A5010188898- SARS-CoV-2 and COVID-19 Research
- COVID-19 epidemiological studies
- Viral Infections and Outbreaks Research
- COVID-19 Digital Contact Tracing
- Health Systems, Economic Evaluations, Quality of Life
- Childhood Cancer Survivors' Quality of Life
- Metabolism and Genetic Disorders
- COVID-19 Pandemic Impacts
Brown University
2022-2024
Mathematical and statistical models are used to predict trends in epidemic spread determine the effectiveness of control measures. Automatic regressive integrated moving average (ARIMA) for time-series forecasting, but only few 2019 coronavirus disease (COVID-19) pandemic have incorporated protective behaviors or vaccination, known be effective control. To improve accuracy prediction, we applied newly developed ARIMA with predictors (mask wearing, avoiding going out, vaccination) forecast...
Taiwan was a coronavirus disease 2019 (COVID-19) outlier, with an extraordinarily long transmission-free record: 253 days without locally transmitted infections while the rest of world battled wave after infection. The appearance alpha variant in May 2021, closely followed by delta variant, disrupted this streak. However, despite low vaccination coverage (<1%), outbreaks were well-controlled. This study analyzed time to border closure and conducted one-sample t test compare between...
This modeling study considers different screening strategies, contact tracing, and the severity of novel epidemic outbreaks for various population sizes, providing insight into multinational containment effectiveness emerging infectious diseases, prior to vaccines development. During period ancestral SARS-Cov-2 virus, tracing alone is insufficient achieve outbreak control. Although universal testing proposed in multiple nations, its accompanied by other measures rarely examined. Our research...
Clinical trials are an essential aspect of the drug development process. endpoints and surrogate two terms used in clinical to measure effectiveness a treatment. While typically require higher costs longer durations observation show direct benefits, have been introduced as cheaper faster method that may be predict effects. When there is linear relationship between endpoint, still need rule out threshold corresponds no benefit. The determination such uses knowledge numerous parameters...