- Viral-associated cancers and disorders
- Chronic Myeloid Leukemia Treatments
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- CNS Lymphoma Diagnosis and Treatment
- Blood groups and transfusion
- Histiocytic Disorders and Treatments
- Cutaneous lymphoproliferative disorders research
- Lymphoma Diagnosis and Treatment
- Kruppel-like factors research
- Autoimmune and Inflammatory Disorders Research
- Renal Diseases and Glomerulopathies
- Fungal Infections and Studies
- Complement system in diseases
St. Paul's Hospital
2020-2024
University of British Columbia
2020-2024
Royal Columbian Hospital
2023
Prior studies have suggested that immune thrombotic thrombocytopenic purpura (iTTP) may display seasonal variation; however, methodologic limitations and sample sizes diminished the ability to perform a rigorous assessment. This 5-year retrospective study assessed epidemiology of iTTP determined whether it displays pattern. Patients with both initial relapsed (defined as disintegrin metalloprotease thrombospondin type motifs 13 activity <10%) from 24 tertiary centers in Australia, Canada,...
Abstract Allogeneic hematopoietic cell transplantation (HCT) is the only curative therapy for myelofibrosis (MF) and recommended patients with higher risk disease. However, there a of early mortality, optimal timing unknown. JAK inhibitor (JAKi) may offer durable improvement in symptoms, splenomegaly quality life. The aim this multicentre, retrospective observational study was to compare outcomes aged 70 years or below MF chronic phase who received upfront JAKi vs. HCT dynamic international...
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is an aggressive hematologic malignancy which associated with a distinctive morphologic appearance. However, the morphology not specific, and diagnostic characterization requires integration of immunophenotypic genetic testing. We herein report case 35-year-old female patient who presented worsening cytopenia. A bone marrow aspirate identified medium-sized blastic cells perinuclear microvacuoles (“pearl neckless”). Occasional blasts...