A5087218596- Clinical Nutrition and Gastroenterology
- Infant Nutrition and Health
- Central Venous Catheters and Hemodialysis
- Intestinal Malrotation and Obstruction Disorders
- Pediatric Hepatobiliary Diseases and Treatments
- Child Nutrition and Feeding Issues
- Abdominal Surgery and Complications
- Esophageal and GI Pathology
- Neonatal Respiratory Health Research
- Congenital gastrointestinal and neural anomalies
- Thyroid and Parathyroid Surgery
- Dialysis and Renal Disease Management
- Thyroid Cancer Diagnosis and Treatment
- Nutrition and Health in Aging
- Congenital Anomalies and Fetal Surgery
- Nosocomial Infections in ICU
- Hernia repair and management
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Ovarian cancer diagnosis and treatment
- Appendicitis Diagnosis and Management
- Diet and metabolism studies
- Electrolyte and hormonal disorders
- Gut microbiota and health
- Intestinal and Peritoneal Adhesions
- Intraperitoneal and Appendiceal Malignancies
University of British Columbia
2005-2025
British Columbia Children's Hospital
2018-2025
The University of Queensland
2022
B.C. Women's Hospital & Health Centre
2021
The University of Texas Southwestern Medical Center
2011-2018
Children's Medical Center
2011-2016
Hospital for Sick Children
2012-2013
SickKids Foundation
2013
Pediatric Oncology Group
2012
Harvard University
2006-2011
OBJECTIVES. Given the demonstrated benefit of euglycemia in critically ill patients as well risk for hypoglycemia during insulin infusion children, we sought to validate a subcutaneous sensor real-time continuous glucose monitoring pediatric and after cardiac surgery. METHODS. Children up 36 months age who were undergoing bypass surgery recruited. After anesthetic induction, glucose-monitoring system (CGMS, Medtronic Minimed, Northridge, CA) was inserted subcutaneously. Sensors remained...
Background: Children with short bowel syndrome (SBS) can vary significantly in their growth trajectory. Recent data have shown that children SBS possess a unique gut microbiota signature compared healthy controls. We hypothesized and poor would exhibit more severe dysbiosis those who are growing adequately, despite similar intestinal anatomy. Materials Methods: Stool samples were collected from (n = 8) controls 3) over 3 months. Gut populations (16S ribosomal RNA sequencing metagenomic...
Abstract Background Intestinal failure (IF) is a life‐limiting condition that includes variety of intestinal pathologies. Currently, there are few clinical biomarkers reflect function or patient's potential to wean off parenteral nutrition (PN), making it difficult predict the trajectory. By associating gut microbiome taxonomic and functional features blood analytes with proportion daily energy delivered via PN—a proxy for function—our study aimed discover predictors PN weaning potential....
Infants with intestinal failure often require long-term central access for delivery of parenteral nutrition (PN). Traditionally, surgically placed venous catheters (CVCs) have been used; however, the complications associated these can lead to significant morbidity. Peripherally inserted (PICCs) are potentially superior CVCs because they tend be smaller, and without general anesthesia. The purpose study is report use PICCs administration PN in infants compare previously published catheter...
Critically ill neonates on extracorporeal life support (ECLS) demonstrate elevated rates of protein breakdown that, in turn, are associated with increased morbidity and mortality. This study sought to determine if the administration anabolic hormone insulin improved net balance ECLS.Twelve parenterally fed neonates, ECLS, were enrolled a randomized, prospective, crossover trial. Subjects administered hyperinsulinemic euglycemic clamp control saline infusion. Protein metabolism was quantified...
Intestinal neuronal dysplasia type B (IND) denotes an increased proportion of hyperplastic submucosal ganglia, as resolved histochemically in 15-μm-thick frozen sections. IND has been reported proximal to the aganglionic segment patients with Hirschsprung disease (HSCR) and is putatively associated a higher rate postsurgical dysmotility. We developed validated histological criteria diagnose IND-like ganglion cell hyperplasia (IND-SH) paraffin sections used approach study incidence clinical...