A5107722619- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Advanced Materials and Mechanics
- Geological and Geochemical Analysis
- Heat Transfer and Optimization
- Rock Mechanics and Modeling
- Geochemistry and Geologic Mapping
- Landslides and related hazards
- Crystallography and molecular interactions
- Modular Robots and Swarm Intelligence
- Advanced Sensor and Energy Harvesting Materials
- Laser-induced spectroscopy and plasma
- Heat Transfer and Boiling Studies
- Structural Analysis and Optimization
- Chemical Thermodynamics and Molecular Structure
- Lung Cancer Treatments and Mutations
- Advanced Multi-Objective Optimization Algorithms
- Control and Dynamics of Mobile Robots
- Effects and risks of endocrine disrupting chemicals
- Refrigeration and Air Conditioning Technologies
- High-pressure geophysics and materials
- Chemical Analysis and Environmental Impact
- Plant Ecology and Soil Science
- Biomedical Text Mining and Ontologies
- Supramolecular Self-Assembly in Materials
Binzhou Medical University
2024-2025
Binzhou University
2024-2025
First Affiliated Hospital of Heilongjiang University of Chinese Medicine
2024
China University of Geosciences
2021-2024
Shandong First Medical University
2024
Harbin Institute of Technology
2022-2024
Tianjin University
2024
Kunming Medical University
2023
Kunming University of Science and Technology
2022-2023
Chinese Academy of Geological Sciences
2022
Abstract Background The objective response rate of microsatellite instability-high (MSI-H) metastatic colorectal cancer (mCRC) patients with first-line anti-programmed cell death protein-1 (PD-1) monotherapy is only 40–45%. Single-cell RNA sequencing (scRNA-seq) enables unbiased analysis the full variety cells comprising tumor microenvironment. Thus, we used scRNA-seq to assess differences among microenvironment components between therapy-resistant and therapy-sensitive groups in...
Origami-inspired metamorphous structures can adjust their shapes and mechanical behaviors according to operational requirements. However, they are typically composed of nonrigid origami, where required facet deformation complicates actuation makes them highly material dependent. In this study, we present a type origami structure modular bistable units, each which is rigid origami. The elasticity within the creases switching mountain valley crease lines enable it have bistability. resultant...
Abstract Origami-inspired design is becoming an innovative approach to create functional mechanisms with a variety of attractive features including scalability, programmability and simplicity. This paper presents the webbed-foot-inspired gripper by employing novel origami webbing structure, which generated strategically integrating several elementary Miura-ori waterbomb-ori modules. The grasping behaviour proposed webbed can be accustomed through rearranging 2D crease pattern taking...
The 797S mutation in EGFR disrupts the covalent binding of third-generation inhibitors, causing drug resistance. Currently, no clinically fully overcomes this We designed and synthesised a novel C797S-targeted inhibitor-5d by introducing structures such as cyclopropyl sulfonamide with Brigatinib lead compound; we identified target action ELISA molecular docking, tested its anti-tumor activity safety vivo vitro, well effects on cell cycle, apoptosis DNA damage. It was found that there were 10...
With regard to deep mining in metal mines, an investigation into the failure mode of fractured rock masses and their corresponding acoustic emission signal characteristics is conducted via uniaxial compression tests. Subsequently, a fractal damage renormalization group mechanical model developed explain behavior those masses. Employing bonded block (BBM) numerical simulation method, fracture process synthetic samples analyzed, thereby validating efficacy model. The simulations highlight...
The Arskartor Be-Nb-Mo deposit is the second largest Be in Chinese Altai, NW China, which hosts over 11,000 tons of BeO resource. muscovite-albite granite and rare-metal pegmatite ore district are spatially temporally coexisted both beryllium mineralized. granitic stock can be divided into a barren zone Be-mineralized zone. shows an well-developed internal including layered muscovite-quartz-albite zone, (lower) beryl-muscovite-quartz quartz core, (hanging) muscovite-quartz-microcline Beryl...
The North Qinling Orogenic Belt (NQOB) hosts many rare metal occurrences concentrated in LCT (Li–Cs–Ta) pegmatites. Nanyangshan pegmatite deposit occurs within this belt and is historically important for mining of these metals. To constrain the timing petrogenesis rare-metal-mineralized pegmatite, a systematic study U–Pb ages columbite–group minerals (CGM), cassiterite, zircon, as well Hf isotopes chemical analyses zircon were undertaken No. 703 rare-metal pegmatite. This identifies three...
Abstract Reconfigurable mechanisms attract increasing attention for the characteristic to change structure configurations and motion behaviors in various multifunctional systems. By drawing inspiration from a kirigami fold, this paper presents metamorphic double-loop linkage with multiple single-degree-of-freedom (DOF) reconfiguration branches, which is generated through combining two reconfigurable 6R plane-symmetric linkages. Mobility analysis of carried out terms screw-loop theory...
Due to their high kinematic characteristics, six-bar tensegrities have great potential application value in the field of robotics, especially deep space exploration robots. In this paper, an ultralight tensegrity robot is designed, and a gait planning method for continuous motion proposed. First, equilibrium matrix structure constructed, singular decomposition (SVD) performed find node coordinates internal forces structure. Two representative examples regarding structures are presented...
Through different pathways, two unsaturated thiolate‐bridged Co II complexes [Cp*Co(µ‐SR) 2 CoCp*] ( 1 , R = Ph; 3 i Pr, Cp* η 5 ‐C Me ) were successfully synthesized. Interaction of or with HBF 4 resulted in oxidative addition to give the corresponding III hydride bridged 4[BF ] and 5[BF . H NMR spectroscopic results indicate there exist conformational isomers after protonation, which substituents on thiolate ligands arranged a symmetric unsymmetric geometry. Interestingly, major sym ‐ can...
Ontology measurement is an important challenge in the field of knowledge management order to manage development ontology based systems and reduce risk project failure. Effective precondition on which meaningful useful evaluation can be made. We propose a framework normalize representation ontologies for their stable measurement, where semantic enriched model (SERM) proposed as unique ontologies. By normalization framework, we provide four-step procedure extract entities calculate measures...