A5023663018- Influenza Virus Research Studies
- Coronary Interventions and Diagnostics
- Respiratory viral infections research
- Cardiac Imaging and Diagnostics
- Acute Myocardial Infarction Research
- Cardiac Valve Diseases and Treatments
- Cardiac and Coronary Surgery Techniques
- RNA and protein synthesis mechanisms
- Cerebrovascular and Carotid Artery Diseases
- Aortic Disease and Treatment Approaches
- Animal Disease Management and Epidemiology
- Infective Endocarditis Diagnosis and Management
- Peripheral Artery Disease Management
- Protein Structure and Dynamics
- Spacecraft Dynamics and Control
- Viral gastroenteritis research and epidemiology
- Space Satellite Systems and Control
- Venous Thromboembolism Diagnosis and Management
- Bacteriophages and microbial interactions
- Viral Infections and Immunology Research
- Aerospace Engineering and Control Systems
- Viral Infections and Vectors
- Acute Ischemic Stroke Management
- Antiplatelet Therapy and Cardiovascular Diseases
- Mechanical Circulatory Support Devices
Kemerovo State University
2016-2023
Ministry of Health of the Russian Federation
2015-2023
Research Institute of Complex Problems of Cardiovascular Disease Russian Academy of Medical Sciences
2017-2023
St. Petersburg Institute for Informatics and Automation
2022
National Research Mordovia State University
2021
Bauman Moscow State Technical University
2021
Moscow Power Engineering Institute
2021
Moscow Aviation Institute
2021
Kemerovo Cardiology Center
2019-2020
Institute of Virology of the Slovak Academy of Sciences
2019
We mapped the hemagglutinin (HA) antigenic epitopes of a highly pathogenic H5N1 influenza virus on three-dimensional HA structure by characterizing escape mutants recombinant containing A/Vietnam/1203/04 (H5N1) deltaHA and neuraminidase genes in genetic background A/Puerto Rico/8/34 (H1N1) virus. The were selected with panel eight anti-HA monoclonal antibodies (MAbs), seven to one A/Chicken/Pennsylvania/8125/83 (H5N2) virus, mutants' sequenced. amino acid changes suggested three MAb groups:...
Aim . Optimal revascularization strategy in multivessel (MV) coronary artery disease (CAD) eligible for percutaneous management (PCI) and surgery remains unresolved. We evaluated, a randomized clinical trial, residual myocardial ischemia (RI) outcomes of MV-CAD using bypass grafting (CABG), hybrid (HCR), or MV-PCI. Methods Consecutive patients ( n = 155) were (1 : 1 1) to conventional CABG (LIMA-LAD plus venous grafts) HCR (MIDCAB LIMA-LAD followed by PCI remaining vessels) MV-PCI...
The highly pathogenic avian influenza H5N1 viruses have become widespread and evolved into several clades. In our previous studies, the antigenic sites of H5 hemagglutinin (HA) were characterized by selection sequencing escape mutants. present studies we analyzed epitopes recognized monoclonal antibodies against A/Duck/Novosibirsk/56/05 (H5N1) virus isolated in western Siberia belonging to subclade 2.2 viruses. analysis revealed antigenically relevant positions amino acid residues globular...
Studying the role of soluble ST2 (sST2) during hospitalization for myocardial infarction (MI) can be helpful predicting course and development complications.We included 88 patients with MI (median age, 58 yr). Depending on hospitalization, were divided into two groups: favorable (n=58) unfavorable (n=30) outcome groups. On days 1 12 after MI, serum sST2 N-terminal pro-brain natriuretic peptide (NT-proBNP) measured by ELISA.On day 1, concentrations NT-proBNP increased 2.4- 4.5-fold, compared...
Aim To evaluate 5-year results of the HREVS (Hybrid REvascularization Versus Standarts) study.Material and methods The study included 155 consecutive patients with multivessel coronary artery disease who were randomized into 3 groups: bypass grafting (CABG) (n=50), hybrid revascularization (HCR) (n=52) percutaneous intervention (PCI) (n=53) according to consensus cardiology team on technical clinical feasibility each three strategies. primary endpoint was residual ischemia 12 months after...
SUMMARY The influenza virus H1N1 (the A/USSR/90/77 strain) that reappeared in 1977 after the viruses had disappeared from human population, is compared with A/FM/1/47 and A/FW/1/50 by method of oligonucleotide mapping individual segments viral RNAs. Seven genes appear to be very similar corresponding virus, whereas gene coding for M protein displays considerable homology virus. data demonstrate strain a recombinant
Currently, transcatheter aortic valve implantation (TAVI) represents the most efficient treatment option for patients with stenosis, yet its clinical outcomes largely depend on accuracy of positioning that is frequently complicated when routine imaging modalities are applied. Therefore, existing limitations perioperative underscore need development novel visual assistance systems enabling accurate procedures. In this paper, we propose an original multi-task learning-based algorithm tracking...
Background: Cardiovascular diseases and type 2 diabetes mellitus (T2DM) may have common developmental mechanisms associated with lipid metabolism disorders. Dyslipidemia progression of atherosclerosis in people T2DM are accompanied by an increase cardiovascular mortality. This study examined the dose-dependent action atorvastatin on carbohydrate adipokine status patients within 12 months after myocardial infarction (MI). Methods: A total 156 male MI who had received 20 mg/day (78 patients)...
This article provides an overview of the literature on issue minimally invasive hybrid revascularization in patients with stable multivessel coronary artery disease. It is announced design randomized study HREVS (Hybrid REvascularization Vs Surgery), to compare results myocardial using three strategies: 1) pump bypass surgery LIMA LAD (MID CAB) and stenting other arteries drug-eluting stents); 2) grafting cardiopulmonary bypass; 3) stents.
Mutations arising in influenza viruses that have undergone immune pressure may promote a successful spread of mutants nature.In order to evaluate the variability nonpathogenic virus A/duck/Moscow/4182-C/2010(H5N3) and determine common epitopes between it highly pathogenic H5N1 avian (HPAIV), set escape was selected due action MABs specific against A/chicken/Pennsylvania/8125/83(H5N2), A/Vietnam/1203/04(H5N1) A/duck/ Novosibirsk/56/05(H5N1) viruses.The complete genomes were sequenced amino...
Aim: To assess growth stimulating factor ST2 and N-terminal pro b-type natriuretic peptide (NT-proBNP) levels in the sera of myocardial infraction (MI) patients, their correlation with adaptive maladaptive variants cardiac remodelling.Methods: 87 patients (65 male, 22 females; 67±8.36 years) ST-elevated MI were included this study, 67 had an adaptive, physiological, while 20 a maladaptive, pathological variant myocardium remodelling.Results: On day 1, NT-proBNP shown to increase 2.4 4.5...