Mesenchymal stem cells (MSCs) are multipotent progenitor with the ability to secrete growth factors. Because wound healing is associated fibroblast and extracellular matrix (ECM) in dermis epidermis, we used resolve question of whether or not MSCs regulate vitro via a regenerative function. Using cell proliferation assay, demonstrated that conditioned media (CM) obtained from significantly enhanced survival cells. Moreover, by measurement mRNA protein, observed CM also promoted production...

Objective Chronic subdural hematoma (cSDH) is common condition in neurosurgical field. It difficult to select the treatment modality between surgical method and conservative when patients have no or mild symptoms. The purpose of this study provide a suggestion that could be cured with modality. Methods We enrolled 16 who had received for cSDH without special medications which affect resolution such as mannitol, steroids, tranexamic acid angiotensin converting enzyme inhibitors. were...

Cerebral vasospasm still remains a major cause of the morbidity and mortality, despite developments in treatment aneurysmal subarachnoid hemorrhage. The authors measured utility benefits external lumbar cerebrospinal fluid (CSF) drainage to prevent clinical its sequelae after endovascular coiling on hemorrhage this randomized study.Between January 2004 March 2006, 280 patients with were treated at our institution. Among them, 107 met study criteria. group consisted 47 who underwent CSF...

The aims of the Korean Neuro-Trauma Data Bank System (KNTDBS) are to evaluate and improve treatment outcomes for brain trauma, prevent provide data research. Our purpose was examine mortality rates following traumatic injury (TBI) in a retrospective study investigate sociodemographic variables, characteristics, causes TBI-related death based on from KNTDBS.From 2010 2014, we analyzed 2617 patients registered KNTDBS. demographic characteristics with TBI were investigated. We divided into 2...

Primary intraosseous meningioma is a rare tumor, and atypical pathologic components both osteolytic lesion dura soft tissue invasion extremely rare. A 65-year-old woman presented with 5-month history of mass on the right frontal area. MR imaging revealed 4 cm sized, multilobulated, strongly-enhancing bone, CT showed destructive skull lesion. The was adhered tightly to scalp mater, it extended some part outer inner dural layers without brain invasion. extradural were totally removed...

To survey the microbiological contamination of laboratory mice and rats in Korea during a 5-year period, we monitored animals housed mouse rat facilities with either barrier or conventional systems. At facilities, most important pathogen identified was hepatitis virus (MHV), while Mycoplasma pulmonis at facilities. Interestingly, hantavirus recovered from both The common protozoon Tritrichomonas muris Entamoeba In addition, found that severe. These results suggest should be renovated...

GBM is the most common primary brain tumor, but intraventricular rare and only few cases have been reported in literature.The authors report a case of 64-year-old man who had remote history previous periventricular intracerebral hemorrhage.Brain computed tomography (CT) magnetic resonance (MR) imaging showed an lesion with inhomogeneous enhancement, infiltrative borders necrotic cyst, obstructive hydrocephalus.The patient underwent surgical removal through transcortical route via bottom...

Perineurial cysts (Tarlov cysts) are lesions of the nerve root that often observed in sacral area. There is debate about whether symptomatic perineurial should be treated surgically. We presented three patients with cyst who were surgically, and introduced recapping laminectomy. Patients complained low back pain hypesthesia on lower extremities. performed operations technique for all three. The outcome measure was baseline visual analogue score post operative follow up magnetic resonance...

Clear cell ependymoma was included in the World Health Organization classification of nervous system 1993, and all reported cases, except for two spinal cord, were located brain, mainly supratentorial compartment. Astrocytomas outnumber ependymomas entities partly share cytologic findings such as long, bipolar glial processes oval to round nuclei resembling those seen pilocytic astrocytoma. Here, we report first Korean case intramedullary clear which is third situated cord literature. The...

Surgical elevation of the depressed bone is known to be conventional treatment usually recommended for a simple skull fracture in adult or pediatric age. The authors introduce, however, case an infant which was elevated by means cup breast pump and suction generator without surgical elevation. In our case, surgery, 'cup-shaped' safely with no neurological signs. This method considered simple, effective, safe, alternative procedure fracture.

<i>Background:</i> Previous data about the prevalence of coronary artery disease in dialysis patients were mainly based on history or electrocardiogram. <i>Methods:</i> We evaluated using routine thallium-201 single photon emission computed tomography (SPECT) 227 at start chronic peritoneal between January 1996 and October 2003. also analyzed its association with mortality. <i>Results:</i> Fifty-one (22.5%) positive thallium SPECT. There significant...

We describe two cases of vertebral artery injury during posterior cervical fusion. treated both by an endovascular technique. The may result in catastrophic situations, such as, infarction, massive blood loss and even death. Our clinical outcome was good we prove that treatment is effective less invasive way to treat injury.

Among posterior circulation aneurysms, basilar tip aneurysm is the most difficult to treat. Because of their deep location in front brainstem and intimate relationship perforating vessels, morbidity mortality rates associated with direct exposure used be daunting. Complex intracranial aneurysms are not uncommonly encountered cerebrovascular practice. Often complexity can render standard treatment either impossible or exceedingly hazardous. Although endovascular therapy an available...

Uncontrolled cerebrospinal fluid (CSF) leakage after transsphenoidal surgery (TSS) for pituitary adenoma can lead to meningitis. Intracranial mycotic pseudoaneurysm is a rare complication in central nervous system infection. Large single more uncommon. Most aneurysms occur due endocarditis. The present patient had no heart problem and was infected by CSF surgery. We case of large ruptured as cerebral infection TSS macroadenoma. Key Words: aneurysm · Transsphenoidal Pituitary

2038 Background: Glioblastoma (GBM) is an incurable cancer. Patients are subjected to inevitable death by recurrence after the standard treatment, temozolomide (TMZ) and irradiation. Having tumor-initiating ability, GBM cancer stem cells (GSCs) resist therapy give rise recurrent tumors; however, no GSC-targeted treatment has proven its efficacy in clinical trials. Therefore, we sought discover vulnerability of GSCs develop a novel targeted combine with TMZ, which will enable complete without...

A primary fibroxanthoma of the central nervous system is very rare. We present a case an infantile that arose from cranial dura mater in six-month-old girl with US, MRI and PET/CT features mimicked meningioma. The tumor appeared as large, well-circumscribed echogenic mass right parieto-occipital area on US. was seen isoattenuated to slightly hypoattenuated pre-contrast CT scan hypometabolic PET/CT. As T2-weighted image, heterogeneously hyperintense gray matter. isointense T1-weighted image...