A5041601097- Genetic factors in colorectal cancer
- BRCA gene mutations in cancer
- Cancer Genomics and Diagnostics
- Medical and Biological Sciences
- Nutrition, Genetics, and Disease
- Bladder and Urothelial Cancer Treatments
- Lung Cancer Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Circular RNAs in diseases
- Colorectal Cancer Treatments and Studies
- Metastasis and carcinoma case studies
- Hepatitis C virus research
- Reconstructive Surgery and Microvascular Techniques
- Cancer-related molecular mechanisms research
- Cancer Risks and Factors
- Hepatocellular Carcinoma Treatment and Prognosis
- Peroxisome Proliferator-Activated Receptors
- Multiple and Secondary Primary Cancers
- Cancer Immunotherapy and Biomarkers
- Lung Cancer Treatments and Mutations
- Adipose Tissue and Metabolism
- Education, Innovation and Language Studies
- Cancer, Hypoxia, and Metabolism
- Wound Healing and Treatments
- linguistics and terminology studies
City Hospital
2025
City Clinical Hospital
2024-2025
Moscow City Oncology Hospital №62
2020-2023
Ural State Medical University
2016-2019
Chelyabinsk State Medical Academy
2016
Background : Routine analysis of KRAS, NRAS, BRAF V600 mutations, as well MSI and HER2 guides treatment selection in colorectal cancer (CRC). Recent findings from the PRESSING PARADIGM trials have demonstrated that negative hyperselection patients based on results comprehensive genomic profiling better outcomes following anti-EGFR therapy. Study objective: The study aimed to retrospectively analyze occurrence alterations associated with potential resistance samples CRC treated Materials...
Background. Genomic alterations in urothelial carcinoma (UC) cells range from point DNA mutations to complex chromosomal rearrangements and changes the number of chromosomes tumor cell. The UC genetic profile is highly heterogeneous, leading significant variability natural history disease, prognosis, responses treatment. To evaluate Russian patients with bladder cancer great interest. Aim. mutation specimens next-generation sequencing (NGS) panel for 523 genes. Materials methods. Thirty-six...
Russia and other countries report an increase in the incidence of malignant neoplasms, approximately 10 % all oncological cases have hereditary background. Molecular genetic testing patients with diagnosed neoplasms a suspected factor will help to select effective modern methods treatment prevention development localizations.
 According study, 12,6 had cancer syndrome, which allowed administer molecular tests patients’ relatives. Consequently, it becomes possible detect risk factors,...
Background. Malignant tumors of the thyroid gland represent a significant problem in oncology due to high prevalence and difficulty diagnosis at outpatient stage, requiring efforts multidisciplinary team – oncologist, cytologist, ultrasound diagnostics specialist. Purpose study. To improve cancer by reducing examination time increasing informativeness cytological with multimodal approach. Material methods. We analyzed routing system for patients suspected Federal Budgetary Healthcare...
6—7 февраля 2015 г. в Челябинске состоялась Всероссийская научно-практическая патологоанатомическая конференция с международным участием «Современные подходы к морфологической диагностике новообразований человека», посвященная 70-летию Челябинского областного клинического онкологического диспансера. Организаторами конференции являлись Министерство здравоохранения Челябинской области, Российское общество патологоанатомов (РОП), ГБОУ ВПО «ЮжноУральский государственный медицинский университет»...
Describe the structure of pathogenic germline variants and clinical anatomical features in colorectal cancer patients Moscow.The whole genome sequencing results with suspected hereditary syndrome were evaluated. All identified genetic validated using Sanger sequencing.The study included 238 cancer, 41/238 (17.2%) have associated syndromes or increased risk. Lynch accounts for 8% all cases (19/238), familial adenomatous polyposis - 1.7% (4/238). 5 new described first time a Russian patients:...
Introduction. Genetic testing has become the part of practice providing specialized cancer care. This allows not only detecting further tactics for patient management, but also identifying a risk group occurrence malignant neoplasms (MNP). However, there are still no algorithms dispensary monitoring healthy carriers mutations, which determined relevance our study.
 The purpose study was to propose an organizational model work office hereditary tumor pathology (HTP) based on analysis own...
Lung cancer is one of the main causes death. It a heterogeneous group malignant neoplasms, treatment tactics for which directly depends on tumor morphology and genetic characteristics. However, pathomorphological differential diagnosis adenocarcinoma squamous cell lung difficult in some cases an immunohistochemical (IHC) study needed to verify these tumors; moreover, IHC panel should include both pneumocyte markers. Fifty surgical biopsy specimens underwent morphological studies using...
Early diagnosis is crucial for an effective cancer management. Cancers of the head and neck, ENT organs in particular, are among top ten most common human malignancies. The upper respiratory tract affected by squamous cell carcinomas, lymphomas, adenoid cystic carcinomas. Nasopharyngeal neoplasms characterized mild non-specific manifestations, especially at initial stages development. Mild symptoms localization peculiarities result delayed these tumors. Lymphomas localized pharynx can cause...