Pierre‐Yves Le Roux

ORCID: 0000-0002-8534-8203
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About
Contact & Profiles
Research Areas
  • Venous Thromboembolism Diagnosis and Management
  • Medical Imaging Techniques and Applications
  • Ultrasound in Clinical Applications
  • Radiomics and Machine Learning in Medical Imaging
  • Radiation Dose and Imaging
  • Lung Cancer Diagnosis and Treatment
  • Atomic and Subatomic Physics Research
  • Advanced Radiotherapy Techniques
  • Head and Neck Cancer Studies
  • Atrial Fibrillation Management and Outcomes
  • Radiopharmaceutical Chemistry and Applications
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Medical Imaging and Pathology Studies
  • Lymphoma Diagnosis and Treatment
  • Advanced X-ray and CT Imaging
  • Acute Ischemic Stroke Management
  • Cardiac tumors and thrombi
  • Central Venous Catheters and Hemodialysis
  • Salivary Gland Tumors Diagnosis and Treatment
  • French Language Learning Methods
  • Infectious Diseases and Tuberculosis
  • Respiratory Support and Mechanisms
  • Blood Coagulation and Thrombosis Mechanisms
  • Meta-analysis and systematic reviews
  • Cardiac Imaging and Diagnostics

Université de Bretagne Occidentale
2015-2024

Centre Hospitalier Régional Universitaire de Brest
2015-2024

Inserm
2022-2024

Aix-Marseille Université
2023

Hôpital Charles-Foix
2023

Sorbonne Université
2023

Université de Rouen Normandie
2023

Université Européenne de Bretagne
2010-2022

French Clinical Research Infrastructure Network
2018-2022

Peter MacCallum Cancer Centre
2015-2021

These guidelines update the previous EANM 2009 on diagnosis of pulmonary embolism (PE). Relevant new aspects are related to (a) quantification PE and other ventilation/perfusion defects; (b) follow-up patients with PE; (c) chronic (d) description additional physiological changes leading diagnoses left ventricular heart failure (HF), obstructive disease (COPD) pneumonia. The should be reported when a mismatch one segment or two subsegments is found. For ventilation, Technegas krypton gas...

10.1007/s00259-019-04450-0 article EN cc-by European Journal of Nuclear Medicine and Molecular Imaging 2019-08-13

Posttreatment surveillance for the recurrence of head and neck squamous cell carcinoma (HNSCC) is a diagnostic challenge. Tissue distortion from radiation surgery can obscure early detection by conventional follow-up approaches such as physical examination, CT, MRI. Several studies have shown that <sup>18</sup>F-FDG PET may be an effective technique persistent, recurrent, distant metastatic HNSCC after treatment. The aim this prospective study was to determine benefits hybrid PET/CT in...

10.2967/jnumed.108.055806 article EN Journal of Nuclear Medicine 2008-12-17

Point-spread function (PSF) or PSF + time-of-flight (TOF) reconstruction may improve lesion detection in oncologic PET, but can alter quantitation resulting variable standardized uptake values (SUVs) between different PET systems. This study aims to validate a proprietary software tool (EQ.PET) harmonize SUVs across systems independent of the algorithm used.NEMA NU2 phantom data were used calculate appropriate filter for each PSF+TOF from three systems, order obtain EANM compliant recovery...

10.1007/s00259-015-3128-0 article EN cc-by European Journal of Nuclear Medicine and Molecular Imaging 2015-07-29

Purpose: Computed tomography ventilation imaging (CTVI) aims to visualize air-volume changes in the lung by quantifying respiratory motion 4DCT using deformable image registration (DIR). A problem is that DIR-based CTVI sensitive both artifacts and DIR parameters, hindering clinical validation of technique. To address this, authors present a streamlined approach estimates blood–gas exchange terms time-averaged Hounsfield unit (HU) values without relying on DIR. The purpose this study...

