- Medical Imaging Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- Advanced X-ray and CT Imaging
- Advanced Radiotherapy Techniques
- Radiopharmaceutical Chemistry and Applications
- Lymphoma Diagnosis and Treatment
- Lung Cancer Diagnosis and Treatment
- MRI in cancer diagnosis
- Advanced MRI Techniques and Applications
- Parathyroid Disorders and Treatments
- Diversity and Career in Medicine
- Sarcoma Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
- Cancer Immunotherapy and Biomarkers
- Prostate Cancer Treatment and Research
- Radiation Dose and Imaging
- Medical Imaging and Pathology Studies
- Testicular diseases and treatments
- Breast Cancer Treatment Studies
- COVID-19 and healthcare impacts
- Healthcare cost, quality, practices
- Healthcare Systems and Challenges
- Thyroid and Parathyroid Surgery
- Pancreatic and Hepatic Oncology Research
- Ovarian cancer diagnosis and treatment
Université de Caen Normandie
2015-2024
Inserm
2015-2024
Centre François Baclesse
2013-2024
Unité de recherche interdisciplinaire pour la prévention et le traitement des cancers
2022-2024
Onco Lille
2021-2022
Centre François Baclesse
2020-2022
Normandie Université
2013-2021
Centre Hospitalier Public du Cotentin
2012
We prospectively evaluated whether a strategy using point spread function (PSF) reconstruction for both diagnostic and quantitative analysis in non-small cell lung cancer (NSCLC) patients meets the European Association of Nuclear Medicine (EANM) guidelines harmonization values. The NEMA NU-2 phantom was used to determine optimal filter apply PSF-reconstructed images order obtain recovery coefficients (RCs) fulfilling EANM tumour positron emission tomography (PET) imaging (PSFEANM). PET data...
Importance Whether F18-choline (FCH) positron emission tomographic (PET)/computed (CT) scan can replace Tc99m-sestaMIBI (MIBI) single-photon (SPE)CT/CT as a first-line imaging technique for preoperative localization of parathyroid adenomas (PTA) in patients with primary hyperparathyroidism (PHPT) is unclear. Objective To compare FCH PET/CT vs MIBI SPECT/CT optimal care PHPT needing parathyroidectomy and to the proportions whom method resulted successful minimally invasive (MIP) normalization...
We investigated whether artificial intelligence (AI)-based denoising halves PET acquisition time in digital PET/CT.One hundred ninety-five patients referred for [18F]FDG PET/CT were prospectively included. Body acquisitions performed list mode. Original "PET90" (90 s/bed position) was compared to reconstructed ½-duration (45 with and without AI-denoising, "PET45AI PET45". Denoising by SubtlePET™ using deep convolutional neural networks. Visual global image quality (IQ) 3-point scores lesion...
The aim of the present study was to evaluate impact point spread function (PSF) reconstruction on quantitative values and diagnostic accuracy FDG PET/CT for nodal staging in non-small cell lung cancer.Fifty-eight consecutive examinations were reconstructed with both ordered subset expectation maximization (OSEM) PSF algorithms. Two readers independently performed a randomized blinded review gave status (N0, N1, N2, or N3) each PET data set. When discordant, consensus reached third reader....
Background Early reports show the unequal effect COVID-19 pandemic might have on men versus women engaged in medical research. Purpose To investigate whether has had an impact scientific publishing by female physicians imaging. Materials and Methods The authors conducted a descriptive bibliometric analysis of gender first last manuscripts submitted to top 50 imaging journals from March May 2020 (
Our purpose was to evaluate the diagnostic and prognostic value of skeletal textural features (TFs) on baseline FDG PET in diffuse large B cell lymphoma (DLBCL) patients.Eighty-two patients with DLBCL who underwent a bone marrow biopsy (BMB) scan between December 2008 2015 were included. Two readers blinded BMB results visually assessed images for involvement (BMI) consensus, third observer drew volume interest (VOI) encompassing axial skeleton pelvis, which used assess TFs. ROC analysis...
Pre- and posttreatment PET comparative scans should ideally be obtained with identical acquisition processing, but this is often impractical. The degree to which differing protocols affect PERCIST classification unclear. This study evaluates the consistency of across different reconstruction algorithms whether a proprietary software tool can harmonize SUV estimation sufficiently provide consistent response classification. <b>Methods:</b> Eighty-six patients non–small cell lung cancer,...
The clinical validation of the EARL harmonization program for standardised uptake value (SUV) metrics is well documented; however, its potential defining metabolic active tumour volume (MATV) has not yet been investigated. We aimed to compare delineation MATV on images reconstructed using conventional ordered subset expectation maximisation (OSEM) with those point spread function modelling (PSF-reconstructed images), and either optimised diagnostic (PSF) or filtered meet EANM/EARL...
PurposeTo seek for the minimal duration per bed position with a digital PET system without compromising image quality and lesion detection in patients requiring fast 18F-FDG imaging.Materials methods19 cancer experiencing pain or dyspnea 9 pediatric were scanned on Vereos system. List mode data reconstructed decreasing time frame down to 10 s position. Noise was evaluated liver, blood pool muscle, using target-to-background ratios. Five readers recorded quality, number of clinically relevant...
Abstract Background The common endocrine disorder primary hyperparathyroidism (PHPT) can be cured by surgery. Preoperative localization of parathyroid adenoma (PTA) imaging is a prerequisite for outpatient minimally invasive parathyroidectomy (MIP). Compared to inpatient bilateral cervical exploration (BCE) which performed if inconclusive, MIP superior in terms cure and complication rates less costly. procedure F18-choline (FCH) PET/CT outperforms Tc99m-sestaMIBI (MIBI) SPECT/CT PTA...
When evaluating 18F-FDG PET images with the Deauville score (DS), quantification of tumor and reference organs limits problem optical misinterpretation. Compared conventional reconstruction algorithms, point-spread function (PSF) modeling increases SUVs significantly in tumors but only moderately liver, which could affect DS. We investigated whether choice algorithm affects DS discordance capability to stratify lymphoma patients. Methods: Overall, 126 patients diffuse large B-cell were...
The aim of this study is to determine if the choice 18F-FDG-PET protocol, especially matrix size and reconstruction algorithm, importance discriminate between immunohistochemical subtypes (luminal versus non-luminal) in breast cancer with textural features (TFs). Forty-seven patients referred for staging framework a prospective were reviewed as part an ancillary study. In addition standard PET imaging (PSFWholeBody), high-resolution acquisition was performed reconstructed OSEM PSF...
This study evaluates the consistency of PET evaluation response criteria in solid tumours (PERCIST) and European Organisation for Research Treatment Cancer (EORTC) classification across different reconstruction algorithms whether aligning standardized uptake values (SUVs) to Association Nuclear Medicine acquisition (EANM)/EARL standards provides more consistent classification.
Introduction We aimed to investigate whether 18 F-FDG PET metabolic heterogeneity reflects the of estrogen receptor (ER) and progesterone (PR) expressions within luminal non-metastatic breast tumors if it could help in identifying patients with worst event-free survival (EFS). Materials methods On 38 high-resolution bed positions, a single physician drew volumes interest encompassing extract SUV max , histogram parameters textural features. High-resolution immunochemistry (IHC) scans were...