A5079053571- Viral Infections and Vectors
- Influenza Virus Research Studies
- Vector-Borne Animal Diseases
- Animal Disease Management and Epidemiology
- Respiratory viral infections research
- Monoclonal and Polyclonal Antibodies Research
- Mosquito-borne diseases and control
- Animal Virus Infections Studies
- Plant Virus Research Studies
- Viral gastroenteritis research and epidemiology
- Virus-based gene therapy research
- RNA and protein synthesis mechanisms
- SARS-CoV-2 and COVID-19 Research
- interferon and immune responses
- Fire effects on ecosystems
- Virology and Viral Diseases
- COVID-19 epidemiological studies
- Agricultural pest management studies
- Immune Response and Inflammation
- Ferrocene Chemistry and Applications
- Diabetes and associated disorders
- Hepatitis Viruses Studies and Epidemiology
- Vector-borne infectious diseases
- Glycosylation and Glycoproteins Research
- Yersinia bacterium, plague, ectoparasites research
Ministry of Health of the Russian Federation
2015-2022
D.I. Ivanovsky Institute of Virology Russian Academy of Medical Sciences
1989-2021
Institute of Virology of the Slovak Academy of Sciences
2019
Gamalei Institute of Epidemiology and Microbiology
2017
Ministry of Health
2014-2015
Development Agency of Serbia
2014
Russian Academy of Sciences
1965
We found and genetically described two novel SARS-like coronaviruses in feces oral swabs of the greater (R. ferrumequinum) lesser hipposideros) horseshoe bats southern regions Russia. The viruses, named Khosta-1 Khosta-2, together with related viruses from Bulgaria Kenya, form a separate phylogenetic lineage. evidence recombination events evolutionary history Khosta-1, which involved acquisition structural proteins S, E, M, as well nonstructural genes ORF3, ORF6, ORF7a, ORF7b, virus that is...
To elucidate the structure of antigenic sites avian H5 influenza virus haemagglutinin (HA) we analysed escape mutants a mouse-adapted variant H5N2 strain A/Mallard/Pennsylvania/10218/84. A panel five anti-H5 monoclonal antibodies (mAbs) was used to select 16 mutants. The were tested by ELISA and haemagglutination inhibition with this mAbs HA genes sequenced. sequencing demonstrated that amino acid changes grouped in two sites. One corresponded site H3 HA. other contained areas are separated...
The family Bunyaviridae has more than 530 members that are distributed among five genera or remain to be classified. genus Orthobunyavirus is the most diverse bunyaviral with 220 viruses have been assigned 18 serogroups based on serological cross-reactions and limited molecular-biological characterization. Sequence information for all three orthobunyaviral genome segments only available belonging Bunyamwera, Bwamba/Pongola, California encephalitis, Gamboa, Group C, Mapputta, Nyando, Simbu...
Variants of influenza A/USSR/90/77 (H1N1) virus selected with monoclonal antibody HC 142 (Res 142-1 and Res 142-2) were resistant to this in a virus-neutralization (VN) test, but inhibited haemagglutination-inhibition (HI) test. A variant 22 22) was only VN tests. mouse-adapted A/USSR/90/77, shown previously be 22, reacted manner similar that 142-1, 142-2 22. Another antibody, 125, behaved similarly 142. The addition anti-immunoglobulin serum restored the ability 125 (already bound virus)...
ABSTRACT The bunyaviral monogeneric family Nairoviridae currently includes 12 species for 35 distinct viruses. Here, we present the complete genome coding sequences of an additional seven nairoviruses. Five them can be assigned to established species, whereas two (Artashat and Chim viruses) ought novel species.
Abstract Influenza virus nucleoprotein (NP) binds to the viral genome RNA and forms internal ribonucleoprotein complex of particle. Avian human influenza NP have characteristic differences at several amino acid positions. It is not known whether any these can be recognized by antibodies. In present study five monoclonal antibodies (MAbs) were produced against A/Duck/Novosibirsk/56/05 (H5N1) virus. Two MAbs discerned avian strains on ELISA testing. The expressed in a prokaryotic system was...