A5061772414- Glioma Diagnosis and Treatment
- Meningioma and schwannoma management
- Chromatin Remodeling and Cancer
- Head and Neck Surgical Oncology
- Inflammatory Myopathies and Dermatomyositis
- Neurofibromatosis and Schwannoma Cases
- Cancer, Hypoxia, and Metabolism
- Parkinson's Disease Mechanisms and Treatments
- Radiomics and Machine Learning in Medical Imaging
- Neurogenetic and Muscular Disorders Research
- MicroRNA in disease regulation
- Neuroendocrine Tumor Research Advances
- Biochemical Analysis and Sensing Techniques
- Medical Imaging Techniques and Applications
- Cancer-related Molecular Pathways
- Melanoma and MAPK Pathways
- Ferroptosis and cancer prognosis
- Mitochondrial Function and Pathology
- Computational Drug Discovery Methods
- Regulation of Appetite and Obesity
- Traumatic Brain Injury and Neurovascular Disturbances
- Brain Tumor Detection and Classification
- Peripheral Neuropathies and Disorders
- Hypertrophic osteoarthropathy and related conditions
- Muscle Physiology and Disorders
University of Utah
2021
University of Debrecen
2013-2019
// Balázs Murnyák 1 and Tibor Hortobágyi Division of Neuropathology, Institute Pathology, Faculty Medicine, University Debrecen, Hungary Correspondence to: Hortobágyi, email: Keywords : IARC TP53 Database, immunohistochemistry, mutations, cancer, p53 Received June 17, 2016 Accepted September 01, Published 08, Abstract Despite controversy on the correlation between accumulation mutational status, i mmunohistochemical (IHC) detection overexpressed protein has long...
Abstract Meningioma is among the most frequent brain tumours predominantly affecting elderly women. Epidemiological studies have shown that at age of fertility incidence relatively low. The biological behaviour meningioma in pregnancy different from other meningiomas. possible explanation rooted complex physiological changes and hormonal differences during pregnancy. increased growth observed presumably result endocrine mechanisms. These include increase progesterone, human placental...
Overexpression of PARP1 exists in various cancers, including glioblastoma (GBM). Although inhibition is a promising therapeutic target, no comprehensive study has addressed PARP1's expression characteristics and prognostic role regarding molecular heterogeneity astrocytomas GBM. Our aim was to evaluate associations with survival, WHO grade, lineage specific markers, GBM transcriptomic subtypes. We collected genomic clinical data from the latest glioma datasets The Cancer Genome Atlas...
ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Csonka T, Murnyák B, Szepesi R, et al. Assessment of candidate immunohistochemical prognostic markers meningioma recurrence. Folia Neuropathologica. 2016;54(2):114-126. doi:10.5114/fn.2016.60088. APA Csonka, T., Murnyák, B., Szepesi, R., Bencze, J., Bognár, L., & Klekner, Á. (2016). Neuropathologica, 54(2), 114-126. https://doi.org/10.5114/fn.2016.60088 Chicago Tamás, Balázs Rita János László Álmos and Tibor...
AMA Csonka T, Murnyák B, Szepesi R, Kurucz A, Klekner Á, Hortobágyi T. Original articlePoly(ADP-ribose) polymerase-1 (PARP1) and p53 labelling index correlates with tumour grade in meningiomas. Folia Neuropathologica. 2014;52(2):111-120. doi:10.5114/fn.2014.43782. APA Csonka, T., Murnyák, B., Szepesi, R., Kurucz, A., Klekner, Á., & Hortobágyi, (2014). Neuropathologica, 52(2), 111-120. https://doi.org/10.5114/fn.2014.43782 Chicago Tamás, Balázs Rita Andrea Álmos Tibor Hortobágyi. 2014....
Since the initial discovery of recurrent isocitrate dehydrogenase 1 (IDH1) mutations at Arg132 in glioma, IDH1 hotspot have been identified cholangiocarcinoma, chondrosarcoma, leukemia, and various other types cancer sporadic incidence. Studies glioma leukemia helped promote theory that are an oncogenic event drives tumorigenesis general. Through bioinformatic analysis more than 45,000 human pan-cancer samples from three independent datasets, we show here rare events but exclusively...
Tyrosine kinases play crucial roles in cellular development and tumorigenesis. kinase inhibitors (TKIs) are effective widely used drug molecules targeted cancer therapies. Altered expressions of protooncogenes tumor suppressor genes after DMBA (7,12-dimethylbenz[a]anthracene) treatment have been described as early markers induction; however their tissue-specific effects remain still unclear. Our study was aimed at examining the short-term possible antineoplastic chemopreventive a TKI...
Melanin-concentrating hormone (MCH) is a cyclic 19 amino acid orexigenic hypothalamic peptide. MCH located in the lateral and dorsal hypothalamus, as well zona incerta. In mammals increases food intake, contributes to regulation of energy balance, temperature, reproductive function, endocrine homeostasis biological rhythms. Several studies have proved significance obesity, diabetes depression. Although peptide well-characterized mouse models, much less known about its functions avians. birds...
Abstract Inclusion body myositis is a slowly progressive myopathy affecting predominantly the middle-aged and older patient population. It major form of idiopathic inflammatory myopathies which are chronic systemic autoimmune diseases characterized by symmetrical proximal muscle weakness. Unfortunately, there no effective therapy yet; however, early diagnosis essential to provide treatment options may significantly slow progression disease. In our case-based clinicopathological study...