A5046372032- Antifungal resistance and susceptibility
- Antimicrobial Resistance in Staphylococcus
- Fungal Infections and Studies
- Bacterial Identification and Susceptibility Testing
- Antibiotic Use and Resistance
- Streptococcal Infections and Treatments
- Infection Control in Healthcare
- Infection Control and Ventilation
- Pneumocystis jirovecii pneumonia detection and treatment
- Pneumonia and Respiratory Infections
- Clostridium difficile and Clostridium perfringens research
- Nosocomial Infections in ICU
- Mycobacterium research and diagnosis
- Nail Diseases and Treatments
- Antibiotic Resistance in Bacteria
- Infective Endocarditis Diagnosis and Management
- Bacterial biofilms and quorum sensing
- Plant Pathogens and Fungal Diseases
- Surgical site infection prevention
- COVID-19 and healthcare impacts
- Respiratory and Cough-Related Research
- Infectious Diseases and Mycology
- Respiratory viral infections research
- Tuberculosis Research and Epidemiology
- Antibiotics Pharmacokinetics and Efficacy
University of Iowa
2016-2025
University of Iowa Hospitals and Clinics
2016-2025
MaineHealth
2024-2025
Maine Medical Center
2023-2025
Maine Medical Center
2023-2024
Oregon Medical Research Center
2022-2024
University of Pittsburgh
2002-2024
Communities In Schools of Orange County
2022-2024
New York Proton Center
2007-2024
Lindsay Unified School District
2022-2024
Between January 1997 and December 1999, bloodstream isolates from 15,439 patients infected with Staphylococcus aureus 6350 coagulase-negative species (CoNS) were referred by SENTRY-participating hospitals in the United States, Canada, Latin America, Europe, Western Pacific region. S. was found to be most prevalent cause of infection, skin soft-tissue pneumonia almost all geographic areas. A notable increase methicillin (oxacillin) resistance among community-onset hospital-acquired strains...
We reexamined the attributable mortality of nosocomial candidemia 15 years after a retrospective cohort study performed at our hospital demonstrated an 38%. For all episodes between 1 July 1997 and 30 June 2001, we matched control patients with case by age, sex, date admission, underlying disease(s), length time risk, surgical procedure(s). analyzed 108 pairs. There were no statistically significant differences in procedure, or vital signs admission cases controls. The crude among was 61%...
Fluconazole in vitro susceptibility test results for 256,882 isolates of Candida spp. were collected from 142 sites 41 countries June 1997 to December 2007. Data 197,619 tested with voriconazole 2001 A total 31 different species isolated. Increased rates isolation the common non-albicans C. glabrata (10.2% 11.7%), tropicalis (5.4% 8.0%), and parapsilosis (4.8% 5.6%) noted when time periods 2000 2005 2007 compared. Investigators clinical by CLSI M44-A disk diffusion method. Overall, 90.2%...
The emergence of antifungal resistance threatens effective treatment invasive fungal infection (IFI). Invasive candidiasis is the most common health care-associated IFI. We evaluated activity fluconazole (FLU) against 20 788 isolates Candida (37 species) collected from 135 medical centers in 39 countries (1997-2016). anidulafungin, caspofungin, and micafungin (MCF) was 15 308 worldwide (2006-2016).Species identification accomplished using phenotypic (1997-2001), genotypic, proteomic methods...
ABSTRACT A surveillance program (SENTRY) of bloodstream infections (BSI) in the United States, Canada, Latin America, and Europe from 1997 through 1999 detected 1,184 episodes candidemia 71 medical centers (32 23 Europe, 9 7 Canada). Overall, 55% yeast BSIs were due to Candida albicans , followed by glabrata parapsilosis (15%), tropicalis (9%), miscellaneous spp. (6%). In 45% candidemias non- C. species. (21%) was most common species proportion highest America (55%). accounted for 60% BSI...
