A5059004264- Cancer, Hypoxia, and Metabolism
- Metabolism, Diabetes, and Cancer
- Diet, Metabolism, and Disease
- Amino Acid Enzymes and Metabolism
- Obstructive Sleep Apnea Research
- Arsenic contamination and mitigation
- Advanced Sensor and Energy Harvesting Materials
- Phagocytosis and Immune Regulation
- Electrospun Nanofibers in Biomedical Applications
- Cancer Research and Treatments
- Nanoparticles: synthesis and applications
- Immunotoxicology and immune responses
- Cancer Cells and Metastasis
- Salivary Gland Disorders and Functions
- TGF-β signaling in diseases
- Tissue Engineering and Regenerative Medicine
- Biochemical Analysis and Sensing Techniques
- Mesenchymal stem cell research
- Cancer, Lipids, and Metabolism
- Mass Spectrometry Techniques and Applications
CryoLife (United States)
2024
Michigan Technological University
2017-2022
Houghton University
2018-2019
The specificity of carbohydrate transporters towards their substrates poses a significant challenge for the development molecular probes to monitor sugar uptake in cells biochemical and biomedical applications. Herein we report new set coumarin-based fluorescent conjugates applicable analysis fructose due free passage through fructose-specific transporter GLUT5. reported cover broad range fluorescence spectrum providing essential tools evaluation transport capacity live cells.
Point-of-care applications rely on biomedical sensors to enable rapid detection with high sensitivity and selectivity. Despite advances in sensor development, there are challenges cancer diagnostics. Detection of biomarkers, cell receptors, circulating tumor cells, gene identification, fluorescent tagging time-consuming due the sample preparation response time involved. Here, we present a novel approach target enhanced metabolism breast cancers for using imaging. Fluorescent analogs fructose...
In tissue engineering, the use of scaffolds helps establish a synergistic relationship between and tissues by improving cell-scaffold interaction. This interaction is enhanced when physiologically relevant biophysical cues are replicated in artificial scaffolds. Here, we present novel scaffold that mimics natural anisotropy native extracellular matrix tissues, fabricated electrospinning combination three polymers: polycaprolactone (PCL), polyvinylidene fluoride (PVDF) polyaniline (PANI). The...
Arsenic (As) is one of the most toxic environmental pollutants, classified as a Class I carcinogen. Anthropogenic activities have led to an increase in As contamination soils. Using animal models study health impacts time and cost-prohibitive, hence attempts been made develop in-vitro cell culture models. However, studies so far not represented realistic exposure conditions. We exposed Human Immortalized Keratinocyte (HaCaT) Primary Dermal Fibroblasts (HDFa) cells water-soluble fraction...
Review on TGFBR2, with data DNA/RNA, the protein encoded and where gene is implicated.
Oropharyngeal fat volume is associated with obstructive sleep apnea (OSA) severity. Selective adipose cryolysis may produce cold-induced cell death while sparing surrounding tissues. This study explored (1) similarities in tongue between porcine and human models (2) the feasibility potential reduction of lingual using selective cryolysis.
Rapid detection of carcinogenesis is the holy grail in timely cancer and point-of-care applications. Realization these applications has been hampered by lack specificity and/or selectivity biomarkers low concentrations at which are available. A majority technologies rely on cell-receptor interactions, activation specific receptors, gene identification fluorescent tagging. All techniques time consuming often require specialized equipment. Here we present a method to use enhanced metabolism...
Abstract Background: Current cancer imaging agents are limited in their ability to distinguish cancers from normal cells (low cancer-selectivity) and identify at different stages of development cancer-specificity). This limitation makes biopsy mandatory for diagnosis continuous treatment monitoring. Analysis samples may also have some ambiguity clearly identifying malignant metastatic cells, resulting cases mischaracterization overdiagnosis. Hence, cancer-selective cancer-specific needed....