A5046648199- Platelet Disorders and Treatments
- Complement system in diseases
- Renal Diseases and Glomerulopathies
- Mycobacterium research and diagnosis
- Blood groups and transfusion
- Heparin-Induced Thrombocytopenia and Thrombosis
- Neutropenia and Cancer Infections
- Tuberculosis Research and Epidemiology
- Infectious Diseases and Tuberculosis
- Clinical Laboratory Practices and Quality Control
- Hematological disorders and diagnostics
- Otolaryngology and Infectious Diseases
- Plant Pathogens and Fungal Diseases
- Antifungal resistance and susceptibility
- Streptococcal Infections and Treatments
- Multiple Myeloma Research and Treatments
- Research on Leishmaniasis Studies
- Intramuscular injections and effects
- Fungal Infections and Studies
- Bacterial Identification and Susceptibility Testing
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Sepsis Diagnosis and Treatment
University of Iowa Health Care
2024-2025
University of Iowa
2023-2025
University of Iowa Hospitals and Clinics
2020-2023
Abstract Background Heparin-induced thrombocytopenia (HIT) is a potentially life-threatening adverse drug reaction with numerous diagnostic challenges. Diagnosis of HIT begins 4T score clinical assessment, followed by laboratory testing for those not deemed low risk. Laboratory includes screening [enzyme-linked immunosorbent assay (ELISA)] and confirmatory [serotonin release (SRA)] assays, wherein SRA can be pursued following positive ELISA result. These tests aid diagnosis HIT, but also...
ABSTRACT Immune thrombotic thrombocytopenic purpura (iTTP) is characterized by microangiopathic hemolytic anemia, thrombocytopenia, and microvascular occlusion secondary to acquired ADAMTS13 deficiency. Contemporary data regarding iTTP treatment practices in the US, including use of caplacizumab, are lacking. We aimed characterize demographics therapies, medications apheresis practices, patients with US. retrospectively analyzed cases at 15 sites US that provide comprehensive care for iTTP....
Prior studies have suggested that immune thrombotic thrombocytopenic purpura (iTTP) may display seasonal variation; however, methodologic limitations and sample sizes diminished the ability to perform a rigorous assessment. This 5-year retrospective study assessed epidemiology of iTTP determined whether it displays pattern. Patients with both initial relapsed (defined as disintegrin metalloprotease thrombospondin type motifs 13 activity <10%) from 24 tertiary centers in Australia, Canada,...
An immunocompetent man in his 40s presented with 3 months of mid-thoracic back pain which progressed to include progressive paraesthesias and lower extremity weakness. Investigations revealed thoracic spine osteomyelitis signs cord compression. He underwent neurosurgical intervention, including laminectomy, spinal decompression partial resection an epidural mass. Initial intraoperative biopsy surgical pathology results were concerning for acid-fast bacillus as the causative pathogen, patient...
We analyzed blood-culture practices to characterize the utilization of Infectious Diseases Society America (IDSA) recommendations related catheter-related bloodstream infection (CRBSI) blood cultures. Most patients with a central line had only peripheral Increasing CRBSI guidelines may improve clinical care, but also affect other quality metrics.
Journal Article A 58-Year-Old Male With a Chronic Sore Throat Get access Arya Zandvakili, Zandvakili Division of General Internal Medicine, Department University Iowa Hospitals and Clinics, City, Iowa, USA Correspondence: A. 52242, 200 Hawkins Drive, E326-2GH (arya-zandvakili@uiowa.edu). https://orcid.org/0000-0001-8031-8067 Search for other works by this author on: Oxford Academic PubMed Google Scholar Takaaki Kobayashi, Kobayashi Infectious Diseases, Kristen Seligman, Seligman...
Abstract Background Broad-range metagenomic cell-free DNA testing (Karius®) can identify a variety of pathogens from single blood sample to help in diagnosis deep seated and bloodstream infections. Few studies have evaluated the impact Karius on clinical decision making when compared more conventional diagnostic methods. Methods We performed retrospective cohort study adult patients who had tests at University Iowa Hospitals Clinics between 01/2020 10/2021. Chart review was conducted obtain...