Maritza G. Verdugo-Molinares

ORCID: 0000-0002-8413-0229
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About
Contact & Profiles
Research Areas
  • Extracellular vesicles in disease
  • Eicosanoids and Hypertension Pharmacology
  • Metabolomics and Mass Spectrometry Studies
  • Drug Transport and Resistance Mechanisms
  • Machine Learning and ELM
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Chronic Kidney Disease and Diabetes
  • Biopolymer Synthesis and Applications
  • Gestational Diabetes Research and Management
  • Birth, Development, and Health
  • biodegradable polymer synthesis and properties
  • COVID-19 Clinical Research Studies
  • Acute Kidney Injury Research
  • Lipid metabolism and biosynthesis
  • Genetics, Bioinformatics, and Biomedical Research
  • Pregnancy and preeclampsia studies
  • MicroRNA in disease regulation
  • Long-Term Effects of COVID-19
  • Advanced Proteomics Techniques and Applications
  • Microencapsulation and Drying Processes
  • Cardiac Ischemia and Reperfusion
  • Cholesterol and Lipid Metabolism
  • Organ Transplantation Techniques and Outcomes

Mexican Social Security Institute
2023-2024

Secretaría de Salud de Jalisco
2022-2024

Centro de Investigación y Asistencia en Tecnología y Diseño del Estado de Jalisco
2022-2024

Consejo Nacional de Humanidades, Ciencias y Tecnologías
2023

The targeting of transforming growth factor β (TGF-β) has been shown to reduce complications related ischemia-reperfusion injury (IRI) post-surgically. Pirfenidone (PFD) specifically inhibits TGF-β expression and demonstrated provide protection from IRI in short-term allograft models, though not yet long-term models. A chronic unilateral model was established using male Wistar rats. animals were divided into two groups: one with a pre-treatment PFD (0.5 mg/kg) followed by 0.5 mg/kg/day...

10.3390/ddc2010009 article EN cc-by Drugs and Drug Candidates 2023-03-13

Renal ischemia reperfusion (IR) presents a common challenge for organ graft and function after transplantation. In the kidney, although there are several mechanisms involved in IR injury, some studies have pointed to angiogenesis as an important process pathophysiology of and, therefore, possible target mechanism reduce damage. Angiogenesis can be modulated by different molecules recent evidence has shown that opioids among these molecules. preconditioning with is useful non-invasive...

10.3390/ddc2010001 article EN cc-by Drugs and Drug Candidates 2023-01-07
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