 77%) an improvement accuracy, both close the prostheses...
Computed tomography (CT) is the method of choice for diagnosing ureteral stones - kidney that obstruct ureter. The purpose this study to develop a computer aided detection (CAD) algorithm identifying stone in thin slice CT volumes. challenge CAD urinary lies similarity shape and intensity with non-stone structures how efficiently deal large high-resolution We address these challenges by using Convolutional Neural Network (CNN) works directly on high resolution evaluated data base 465...
Purpose To evaluate two commercial CT metal artifact reduction ( MAR ) algorithms for use in proton treatment planning the head and neck (H&N) area. Methods An anthropomorphic phantom with removable metallic implants (dental fillings or implant) was ‐scanned to O‐MAR (Philips) iMAR (Siemens) algorithms. Reference images were acquired without any place. Water equivalent thickness WET calculated different path directions compared between image sets. Images also evaluated parotid, tonsil,...
Abstract The objectives were to develop and validate a Convolutional Neural Network (CNN) using local features for differentiating distal ureteral stones from pelvic phleboliths, compare the CNN method with semi-quantitative radiologists’ assessments evaluate whether assessment of calcification its surroundings is sufficient discriminating phleboliths in non-contrast-enhanced CT (NECT). We retrospectively included 341 consecutive patients acute renal colic stone on NECT showing either stone,...
Probiotics can alter brain function via the gut-brain axis. We investigated effect of a probiotic mixture containing Bifidobacterium longum, Lactobacillus helveticus and Lactiplantibacillus plantarum. In randomized, placebo-controlled, double-blinded crossover design, 22 healthy subjects (6 m/16 f; 24.2 ± 3.4 years) underwent four-week intervention periods with probiotics placebo, separated by washout period. Voxel-based morphometry indicated that affected gray matter volume cluster covering...
Probiotics are suggested to impact physiological and psychological stress responses by acting on the gut-brain axis. We investigated if a probiotic product containing Bifidobacterium longum R0175, Lactobacillus helveticus R0052 Lactiplantibacillus plantarum R1012 affected processing in double-blinded, randomised, placebo-controlled, crossover proof-of-concept study (NCT03615651). Twenty-two healthy subjects (24.2 ± 3.4 years, 6 men/16 women) underwent placebo intervention for 4 weeks each,...
Abstract The purpose of this study was to evaluate the accuracy and reproducibility phase contrast imaging using sensitivity encoding (SENSE) method at different reduction factors. Analytical expressions were derived that state how is influenced for velocity flow measurements. Computer simulations, in vitro vivo studies performed order validate these assess affected when factors are applied. It shown depends on geometry Since factor varies spatially, so does imaging. In areas with high...
In this paper, we introduce a method for identification of bacteria in human blood culture samples using an electronic nose. The uses features, which capture the static (steady state) and dynamic (transient) properties signal from gas sensor array proposes means to ensemble results consecutive samples. underlying mechanism ensembling is based on estimation posterior probability, extracted support vector machine classifier. A large dataset representing ten different cultures has been used...
To compare the assessment of patients with multiple sclerosis (MS) using synthetic and conventional MRI. Synthetic axial images were prospectively acquired for 52 diagnosed MS. Quantitative MRI (qMRI) was used measuring proton density relaxation times (T1, T2) then, based on these parameters, T1W, T2W FLAIR calculated. Image stacks reviewed blindly, independently in random order by two radiologists. The number location all lesions documented categorised. A combined report lesion load...
To evaluate metal artefact reduction (MAR) techniques from four CT vendors in hip prosthesis imaging.Bilateral phantom images, obtained by using MAR algorithms for single-energy data or dual-energy (DECT) and monoenergetic reconstructions of DECT data, were visually graded five radiologists 10 image quality criteria. Comparisons between the images a reference performed each scanner separately. Ordinal probit regression analysis was used.The general improved based on majority criteria (up to...
