- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiac electrophysiology and arrhythmias
- Cardiac pacing and defibrillation studies
- ECG Monitoring and Analysis
- Venous Thromboembolism Diagnosis and Management
- Pulmonary Hypertension Research and Treatments
- Polyomavirus and related diseases
- Cardiovascular Disease and Adiposity
- Renal Diseases and Glomerulopathies
- Lipoproteins and Cardiovascular Health
- Genomic variations and chromosomal abnormalities
- Extraction and Separation Processes
- Eosinophilic Disorders and Syndromes
- Immunodeficiency and Autoimmune Disorders
- Inflammatory Myopathies and Dermatomyositis
- Cardiac Valve Diseases and Treatments
- Cleft Lip and Palate Research
- Electrochemical Analysis and Applications
- dental development and anomalies
- Cardiovascular Function and Risk Factors
- Cardiovascular Effects of Exercise
- Ion channel regulation and function
- Nephrotoxicity and Medicinal Plants
- Pericarditis and Cardiac Tamponade
Dalhousie University
2018-2021
Queen Elizabeth II Health Sciences Centre
2018-2020
Baylor University Medical Center
2019
Universitair Ziekenhuis Brussel
2016-2018
Vrije Universiteit Brussel
2016-2018
AZ Sint-Jan
2015-2017
Ghent University
2017
University of Oklahoma Health Sciences Center
2017
Heart Rhythm Society
2016
Hospital for Tropical Diseases
1934-2015
Background— Pulmonary vein reconnection (PVR) still determines recurrences of atrial fibrillation after contact force (CF)–guided pulmonary isolation. We studied whether acute PVR (adenosine and waiting time) late (at repeat) are explained by incomplete transmurality contiguity within the deployed radiofrequency circle. Methods Results— analyzed 42 CF-guided ipsilateral isolation procedures. For each tag circle, we collected data reflecting lesion depth (time application, power, impedance...
In this double centre, retrospective study, we aimed to analyse the 1-year efficacy and safety of cryoballoon ablation (CB-A) in patients older than 75 years compared with those younger 75-years old. Fifty-three consecutive aged or drug-resistant paroxysmal AF (PAF) who underwent pulmonary vein isolation (PVI) by means second generation CB-A, were 106 <75 years. The mean age study group (>75 years) was 78.19 ± 2.7 58.97 8.5 control group. At follow-up global success rate 83.6% did not...
To facilitate ablation of ventricular tachycardia (VT), an automated localization system to identify the site origin left activation in real time using 12-lead ECG was developed. The objective this study prospectively assess its accuracy.The consists 3 steps: (1) segment based on population templates, (2) population-based within a segment, and (3) patient-specific localization. Localization error assessed by distance between known reference estimated site.In 19 patients undergoing 21...
Atrial fibrillation is the most common clinically encountered arrhythmia and catheter ablation has emerged as a viable treatment option in drug-refractory cases. Pulmonary vein isolation widely regarded cornerstone for successful outcomes paroxysmal AF given that pulmonary veins are frequent source of triggering. Ablation strategies persistent less well defined. Mapping complex fractionated electrograms (CFAEs) one strategy been proposed means modifying atrial substrate thought to be...
Pulmonary vein isolation (PVI) has been demonstrated more effective in young patients, which the substrate for atrial fibrillation (AF) is probably confined to pulmonary potentials. The present study sought focus on midterm outcomes patients under 40 years having undergone PVI with Cryoballoon Advance because of drug resistant AF.Between June 2012 and December 2015, 57 ablation (CB-A) below age AF our centre were retrospectively analysed considered analysis. All underwent this procedure 28...
Reconduction across an ablation line is a common reason for arrhythmia recurrence over time. The hybrid procedure combines epicardial of the pulmonary vein (PV) and creation box lesion with endocardial touch-ups any electrical gaps. A high contact force (CF) between tip cardiac tissue may increase risk thrombus formation, catheter charring, steam pop even perforation. CF monitoring significant new parameter titration creating adequate lesion.Thirty-eight consecutive patients underwent using...
The therapeutical management of atrial fibrillation (AF) in the setting Brugada syndrome (BS) might be challenging as many antiarrhythmic drugs (AADs) with sodium channel blocking properties lead to development ventricular arrhythmias. This study sought evaluate clinical outcome a consecutive series patients BS having undergone pulmonary vein (PV) isolation by means radiofrequency (RF) or cryoballoon (CB) ablation and efficacy catheter for preventing inappropriate interventions delivered...
Aims Femoral venous pressure waveform (VPW) analysis has been recently described as a novel method to assess phrenic nerve function during atrial fibrillation ablation procedures by means of the cryoballoon technique. In this study, we sought evaluate feasibility and effectiveness technique, with respect incidence injury (PNI), in comparison traditional abdominal palpation technique alone. Methods Consecutive patients undergoing second-generation (CB-A) from June 2014 2015 were...
The predictive value of induction studies after catheter ablation for atrial fibrillation (AF) is still debatable. To date, these have not been implemented in patients cryoballoon (CB) ablation. Our aim was to analyse the clinical AF treated by second generation CB paroxysmal AF.Seventy underwent at first an isoproterenol challenge pulmonary vein (PV) isolation assess and early PV reconnections (EPVR). Patients without EPVR were evaluated premature contraction (PAC) induction; ectopy...
Gal et al. [1] reported the results of 50 patients treated for atrial fibrillation (AF) using endoscopic laser balloon ablation system (EAS) in Netherlands, who were recruited study between December 2011 and 2013. The second-generation EAS uses a compliant to improve balloon/tissue contact, which improves energy delivery create consistent lesions and, ultimately, achieve durable pulmonary vein (PV) isolation. study’s mean procedure fluoroscopy time 171 36 min, respectively. Temporary phrenic...
Abstract Background Catheter ablation is an established therapy for atrial fibrillation but limited by recurrence; efforts have been made to identify biomarkers that predict recurrence. We investigated the effect of baseline NT-proBNP on AF recurrence following catheter in patients randomized aggressive (< 120/80 mmHg) or standard blood pressure management 140/90 Substrate Modification with Aggressive Blood Pressure Control trial (SMAC-AF). Methods The SMAC-AF study included 173 resistant...