A5026611713- Sinusitis and nasal conditions
- Head and Neck Cancer Studies
- Head and Neck Surgical Oncology
- Reconstructive Surgery and Microvascular Techniques
- Tracheal and airway disorders
- Nasal Surgery and Airway Studies
- Nasolacrimal Duct Obstruction Treatments
- Salivary Gland Tumors Diagnosis and Treatment
- Ocular Surface and Contact Lens
- Allergic Rhinitis and Sensitization
- Lung Cancer Diagnosis and Treatment
- Cancer Diagnosis and Treatment
- Trauma Management and Diagnosis
- Olfactory and Sensory Function Studies
- Neuroinflammation and Neurodegeneration Mechanisms
- Glaucoma and retinal disorders
- Surgical site infection prevention
- Cleft Lip and Palate Research
- Occupational exposure and asthma
- Cancer and Skin Lesions
- COVID-19 and healthcare impacts
- Cancer Immunotherapy and Biomarkers
- Cystic Fibrosis Research Advances
- CNS Lymphoma Diagnosis and Treatment
- Traumatic Brain Injury and Neurovascular Disturbances
Humanitas University
2022-2025
IRCCS Humanitas Research Hospital
2022-2025
Casa di Cura Columbus
2024
Objective The reboot approach could be an effective treatment option to lower recurrence rates (RRs) in recalcitrant Chronic Rhinosinusitis with Nasal Polyps (CRSwNP). purpose of this study was investigate RR, recurrence‐free survival (RFS), quality life (QoL) improvement, and oral corticosteroid (OCS) intake pluri‐operated CRSwNP patients treated partial surgery. Methods A consecutive sample CRSwNP, ineligible for monoclonal antibodies, underwent 22‐item SinoNasal Outcome Test (SNOT‐22),...
In the last 20 years, growing interest in chronic rhinosinusitis (CRS) has become evident medical literature; nevertheless, it is still difficult to identify real prevalence of disease. Epidemiological studies are few and focused on heterogeneous populations diagnostic methods. Recent research contributed identifying CRS as a disease characterized by clinical scenarios, high impact quality life, elevated social costs. Patient stratification with phenotypes identification pathobiological...
Abstract Purpose Few evidence-based therapies are available for chronic olfactory dysfunction after COVID-19. This study investigated the relative efficacy of training alone, co-ultramicronized palmitoylethanolamide with luteolin (um-PEA–LUT, an anti-neuroinflammatory supplement) or combined therapy treating from Methods double-blinded controlled, placebo-controlled multicenter randomized clinical trial was conducted in 202 patients persistent COVID-19 > 6 month duration. After a...
Objective To provide real‐life evidence on long‐term radiological changes in patients with severe chronic rhinosinusitis nasal polyps (CRSwNP) treated dupilumab, and to assess possible differences between clinical results terms of endoscopic findings Patient‐Reported‐Outcomes (PROs). Methods Consecutive dupilumab for recalcitrant CRSwNP were required undergo CT scan at baseline (T0) after 12 (T1) since first administration. A group also performed 52 weeks (T2) outcomes. At each timepoint,...
ABSTRACT Objective This study aims to determine whether preoperative supplementation of vitamin D reduces the incidence hypocalcemia following total thyroidectomy. Methods Conducted in conformity with PRISMA statement, a systematic review and meta‐analysis randomized clinical trials (RCT) was performed assessing postoperative symptomatic hypocalcemia. Results The search strategy yielded 3808 potentially relevant publications, eight RCTs ultimately included. These included 902 patients...
Purpose: Although the effectiveness of molecular antibodies has been established, evidence is still lacking on objective predictors response. The aim this study was to assess whether extent previous endoscopic sinus surgeries, assessed by means Amsterdam Classification Completeness Endoscopic Sinus Surgery (ACCESS) score, may influence clinical outcomes in refractory CRSwNP patients treated with dupilumab. Materials and Methods: A consecutive sample dupilumab for previously operated...
Background: Anti-glaucoma eye drops have been investigated due to their production of fibrotic changes on the conjunctival surface, undermining functioning upper lacrimal drainage system. We aimed assess whether these effects may impair effectiveness endoscopic endonasal dacryocystorhinostomy (EE-DCR). Methods: This is a single-center observational retrospective study EE-DCR via posterior approach. Resolution epiphora and dacryocystitis were analyzed after 1 (T1) 6-months (T2) from surgery....
Chronic rhinosinusitis (CRS) and nasal septum deviation (SD) are two widely diffused clinical conditions in otorhinolaryngology practice. Albeit symptoms the most commonly referred by patients affected both conditions, recent evidence has explored impairment of function beyond its local implication. Indeed, prevalence psychiatric disorders, specifically anxiety depression, was found higher suffering from SD or CRS than general population. The aim this study to evaluate burden these terms...
Evaluation of effectiveness non-mucosa-sparing (eg, reboot) surgery in patients with chronic rhinosinusitis nasal polyps (CRSwNP), poorly responders to mAb therapy, who failed repeated comprehensive endoscopic surgeries.
To elaborate a preoperative score to predict the necessity of enteral nutrition at 28 days postoperatively in patients undergoing head and neck surgery.A total 424 with oral cavity, oropharyngeal, laryngeal, hypopharyngeal carcinoma were retrospectively enrolled analyzed identify predictors prolonged postsurgical feeding which used create prediction model an easy-to-use nomogram.Five variables (body mass index, previous radiotherapy, dysphagia, type surgery, flap reconstruction) found be...