Evidence from preclinical studies suggests that probiotics affect brain function via the microbiome-gut-brain axis, but evidence in humans remains limited.The present proof-of-concept study investigated if a probiotic product containing mixture of Bifidobacterium longum R0175, Lactobacillus helveticus R0052 and Lactiplantibacillus plantarum R1012 (in total 3 × 109 CFU/day) affected functional responses healthy subjects during an emotional attention task.In this double-blinded, randomized,...
Abstract Aims To describe patients' experiences of magnetic resonance examination the liver and their two breath‐hold techniques. Background Traditionally, patients are instructed by radiographer to hold breath during examination. Alternatively, patient can initiate start image acquisition. Studies have revealed that examinations be experienced as challenging. Design Descriptive qualitative. Methods Semi‐structured interviews were conducted with 28 analysed using qualitative content...
Purpose To develop, and evaluate the performance of, a deep learning‐based three‐dimensional (3D) convolutional neural network (CNN) artificial intelligence (AI) algorithm aimed at finding needles in ultrasound images used prostate brachytherapy. Methods Transrectal (TRUS) image volumes from 1102 treatments were to create clinical ground truth (CGT) including 24422 individual that had been manually digitized by medical physicists during brachytherapy procedures. A 3D CNN U‐net with 128 ×...
The role of inflammation in the aetiology schizophrenia has gained wide attention and research on association shows an exponential growth last 15 years. Autoimmune diseases severe infections are risk factors for later development schizophrenia, elevated inflammatory markers childhood or adolescence associated with a greater adulthood, individuals have increased levels pro-inflammatory cytokines compared to healthy controls, autoimmune overrepresented schizophrenia. However, treatments...
Time resolved three-dimensional (3D) echocardiography generates four-dimensional (3D+time) data sets that bring new possibilities in clinical practice. Image quality of (4D) is however regarded as poorer compared to conventional where time-resolved 2D imaging used. Advanced image processing filtering methods can be used achieve improvements but the cost heavy processing. The recent development graphics unit (GPUs) enables highly parallel general purpose computations, considerably reduces...
Abstract Objectives To prospectively validate three quantitative single-energy CT (SE-CT) methods for classifying uric acid (UA) and non-uric (non-UA) stones. Methods Between September 2018 2019, 116 study participants were included in the if they had at least one 3–20-mm urinary stone on an initial tract SE-CT scan. An additional dual-energy (DE-CT) scan was performed, limited to of interest. Additionally, include a sufficient number UA stones, eight with confirmed DE-CT retrospectively...
Using 3D image-guided adaptive brachytherapy for cervical cancer treatment, it often means that patients are transported and moved during the treatment procedure. The purpose of this study was to determine intra-fractional longitudinal applicator shift in relation high risk clinical target volume (HR-CTV) by comparing geometries at imaging dose delivery with without needles.Measurements were performed 33 (71 fractions), where 25 fractions 46 interstitial needles. Gold markers placed lower...
There is today no established approach to estimate right ventricular ejection fraction (RVEF) using 2D transthoracic echocardiography (TTE). The aim of this study was evaluate a new method for RVEF calculations TTE and compare the results with cardiac magnetic resonance (CMR) imaging tricuspid annular plane systolic excursion (TAPSE).A total 37 subjects, 25 retrospectively included patients twelve healthy volunteers, were give wide range RVEF. ventricle (RV) modeled as part an ellipsoid...
The standard imaging procedure for a patient presenting with renal colic is unenhanced computed tomography (CT). CT measured size has close correlation to the estimated prognosis spontaneous passage of ureteral calculus. Size estimations urinary calculi in images are still based on two-dimensional (2D) reformats.To develop and validate calculus oriented three-dimensional (3D) method measuring length width compare measurements corresponding 2D obtained axial coronal reformats.Fifty...
Background Magnetic resonance imaging (MRI) is useful in the diagnosis of clinically significant prostate cancer (csPCa). MRI-derived radiomics may support csPCa. Purpose To investigate whether adding from biparametric MRI to predictive models based on clinical and parameters improves prediction csPCa a multisite-multivendor setting. Material Methods Clinical information (PSA, PSA density, volume, age), reviews (PI-RADS 2.1), (histogram texture features) were retrieved prospectively included...