A5044873313- Diabetic Foot Ulcer Assessment and Management
- Wound Healing and Treatments
- European and International Law Studies
- Peripheral Artery Disease Management
- Pressure Ulcer Prevention and Management
- Reconstructive Surgery and Microvascular Techniques
- Privacy, Security, and Data Protection
- Tendon Structure and Treatment
- Surgical site infection prevention
- Surgical Sutures and Adhesives
- Orthopedic Surgery and Rehabilitation
- Education, Healthcare and Sociology Research
- Anesthesia and Pain Management
- Diagnosis and Treatment of Venous Diseases
- Digitalization, Law, and Regulation
- Foot and Ankle Surgery
- European Criminal Justice and Data Protection
- Libraries and Information Services
- Reconstructive Facial Surgery Techniques
- Social and Educational Sciences
- Narrative Theory and Analysis
- Streptococcal Infections and Treatments
- Linguistic research and analysis
- Cerebrovascular and Carotid Artery Diseases
- Dermatologic Treatments and Research
Yale New Haven Hospital
2003-2025
Yale University
2012-2023
Technische Universität Ilmenau
2022
Stony Brook University
2015
University of Connecticut
2015
American College of Foot and Ankle Surgeons
2010
Heritage Preservation
2007-2009
Matrix Research (United States)
2008
Quinnipiac University
2007
Georgetown University
1997-2006
OBJECTIVE—The purpose of this study was to evaluate safety and clinical efficacy negative pressure wound therapy (NPWT) compared with advanced moist (AMWT) treat foot ulcers in diabetic patients. RESEARCH DESIGN AND METHODS—This multicenter randomized controlled trial enrolled 342 patients a mean age 58 years; 79% were male. Complete ulcer closure defined as skin (100% reepithelization) without drainage or dressing requirements. Patients randomly assigned either NPWT (vacuum-assisted...
This retrospective study compared the clinical outcomes of negative pressure wound therapy with reticulated open cell foam (NPWT/ROCF) as delivered by Vacuum‐Assisted Therapy ® (V.A.C. Therapy, KCI Licensing Inc., San Antonio, TX) to non‐NPWT/ROCF conventional (CT) in split‐thickness skin graft (STSG) survival all patients determine whether NPWT/ROCF affects outcome survival, terms overall take, duration repeated grafts and complications. The authors conducted a 10‐year review 142 admitted...
ABSTRACT We assessed the safety and efficacy of Formulated Collagen Gel (FCG) alone with Ad5PDGF‐B (GAM501) compared Standard Care (SOC) in patients 1.5–10.0 cm 2 chronic diabetic neuropathic foot ulcers that healed <30% during Run‐in. Wound size was by planimetry acetate tracings photographs 124 patients. Comparison data sets revealed frequently overestimated areas at some sites. For per‐protocol analysis, 113 qualified using but only 82 photographs. Prior animal studies suggested...
We present a case report of revision talonavicular joint arthrodesis following painful nonunion. Following the removal previously united subtalar hardware, posterior screw tunnel was used to access internal aspect calcaneus for bone and marrow harvesting avoiding second graft site incision. A suction curettage system then acquire adequate autologous cancellous nondiluted marrow. The prepared arthrodesis, followed by augmentation with rigid fixation placed across compression. There were no...
We conducted a post-hoc retrospective analysis of patients enrolled in randomized controlled trial to evaluate overall costs negative pressure wound therapy (NPWT; V.A.C. Therapy; KCI USA, Inc, San Antonio, Texas) versus advanced moist (AMWT) treating grade 2 and 3 diabetic foot wounds during 12-week course.Data from two study arms (NPWT [n = 169] or AMWT 166]) originating Protocol VAC2001-08 were collected patient records used as the basis calculations performed our cost analysis.A total...
The diagnosis of pedal osteomyelitis is onen complicated by the presence pre-existing bony abnormalities. In this study, utility radiolabeled white blood cell imaging for detection was evaluated. Twenty-seven men and women were prospectively enrolled underwent plain film radiography, three-phase bone scan, Tc-99m hexamethylpro-pylamine oxine scintigraphy their feet. or absence confirmed in all subjects microbiologic histopathologic analysis resected tissue. results indicated that more...
We appreciate Dr. Hemkens and Waltering's (1) comments on our recently published article the use of negative pressure wound therapy (NPWT) as delivered by vacuum-assisted closure in treatment diabetic foot ulcers (2). We thank Waltering for recognizing difficulty conducting this randomized clinical trial a blinded fashion. However, we did insure that selection was conducted Neither physician nor patient aware assignment before enrolling. Hemkins also state there high proportion censored...
A retrospective study was undertaken to evaluate a singlestage approach in the treatment of noninfected, chronic, well-perfused diabetic foot wounds. This single-stage consisted total excision ulcer with broad exposure, correction underlying osseous deformity, and immediate primary closure using local random flap. Four hundred cases pedal ulcers were analyzed by chart review. Of those, 67 underwent surgical for length hospital stay, postoperative complications, time heal, recurrence ulcer,...
This retrospective study reviewed 80 consecutive patients (mean age 62 years; range 21-91 years) who underwent 91 transmetatarsal amputations (TMAs) between 1995 and 2003. The mean follow-up was 12 +/- 1.36 months. Sixty-two TMAs healed initially (group 1), whereas 29 did not heal by 3 months 2). At the final examination, in groups 1 2, 63 of (69%) limbs were healed. Of 28 that heal, 25 (89%) required further proximal amputation. Initial healing correlated significantly with ability to...
ABSTRACT The aim of this study is to compare the effect a high‐frequency repetitive (HF) stretch or an intermittent (I) on cell proliferation and survival human dermal fibroblasts determine activation any relevant signal pathways. Cultured were exposed either HF I stretch. Cell number was measured by counting, while DNA synthesis assessed 5‐bromo‐2′‐deoxyuridine (BrdU) staining apoptosis terminal deoxynucleotidyl transferase‐mediated dUTP nick‐end labeling staining. To investigate potential...
The authors review the impact, areas of influence, and treatment protocols for diabetic foot disease.