- Synthesis and biological activity
- Synthesis and Characterization of Heterocyclic Compounds
- Multicomponent Synthesis of Heterocycles
- Natural product bioactivities and synthesis
- Thermodynamic properties of mixtures
- Chemical Thermodynamics and Molecular Structure
- Phase Equilibria and Thermodynamics
- Chemical Synthesis and Reactions
- Synthesis and Biological Evaluation
- Click Chemistry and Applications
- Organophosphorus compounds synthesis
- Phytochemistry and Biological Activities
- Plant Diversity and Evolution
- Andrographolide Research and Applications
- Quinazolinone synthesis and applications
- Synthesis and Reactivity of Sulfur-Containing Compounds
- Chemical and Physical Properties in Aqueous Solutions
- Biological Activity of Diterpenoids and Biflavonoids
- Synthesis of Organic Compounds
- Bioactive natural compounds
- Crystallization and Solubility Studies
- Analytical Chemistry and Chromatography
- Carbohydrate Chemistry and Synthesis
- Chemical Synthesis and Analysis
- Plant and Fungal Species Descriptions
Sri Venkateswara University
2014-2024
Indian Institute of Technology Tirupati
2019
Indian Institute of Chemical Technology
2015
National Institute of Technology Andhra Pradesh
2015
Siddhartha Medical College
2011
University of Hyderabad
2011
Laila Impex (India)
2006-2007
Chaoyang University of Technology
2005
National Cheng Kung University
2004
Centre National de la Recherche Scientifique
2003
An efficient Hantzsch condensation of polyhydroquinoline derivatives was reported via a fourcomponent coupling reaction aldehydes, dimedone, ethyl acetoacetate and ammonium acetate in the presence HClO 4 -SiO 2 under solvent-free conditions.Operational simplicity, use an economically convenient catalyst, high yield, short times are key features this protocol.
A series of 1,2,4-(triazolo[3,4-b][1,3,4]thiadiazol-6-yl)selenopheno[2,3-d]pyrimidines (10a-j) were synthesized with various substituted anilines and benzoic acids. Structures newly compounds established by IR, (1)H &(13)C NMR LC-MS spectral data. The antioxidant activity the was evaluated DPPH, NO H2O2 radical scavenging methods. for their antimicrobial against Gram +ve -ve bacteria antifungal well diffusion method. Compounds 10d, 10h 10i showed promising antioxidant, antibacterial as these...
Novel quinoxaline-hydrazidehydrazone-1,2,3-triazole hybrids were synthesized, characterized and screened for α-glucosidase inhibitory antioxidant activities.
The first bibliography in the area of inference based on conditional specification was published 1977, A second is compiled, and a combined subject index given.
Black pepper or Piper nigrum is a well-known spice, rich in variety of bioactive compounds, and widely used many cuisines across the world. In Indian traditional systems medicine, it to treat gastric respiratory ailments. The purpose this investigation study antihyperlipidemic antiobesity effects piperonal high-fat diet (HFD)-induced obese rats.Piperonal, an active constituent seeds, was isolated confirmed by HPLC, 1H 13C NMR spectroscopy. Male SD rats were fed on HFD for 22 weeks; Piperonal...
Abstract Mutual solubility and tie‐line data are presented for five ternary‐liquid systems containing n ‐propanol, water the esters ‐propyl acetate, ‐butyl amyl ethyl propionate butyrate. Equilibrium distribution system ‐propanol‐water‐ethyl acetate at 20° reported in literature have been plotted comparison on mutual equilibrium diagrams. The all correlated well by methods of Hand Othmer‐Tobias plait points located method Treybal et al. From diagram, it is seen that above systems, ‐propanol...
Abstract Mutual solubility and tie‐line data are presented for four ternary liquid systems containing methanol, water n ‐butyl acetate, pentyl ethyl propionate butyrate as solvents at 30°. For comparison, equilibrium reported in the literature system methanol–water–ethyl acetate 20° have been plotted on saturation isotherm, distribution selectivity diagrams. The all satisfactorily correlated by methods of Hand Othmer–Tobias, plait points located method Treybal, Weber & Daley. systems, it...
Three new 2'-oxygenated flavonoids, (2S)-5,7,2',3',4'-pentamethoxyflavanone (1), 5-hydroxy-7,8,2',5'-tetramethoxyflavone (2), and echioidinin 2'-O-β-d-(6' '-O-acetyl) glucopyranoside (3), together with four known 7-O-methyldihydrowogonin, 7-O-methylwogonin, skullcapflavone I 2'-methyl ether, I, two diterpenoids, andrograpanin 14-deoxy-11,12-didehydroandrographolide, were isolated from the whole plant of Andrographis affinis. The structures elucidated by spectral chemical studies.
Abstract A facile, efficient, and green synthesis of bis-indolyl tris-indolyl methanes has been developed by one-pot condensation indole with structurally diverse aldehydes ketones in the presence poly(ethylene glycol)–bound sulfonic acid as catalyst at room temperature.
Novel quinazolinone based α-glucosidase inhibitors have been developed. For this purpose a virtual screening model has generated and validated utilizing acarbose as inhibitor. Homology modeling, docking, were successfully employed to discover set of structurally diverse compounds active against α-glucosidase. A search 3D database containing 22 500 small molecules using the structure yielded ten possible candidates. All candidates N-3-pyridyl-2-cyclopropyl quinazolinone-4-one derivatives,...
Abstract Phase equilibrium data are presented for the ternary liquid systems, namely, acetic acid‐water‐hexane, ethylene glycol‐water‐ n ‐butanol, glycol‐water‐ethyl methyl ketone, and ethyl ketone‐water‐ cyclo hexane. The tie‐line all systems have been analysed by methods of correlation Othmer & Tobias Hand, fitted reasonably with respective plots. For system tie‐lines, when produced beyond binodal curve, meet at a point on extended base line diagram this facilitates interpolation...
Two new homoisoflavonoids, (E)-7-methoxy-3-(4′-methoxybenzylidene)chroman-4-one (1) and (E)-7-hydroxy-3-(3′,4′,5′-trimethoxybenzylidene)chroman-4-one (5), along with three known homoisoflavonoids (Z)-7-hydroxy-3-(4′-methoxybenzylidene)chroman-4-one (isobon ducellin) (2), (E)-7-hydroxy-3-(4′-methoxybenzylidene)chroman-4-one (bonducellin) (3) (E)-7-hydroxy-3-(2′,4′-dimethoxybenzylidene)chroman-4-one (4) were isolated from the whole plant of Caesalpinia pulcherrima. The structures these...
Two naturally occurring homoisoflavonoids (3h,3i) and nine analogs (2a-2i) have been synthesised from appropriately substituted phenols thorough 1-(2-hydroxyphenyl)-3phenylpropane-1-ones (1a-1i).The anti-oxidant anti-fungal activities were determined by superoxide (NBT) Agar cup method respectively.The reaction of with triethylorthoformate 70% perchloric acid followed aqueous hydrolysis the intermediate perchlorates, corresponding homoisoflavones are obtained in excellent yields.Thereafter,...