A5044372572- Traumatic Brain Injury and Neurovascular Disturbances
- Neurosurgical Procedures and Complications
- Spinal Fractures and Fixation Techniques
- Spine and Intervertebral Disc Pathology
- Head and Neck Surgical Oncology
- Intracerebral and Subarachnoid Hemorrhage Research
- Cerebrospinal fluid and hydrocephalus
- Meningioma and schwannoma management
- Trauma and Emergency Care Studies
- Acute Myeloid Leukemia Research
- Chronic Myeloid Leukemia Treatments
- Hematopoietic Stem Cell Transplantation
- Spinal Hematomas and Complications
- Glioma Diagnosis and Treatment
- Intracranial Aneurysms: Treatment and Complications
- Traumatic Brain Injury Research
- Infectious Diseases and Tuberculosis
- Neurofibromatosis and Schwannoma Cases
- Chronic Lymphocytic Leukemia Research
- Traumatic Ocular and Foreign Body Injuries
- Lymphoma Diagnosis and Treatment
- Vasculitis and related conditions
- Trauma Management and Diagnosis
- Cervical and Thoracic Myelopathy
- Acute Ischemic Stroke Management
Wonkwang University
2012-2024
Data Management (Italy)
2024
Yeouido St. Mary's Hospital
2011
Catholic University of Korea
2004-2010
Pain Management Institute
2010
Berberine has a wide range of biochemical and pharmacologic effects, including antitumor activity, but the mechanisms involved in berberine-induced apoptosis remain unclear. The purpose present study was to investigate changes oxidative stress endoplasmic reticulum (ER)-related molecules, which are closely associated with cell death-signaling transduction pathways, human glioblastoma T98G cells treated berberine. significantly decreased viability dose-dependent manner. increased production...
The aims of the Korean Neuro-Trauma Data Bank System (KNTDBS) are to evaluate and improve treatment outcomes for brain trauma, prevent provide data research. Our purpose was examine mortality rates following traumatic injury (TBI) in a retrospective study investigate sociodemographic variables, characteristics, causes TBI-related death based on from KNTDBS.From 2010 2014, we analyzed 2617 patients registered KNTDBS. demographic characteristics with TBI were investigated. We divided into 2...
To investigate the correlation of trough imatinib mesylate (IM) levels with cytogenetic or molecular responses, we measured IM in patients chronic myeloid leukemia, phase (CML-CP), at 6 months treatment a standard dose IM. Eighty-seven newly diagnosed CML-CP were prospectively enrolled. Seventy-eight (89.7%) showed an optimal response (complete partial response) months. Trough 1378 ± 725 ng/mL. When categorized into two groups, there was statistically significant difference numbers and...
To verify the feasibility of 800 cGy total body irradiation (TBI) with 120 mg/kg cyclophosphamide (TBI-800/Cy-120) as a conditioning regimen for unrelated stem cell transplantation (u-SCT) in adult patients severe aplastic anemia, we analyzed 50 consecutive who underwent u-SCT, including 26 from our previous pilot study. Seventeen received transplants mismatched donors via high-resolution DNA typing (8 8). Thirty-eight bone marrow and 12 peripheral blood cells (PBSCs). Graft-versus-host...
Although traumatic brain injury (TBI) occurs in people of all age groups, the elderly population is at a particular risk. The proportion society markedly increasing and Korea one most rapidly aging societies. Here, we analyzed data from 904 patients older over 65 years who were registered Korean Neuro-Trauma Data Bank System (KNTDBS).The Society Neurotraumatology recorded 20 institutions between September 2010 March 2014. This retrospective study examined clinical epidemiology, sex...
Patients' gender, which can be one of the most important determinants traumatic brain injury (TBI) outcomes, is also likely to interact with many other outcome variables TBI. This multicenter descriptive study investigated gender differences in epidemiological, clinical, treatment, mortality, and variable characteristics adult TBI patients. The selection criteria were defined as patients who had been diagnosed admitted hospital between January 1, 2016 December 31, 2018. A total 4468 enrolled...
We report the case of a 78-year-old man with chronic subdural haematoma (CSDH) who presented impairment in recent memory and gait disturbance. He underwent burr-hole craniostomy closed-drainage system. A computed tomography scan conducted on postoperative day 3 demonstrated an acute epidural over contralateral frontoparietal convexity. Craniotomy evacuation were immediately performed. The was located between outer inner dura mater that each comprise single layer. To our knowledge, this is...
Acute epidural hematoma (AEDH) occurring as a result of traumatic head injury constitutes one the most critical emergencies in neurosurgery. However, there are only several reports that show rapid disappearance AEDH without surgical intervention. We suggest redistribution through overlying skull fractures mechanism AEDH. A 13-year-old female fell from height about 2 m and presented with mild headache. computed tomography (CT) scan performed 4 hours after revealed an fracture right temporal...
Occipital neuralgia is usually defined as paroxysmal stabbing pain in the greater or lesser occipital nerve (GON LON) distribution. In patients, surgical considerations are carefully taken into account if medical management ineffective. However, identification of artery by palpation patients with thick necks small arteries can be technically difficult. Therefore, we established a new technique using transcranial Doppler (TCD) sonography for more accurate and rapid identification. The patient...
The authors report a case of 42-year-old woman with an intraventricular tumor in the trigone left lateral ventricle.The first operation achieved microscopically complete resection.The was histologically atypical meningioma.After 26 months, there were recurrences meningioma.Complete resection and adjuvant radiation therapy performed, histological diagnosis malignant meningioma.Sixteen months after second operation, spinal metastasis cervicolumbar lesion diagnosed subtotal removal cervical...
Myeloid sarcoma is a solid, extramedullary tumor composed of leukemic myeloblasts or immature myeloid cells. Intraparenchymal without the involvement skull meninges extremely rare. Here, we present case 49-year-old man who developed intraparenchymal on left cerebellum after allogeneic bone marrow transplantation (BMT). He received radiotherapy complete removal sarcoma, but he was diagnosed spinal three month later. Nine months operation, new intracranial and were patient's condition had been...
The objective of this study was to compare the magnetic resonance (MR) imaging tuberculous spondylitis with pyogenic spondylitis.MR images spines 41 patients infectious at our institution over 8-years period were retrospectively reviewed. Eighteen infective excluded because their results on marrow biopsy and culture negative. MR findings in 6 (3 male, 3 female) compared those 17 (10 7 spondylitis.Two statiscally significant differentiating from spondylitis: a well defined paraspinal abnormal...
Introduction: Intracranial subdural empyema (ISDE) is a life-threatening intracranial infection. Early and precise detection, timely surgery, appropriate antibiotic therapy are the keys to more favorable clinical outcome. Treatment aimed at complete evacuation of eradication source However, in case elderly patients or with poor health, doctors hesitate perform open cranial surgery under general anesthesia; thus, choice surgical method fraught many limitations.
Background: The risks associated with percutaneous vertebroplasty (PV) are low. Patients show marked improvement and able to rapidly resume normal activities after PV. sudden development of postoperative vertebral compression fracture (VCF) is a common complication, additional PV frequently performed in these cases. However, there have been no studies reporting acute fractures an adjacent vertebra immediately Objective: This case report presents rare which the patient had undergo second...
Traditionally, staged surgery has been preferred in the treatment of compound comminuted depressed fracture (FCCD) after traumatic brain injury (TBI) and involves removal primarily damaged bone subsequent cranioplasty. The main reason for delayed cranioplasty was to reduce risk infection-related complications. Here, author performed immediate reconstruction using a titanium mesh consecutive patients with FCCD TBI, reported surgical results, reviewed previous studies. Nineteen who underwent...