A5017955440- Electrospun Nanofibers in Biomedical Applications
- Silk-based biomaterials and applications
- Textile materials and evaluations
- Advanced Sensor and Energy Harvesting Materials
- Advanced Materials and Mechanics
- Material Properties and Processing
- Periodontal Regeneration and Treatments
- biodegradable polymer synthesis and properties
- Modular Robots and Swarm Intelligence
- Cellular and Composite Structures
- Bone Tissue Engineering Materials
Swiss Federal Laboratories for Materials Science and Technology
2018-2021
ETH Zurich
2018-2021
The development and application of nanofibres requires a thorough understanding the mechanical properties on single fibre level including respective modelling tools for precise analysis. This work presents morphological study poly-l-lactide developed by needleless electrospinning. Atomic force microscopy (AFM) micromechanical testing (MMT) were used to characterise response fibres within diameter range 200-1400 nm. Young's moduli E determined means both methods are in sound agreement show...
Auxetic materials have gained increasing interest in the last decades, fostered by auspicious applications various fields. While design of new auxetics has largely focused on meta-materials with deterministic, periodically arranged structures, we show here theoretical and numerical analysis that pronounced auxetic behaviour negative Poisson's ratios very large magnitude can occur random fibre networks slender, reasonably straight segments buckle deflect. We further demonstrate experiments...
Diseases of periodontal tissues are a considerable clinical problem, connected with inflammatory processes and bone loss. The healing process often requires reconstruction lost in the area. For that purpose, various membranes used to prevent ingrowth epithelium tissue defect enhance regeneration. Currently-used mainly non-resorbable or derived from animal tissues. Thus, there is an urgent need for non-animal-derived bioresorbable tuned resorption rates porosity optimized circulation body...
Controlling the architecture of engineered scaffolds is outmost importance to induce a targeted cell response and ultimately achieve successful tissue regeneration upon implantation. Robust, reliable reproducible methods control scaffold properties at different levels are timely highly important. However, multiscale architectural electrospun membranes very complex, in particular role fiber-to-fiber interactions on mechanical properties, their effect remain largely unexplored. The work...