- Fungal Biology and Applications
- Entomopathogenic Microorganisms in Pest Control
- Insect Resistance and Genetics
- Phytochemistry and Bioactive Compounds
- Phytochemistry and Biological Activities
- Natural product bioactivities and synthesis
- Viral Infectious Diseases and Gene Expression in Insects
- Enzyme Production and Characterization
- Insect and Pesticide Research
- Protein Hydrolysis and Bioactive Peptides
- Phytochemical Studies and Bioactivities
- Chemical synthesis and alkaloids
- Cancer Cells and Metastasis
- Chromatography in Natural Products
- Bioactive Compounds and Antitumor Agents
- Microbial Natural Products and Biosynthesis
- Microfluidic and Capillary Electrophoresis Applications
- Sesquiterpenes and Asteraceae Studies
- Medicinal Plants and Bioactive Compounds
- Helicobacter pylori-related gastroenterology studies
- Andrographolide Research and Applications
- Protein purification and stability
- Algal biology and biofuel production
- Synthesis and biological activity
- Phytase and its Applications
Kaohsiung Medical University
2025
Kaohsiung Medical University Chung-Ho Memorial Hospital
2025
National Taitung University
2015-2024
Beijing University of Chemical Technology
2023
Chaoyang University of Technology
2012-2022
Institute of Biomedical Science
2016
Johns Hopkins Medicine
2012
Johns Hopkins University
2012
Chung Shan Medical University
2010
Taichung Veterans General Hospital
2010
Antrodia camphorata is a unique mushroom of Taiwan, which has been used as traditional medicine for protection diverse health-related conditions. In an effort to translate this Eastern into Western-accepted therapy, great deal work carried out on A. camphorata. This review discusses the biological activities crude extracts and main bioactive compounds The list bioactivities huge, ranging from anti-cancer vasorelaxation others. Over 78 consisting terpenoids, benzenoids, lignans, benzoquinone...
Oral squamous cell carcinoma (OSCC) is among the most commonly diagnosed malignancies in world. Patients with OSCC often develop treatment resistance, resulting a poor prognosis. Mounting evidence indicates that interactions between cancerous cells and other components of tumor microenvironment (TME) determine their response to treatment. Herein, we examined role cancer stem cell-derived extracellular vesicles (CSC_EVs) generated from CAL27 SCC-15 development cisplatin (CDDP) resistance. We...
Background: This study investigated the wound-healing potential of hispolon, a polyphenolic pigment derived from medicinal mushrooms, under diabetic conditions using both in vitro and vivo models. Methods: In assays, L929 fibroblast cells exposed to high glucose (33 mmol/L) were treated with hispolon at concentrations 2.5, 5, 7.5, or 10 μmol/L. streptozotocin-induced rats excision wounds received daily topical applications 0.2 g 5% (w/w) ointment. Results: Hispolon improved cell viability;...
ABSTRACT A process designed for the characteristics of rapeseed and canola proteins was developed, consisting extraction oil‐free meal at pH 10.5–12.5, isoelectric precipitation to recover ultrafiltration followed by diafiltration concentrate purify remaining acid‐soluble proteins. These steps complement one another yield three products with excellent protein recovery. Isoelectric soluble isolates containing 87–104% (N × 6.25) a residue were obtained from meal. All five types fractions free...
Abstract Herbal medicines are now attracting attention as potential sources of anticancer agents. Andrographis paniculata is a traditionally used herb in Indian and Chinese herbal medicine. Phytochemical investigation the ethanol extract aerial parts this resulted isolation 14 compounds including flavonoids labdane diterpenoids. This first compound 6 from natural source, A. rich source for molecule andrographolide (9, 1.375%, w/w). The structures isolated were established by means spectral...
Lung cancer is the leading cause of deaths worldwide and current therapies fail to treat this disease in majority cases. Antrodia camphorata a medicinal mushroom being widely used as food dietary supplement for prevention. The sesquiterpene lactone antrocin most potent among >100 secondary metabolites isolated from A. . However, molecular mechanisms antrocin-mediated anticancer effects remain unclear. In study, we found that inhibited cell proliferation two non-small-cell lung cells, namely...
In the continuing search for novel antiinflammatory agents, six flavonoids, namely kaempferol (1), ombuin (2), 7,4'-dimethyl ether 3-O-beta-D-glucopyranoside (3), (4), isorhamnetin (5) and hesperidin (6), together with one triterpene caffeate, 3beta-trans-(3,4-dihydroxycinnamoyloxy)olean-12-en-28-oic acid (7) were isolated from non-woody aerial parts of Bauhinia variegata. Compounds 1-7 evaluated as inhibitors some macrophage functions involved in inflammatory process. These seven compounds...