Bloodstream infection (BSI) organisms were consecutively collected from >200 medical centers in 45 nations between 1997 and 2016. Species identification susceptibility testing followed Clinical Laboratory Standards Institute broth microdilution methods at a central laboratory. data isolates 264,901 BSI episodes collected. The most common pathogen overall was Staphylococcus aureus (20.7%), by Escherichia coli (20.5%), Klebsiella pneumoniae (7.7%), Pseudomonas aeruginosa (5.3%), Enterococcus...
Background Recent research has demonstrated that many swine and farmers in the Netherlands Canada are colonized with MRSA. However, no studies to date have investigated carriage of MRSA among United States (U.S.). Methods We sampled nares 299 20 workers from two different production systems Iowa Illinois, comprising approximately 87,000 live animals. isolates were typed by pulsed field gel electrophoresis (PFGE) using SmaI EagI restriction enzymes, multi locus sequence typing (MLST). PCR was...
ABSTRACT There are limited data regarding the antifungal susceptibility of yeast causing vulvovaginal candidiasis, since cultures rarely performed. Susceptibility testing was performed on vaginal isolates collected from January 1998 to March 2001 429 patients with suspected candidiasis. The charts 84 multiple positive were reviewed. 593 Candida albicans ( n = 420), glabrata 112), parapsilosis 30), krusei 12), Saccharomyces cerevisiae 9), tropicalis 8), lusitaniae 1), and Trichosporon sp. 1)....
During the 12-year period from 1993 to 2004, antimicrobial susceptibility profiles of 74,394 gram-negative bacillus isolates recovered intensive care unit (ICU) patients in United States hospitals were determined by participating and collected a central location. MICs for 12 different agents using standardized broth microdilution method. The 11 organisms most frequently isolated Pseudomonas aeruginosa (22.2%), Escherichia coli (18.8%), Klebsiella pneumoniae (14.2%), Enterobacter cloacae...
The echinocandins are being used increasingly as therapy for invasive candidiasis. Prospective sentinel surveillance the emergence of in vitro resistance to among Candida sp. isolates is indicated. We determined activities anidulafungin, caspofungin, and micafungin against 5,346 (bloodstream or sterile-site) spp. collected from over 90 medical centers worldwide 1 January 2001 31 December 2006. performed susceptibility testing according CLSI M27-A2 method RPMI 1640 broth, 24-h incubation, a...
ABSTRACT Bloodstream infections due to Candida species cause significant morbidity and mortality. Surveillance for candidemia is necessary detect trends in distribution antifungal resistance. We performed prospective surveillance at 16 hospitals the State of Iowa from 1 July 1998 through 30 June 2001. Using U.S. Census Bureau Hospital Association data estimate a population denominator, we calculated annual incidence be 6.0 per 100,000 population. albicans was most common detected, but 43%...
This analysis describes the epidemiology and outcomes of invasive candidiasis caused by non-albicans species Candida in patients enrolled Prospective Antifungal Therapy Alliance (PATH Alliance) registry from 2004 to 2008. A total 2,496 with isolates were identified. The identified C. glabrata (46.4%), parapsilosis (24.7%), tropicalis (13.9%), krusei (5.5%), lusitaniae (1.6%), dubliniensis (1.5%) guilliermondii (0.4%); 111 infections involved two or more (4.4%). Non-albicans accounted for...
Fluconazole in vitro susceptibility test results for 205,329 yeasts were collected from 134 study sites 40 countries June 1997 through December 2005. Data 147,776 yeast isolates tested with voriconazole 2001 All investigators clinical by the CLSI M44-A disk diffusion method. Test plates automatically read and recorded a BIOMIC image analysis system. Species, drug, zone diameter, category, quality control quarterly. Duplicate (same patient, same species, susceptible-resistant biotype profile...
<h3>Importance</h3> Previous studies suggested that a bundled intervention was associated with lower rates of<i>Staphylococcus aureus</i>surgical site infections (SSIs) among patients having cardiac or orthopedic operations. <h3>Objective</h3> To evaluate whether the implementation of an evidence-based bundle is risk of<i>S aureus</i>SSIs in undergoing operations hip knee arthroplasties. <h3>Design, Setting, and Participants</h3> Twenty hospitals 9 US states participated this pragmatic...