Ganapathy Saravanan

ORCID: 0000-0002-8482-0836
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About
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Research Areas
  • Natural Antidiabetic Agents Studies
  • Diet, Metabolism, and Disease
  • Garlic and Onion Studies
  • Adipose Tissue and Metabolism
  • Medicinal Plants and Neuroprotection
  • Pharmacological Effects of Natural Compounds
  • Adipokines, Inflammation, and Metabolic Diseases
  • Invertebrate Taxonomy and Ecology
  • Regulation of Appetite and Obesity
  • Ginger and Zingiberaceae research
  • Liver Disease Diagnosis and Treatment
  • Chemotherapy-induced organ toxicity mitigation
  • Natural product bioactivities and synthesis
  • Educational Games and Gamification
  • Phytochemicals and Antioxidant Activities
  • Advanced Glycation End Products research
  • Pancreatic function and diabetes
  • Piperaceae Chemical and Biological Studies
  • Fatty Acid Research and Health
  • Herbal Medicine Research Studies
  • Biochemical Analysis and Sensing Techniques
  • Advances in Cucurbitaceae Research
  • Phytochemicals and Medicinal Plants
  • Traditional Chinese Medicine Analysis
  • Growth Hormone and Insulin-like Growth Factors

ASA College
2018-2024

KS Rangasamy College of Arts and Science
2015-2024

Amrita Vishwa Vidyapeetham
2022

French Institute of Pondicherry
2012-2022

Karpagam Academy of Higher Education
2015

Bharathiar University
2009-2011

Dr. Reddy's Laboratories (United States)
2007

Dr. Reddy's Laboratories (India)
2007

Bharathidasan University
2004

Obesity represents a rapidly growing threat to the health of populations and diet intervention has been proposed as one strategies for weight loss. Ginger its constituents have used their anti-flatulent, expectorant appetising properties they are reported possess gastro-protective cholesterol-lowering properties. The present study investigated effects gingerol on changes in body weight, serum glucose, insulin, insulin resistance lipid profile plasma liver well activity amylase, lipase leptin...

10.1002/jsfa.6642 article EN Journal of the Science of Food and Agriculture 2014-03-10

Diabetes is often connected with significant morbidity, mortality and also has a pivotal role in the development of cardiovascular diseases. Diet intervention, particularly naturaceutical antioxidants have anti-diabetic potential avert oxidative damage linked diabetic pathogenesis. The present study investigated effects diosgenin, saponin from fenugreek, on changes lipid profile plasma, liver, heart brain high-fat diet-streptozotocin (HFD-STZ)-induced rats. Diosgenin was administered to...

10.1002/jsfa.7057 article EN Journal of the Science of Food and Agriculture 2014-12-22

Black pepper or Piper nigrum is a well-known spice, rich in variety of bioactive compounds, and widely used many cuisines across the world. In Indian traditional systems medicine, it to treat gastric respiratory ailments. The purpose this investigation study antihyperlipidemic antiobesity effects piperonal high-fat diet (HFD)-induced obese rats.Piperonal, an active constituent seeds, was isolated confirmed by HPLC, 1H 13C NMR spectroscopy. Male SD rats were fed on HFD for 22 weeks; Piperonal...

10.1186/s12986-017-0228-9 article EN cc-by Nutrition & Metabolism 2017-11-16

In the present study, we evaluated effect of biochanin A (BCA) on high-fat diet (HFD)-induced obesity cardiomyopathy.BCA (10 mg/kg body weight) was administered to HFD-induced obese rats for 30 days, and its anthropometrical, morphological, plasma cardiac, inflammatory biomarkers, along with cardiac lipid profiles assessed.Supplementation HFD significantly increased mass index, index parameters, profile notable oxidative stress inflammation. Additionally, BCA treatment in demonstrated a...

10.1080/13813455.2021.1874017 article EN Archives of Physiology and Biochemistry 2021-01-20

Combination therapy plays a major part in reducing side effects treatment of breast cancer. For treating HER2-positive cancer, HER2-targeted is common. A natural compound, Plumbagin, gives activity against the HER2 receptor that can be employed cancer therapy. conjugation plumbagin with Trastuzumab increases its targeting specificity to receptor. However, low stability necessitates an encapsulation silver nanoparticles (AgNPs) widen and therapeutic efficacy. This study using...

10.52783/jns.v14.2282 article EN Journal of Neonatal Surgery 2025-03-18

The present study was carried out to investigate the hypoglycaemic effect of S-allyl cysteine (SAC), a garlic component, on some biochemical parameters STZ induced diabetic rats. rats were treated with SAC at two different doses (100 mg/kg b.w. and 150 b.w.) for 45 days. Treatment significantly decreased levels blood glucose, glycosylated hemoglobin, urea, serum uric acid, creatinine, diminished activities pathophysiological enzymes such as aspartate transaminase (AST), alanine (ALT)...

10.32725/jab.2009.017 article EN Journal of Applied Biomedicine 2009-07-31

In the current study, we evaluated effects of Asiatic acid (AA) on lipid metabolic markers in HFD-induced obese Sprague-Dawley rat model. AA (20 mg/kg BW) was administered orally to HFD-fed rats for 42 days. Changes body composition, glucose, insulin resistance (IR) and profiles tissues, plasma pattern gene expression peroxisome proliferator-activated receptor-γ (PPAR-γ) its target genes fatty-acid synthase (FAS), adipocyte protein-2 (aP2) uncoupling (UCP-2) pro-inflammatory factor tumor...

10.1080/13813455.2018.1555668 article EN Archives of Physiology and Biochemistry 2019-02-10

S-allylcysteine, a garlic derivative, could have protective effect against pathogenesis of diabetes mellitus.Sustained free radical generation and oxidative damage to system leads the final conclusion phase also it coexists with constant diminution in antioxidant status.The present study aims evaluate therapeutic effects S-allylcysteine (SAC) adipocytes hormones defense systems plasma erythrocytes treptozotocin (STZ) induced rats.Diabetic rats were administered SAC (150 mg/kg b.w) orally for...

10.5812/ijem.10927 article EN cc-by-nc International Journal of Endocrinology and Metabolism 2013-10-01
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