10.1118/1.4937599 article EN Medical Physics 2015-12-17

Silent cerebral small-vessel disease (CSVD) is defined as white matter hyperintensities, silent brain infarction, or microbleeds. CSVD responsible for future vascular events, cognitive impairment, frailty, and shorter survival. prevalence among middle-aged people living with well-controlled human immunodeficiency virus (HIV) infection (PLHIV) unknown.The French National Agency Research on AIDS Viral Hepatitis (ANRS) EP51 Microvascular Brain Retina Kidney Study (MicroBREAK; NCT02082574) a...

10.1093/cid/cix1075 article EN Clinical Infectious Diseases 2017-12-12

We aimed to identify risk factors for recurrent venous thromboembolism (VTE) after unprovoked pulmonary embolism. Analyses were based on the double-blind randomised PADIS-PE trial, which included 371 patients with a first embolism initially treated during 6 months who receive an additional 18 of warfarin or placebo and followed up 2 years study treatment discontinuation. All had ventilation/perfusion lung scan at inclusion ( i.e. anticoagulation). During median follow-up 41 months, VTE...

10.1183/13993003.01202-2017 article EN European Respiratory Journal 2018-01-01

Ventilation–perfusion (V/Q) SPECT has been reported to improve the diagnostic performance of V/Q imaging for diagnosis pulmonary embolism (PE). However, only sparse data based on an objective reference test are available, and criteria used interpretation have varied widely. Therefore, aim our study was assess using various interpretation, in comparison with a validated independent strategy. <b>Methods:</b> The included patients whom were compared results algorithm PE. scans performed after...

10.2967/jnumed.112.113639 article EN Journal of Nuclear Medicine 2013-05-01

There are currently no data published regarding the proportion of nuclear medicine centers using SPECT or SPECT/CT rather than planar ventilation/perfusion (V/Q) imaging in patients with suspected acute pulmonary embolism (PE). Furthermore, reporting criteria used for interpretation both and V/Q scans variable lacking which commonly various centers. The aim this study was to assess current practices performance lung scintigraphy across 3 different countries.A short online survey composed...

10.2967/jnumed.115.157743 article EN Journal of Nuclear Medicine 2015-07-01

The aim of the study was to assess potential interest combining a low-dose computed tomography (ldCT) ventilation/perfusion (V/Q) single-photon emission (SPECT) for diagnosis pulmonary embolism (PE). We addressed three main questions: Could ldCT be used in substitution ventilation SPECT? improve diagnostic performance V/Q provide alternative diagnoses PE?A total 393 patients previously analysed management outcome that aimed at assessing safety SPECT PE were assessed. All underwent an under...

10.1097/mnm.0000000000000351 article EN Nuclear Medicine Communications 2015-06-07

The purpose of this study was to investigate the prognostic value percentage variation metabolic tumor burden in patients with head and neck squamous cell carcinoma (HNSCC).Patients referred undergo (18) fluorodeoxyglucose (FDG) positron emission tomography (PET)-CT for staging HNSCC were included study. Using a dual-phase method, standardized uptake maximum (SUVmax), volume (MTV), total lesion glycolysis (TLG) recorded respectively used calculate retention index (RI), %ΔMTV, %ΔTLG....

10.1002/hed.24048 article EN Head & Neck 2015-03-17

Pre- and posttreatment PET comparative scans should ideally be obtained with identical acquisition processing, but this is often impractical. The degree to which differing protocols affect PERCIST classification unclear. This study evaluates the consistency of across different reconstruction algorithms whether a proprietary software tool can harmonize SUV estimation sufficiently provide consistent response classification. <b>Methods:</b> Eighty-six patients non–small cell lung cancer,...

10.2967/jnumed.115.171983 article EN Journal of Nuclear Medicine 2016-06-09

The diagnosis of wrist fractures, especially scaphoid remains a challenge because nonunion risk. Currently, new hybrid technologies are emerging such as SPECT/CT systems, which combine functional and anatomical data sets. So, we wanted to evaluate the utility in management occult carpal fractures.In this study, all patients addressed at orthopedic department Brest University Hospital for pain after trauma with initial normal plain radiographs were prospectively included. Patients but signs...

10.1097/rlu.0b013e31828164da article EN Clinical Nuclear Medicine 2013-03-22
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