- Colorectal Cancer Screening and Detection
- Chronic Myeloid Leukemia Treatments
- Vascular Tumors and Angiosarcomas
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Porphyrin Metabolism and Disorders
- Cutaneous lymphoproliferative disorders research
- Medicine and Dermatology Studies History
- Bone and Joint Diseases
- Autoimmune Bullous Skin Diseases
- Cell Adhesion Molecules Research
- Orthopedic Infections and Treatments
- Cardiac tumors and thrombi
- Nonmelanoma Skin Cancer Studies
- Diverticular Disease and Complications
- Diet and metabolism studies
- Pancreatic and Hepatic Oncology Research
- Global Cancer Incidence and Screening
- Oral and gingival health research
- Dietary Effects on Health
- Skin and Cellular Biology Research
- Systemic Lupus Erythematosus Research
- Occupational and environmental lung diseases
- Cardiac electrophysiology and arrhythmias
- Obstructive Sleep Apnea Research
Dalhousie University
2019-2024
University of Ottawa
2024
Queen Elizabeth II Health Sciences Centre
2020
Memorial University of Newfoundland
2015-2016
UCLouvain
1991
Cliniques Universitaires Saint-Luc
1988-1991
Johns Hopkins University
1985-1989
Johns Hopkins Medicine
1985-1986
Abstract One hundred sixty‐nine patients with radio‐graphic or histologic evidence of ischemic necrosis bone (INB) were evaluated. Ninety‐nine (59%) the 169 had multiple sites INB, 310 bones affected. Two sixty‐three (85%) symptomatic. Routine radiography produced negative findings in 58 (20%) histologically confirmed INB. Results hemodynamic studies, including baseline marrow pressure, saline stress test, and/or intraosseous venography, abnormal 243 (94%) 259 so Most importantly, studies...
To facilitate ablation of ventricular tachycardia (VT), an automated localization system to identify the site origin left activation in real time using 12-lead ECG was developed. The objective this study prospectively assess its accuracy.The consists 3 steps: (1) segment based on population templates, (2) population-based within a segment, and (3) patient-specific localization. Localization error assessed by distance between known reference estimated site.In 19 patients undergoing 21...
Background. The purpose of this study is to determine if colonoscopy quality associated with the annual case volume endoscopists. Methods. A retrospective cohort was performed on 3235 patients who underwent in city St. John's, NL, between January and June 2012. Data collected included completion (CCR) adenoma detection rates (ADR). Endoscopists were divided into quintiles based volume. To account for potential confounding variables, univariate analyses followed by multivariable logistic...
In 2012 the Canadian Association of Gastroenterology published 19 indicators safety compromise. We studied incidence these by reviewing all colonoscopies performed in St. John's, NL, between January 1, 2012, and June 30, 2012. Results. A total 3235 were included. Adverse events are as follows. Medication-related includes use reversal agents 0.1%, hypoxia 9.9%, hypotension 15.4%, hypertension 0.9%. No patients required CPR or experienced allergic reactions laryngospasm/bronchospasm. The...
Abstract Allogeneic hematopoietic cell transplantation (HCT) is the only curative therapy for myelofibrosis (MF) and recommended patients with higher risk disease. However, there a of early mortality, optimal timing unknown. JAK inhibitor (JAKi) may offer durable improvement in symptoms, splenomegaly quality life. The aim this multicentre, retrospective observational study was to compare outcomes aged 70 years or below MF chronic phase who received upfront JAKi vs. HCT dynamic international...
A case of Gottron’s syndrome or symmetrical progressive erythrokeratoderma is presented. Typical, erythematosquamous lesions are limited to the limbs and face; disease appeared at 4 months stabilized 3 years. The histological study discovers only nonspecific granular layer alterations.The ultrastructural investigation reveals an important intercellular edema a moderate cytoplasmic vacuolization in basal prickle cell stratum corneum; wandering lymphocytes also observed. association with...
The ultrastructural aspects of nucleus and cytoplasm tumor cells the interstitial material dermatofibrosarcoma protuberans are described in detail, especially very peculiar labyrinthic nucleus. Opinions about its development reviewed; some, such as melanocytic, neural, histiocytic smooth muscle proliferation, might be discarded. myofibroblast appears most probable stem cell.
A 61-year-old man consulted for two long-standing ulcerations on the scalp and one nose, following an acute vascular disorder of brain stem (Wallenberg's syndrome). The aetiology pathogenesis neurotrophic ulcers are briefly discussed.
In the most malignant areas of angiosarcomas, collagen bundles impinge on endothelial cells, sink into ‘collagen pockets’ that migrate throughout cytoplasm and build up cord-like bridges within lumen.