A5011958202- Lung Cancer Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
- Lung Cancer Research Studies
- HIV Research and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Antimicrobial Peptides and Activities
- Cancer, Hypoxia, and Metabolism
- Cancer, Stress, Anesthesia, and Immune Response
- Brain Metastases and Treatment
- Gastric Cancer Management and Outcomes
- Cancer Research and Treatments
- Autophagy in Disease and Therapy
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Inflammatory mediators and NSAID effects
- S100 Proteins and Annexins
- Metastasis and carcinoma case studies
- Advanced X-ray and CT Imaging
- RNA Interference and Gene Delivery
- Glycosylation and Glycoproteins Research
Beijing Chest Hospital
2016-2023
Capital Medical University
2020-2023
Frederick National Laboratory for Cancer Research
2020-2021
National Cancer Institute
2020-2021
Center for Cancer Research
2020-2021
Cancer Research Institute of the Slovak Academy of Sciences
2021
Fourth Hospital of Hebei Medical University
2011
Hebei Medical University
2011
ABSTRACT Host-derived antimicrobial peptides play an important role in the defense against extracellular bacterial infections. However, capacity of derived from macrophages as potential antibacterial effectors intracellular pathogens remains unknown. In this study, we report that normal (wild-type, WT) mouse increased their expression cathelin-related peptide (CRAMP, encoded by Camp) after infection viable E. coli or stimulation with inactivated and its product lipopolysaccharide (LPS), a...
Disruption in mucins (MUCs) is involved cancer development and metastasis thus used as a biomarker. Non‑small cell lung carcinoma (NSCLC) characterized by heterogeneous genetic epigenetic alterations. Lung adenocarcinoma (LUAD) squamous (LUSC) are the two primary subtypes of NSCLC that require different therapeutic interventions. Here, we report distinct expression alterations mucin 22 (<em>MUC22</em>), new MUC family member, LUSC vs. LUAD. In lines tissues, <em>MUC22</em> was downregulated...
Chronic inflammation is a causative factor of many cancers, although it originally acts as protective host response to the loss tissue homeostasis. Many inflammatory conditions predispose susceptible cells, most which are epithelial origin, neoplastic transformation. There close correlation between digestive tract (DT) cancer and chronic inflammation, such esophageal adenocarcinoma associated with Barrett’s esophagus, helicobacter pylori infection cause stomach cancer, hepatitis leading...
The objective of the present study was to investigate role postoperative radiotherapy (PORT) after radical resection stage IIIA-N2 non-small cell lung cancer (NSCLC). Subgroups patients who benefited from PORT were evaluated. A retrospective review 288 consecutive with resected pIIIA-N2 NSCLC at Beijing Chest Hospital (Beijing, China) performed. Of these patients, 61 received PORT. divided into and non-PORT groups according treatment received. baseline characteristics two patient balanced...
Abstract Background The beneficial effect of postoperative radiotherapy (PORT) on completely resected pathological IIIA-N2 (pIIIA-N2) non-small cell lung cancer (NSCLC) has been a subject interest with controversy. aim the study was to distinguish clinical efficacy PORT adenocarcinoma (LADC) and squamous carcinoma (LSCC) among pIIIA-N2 NSCLC. Patients methods Between October 2010 September 2016, 288 consecutive patients NSCLC at Beijing Chest Hospital were retrospectively analyzed, which...
There is no high-level evidence for the time of whole brain radiotherapy (WBRT) patients with epidermal growth factor receptor (EGFR)-mutated non-small cell lung cancer (NSCLC) and metastases. The aim this study to assess appropriate timing WBRT EGFR-mutated NSCLC metastases (BM).There were 78 diagnosed BM in Beijing Chest Hospital between August 2009 May 2015. 48 untreated who received both EGFR-tyrosine kinase inhibitors (TKIs) therapy. Prognostic factors intracranial progression-free...
Abstract Host-derived antimicrobial peptides play an important role in the defense against extracellular bacterial infections. However, capacity of derived from macrophages as potential antibacterial effectors intracellular pathogens remains unknown. In this study, we report that normal (wild type, WT) mouse increased their expression cathelicidin-related peptide (CRAMP) after infection by viable E. coli or stimulation with inactivated and its product LPS, a process involving activation...
Abstract Background. The beneficial effect of postoperative radiotherapy (PORT) on resected pathological IIIA-N2 (pIIIA-N2) non-small cell lung cancer (NSCLC) has been a subject interest with controversy. aim this study was to distinguish the clinical efficacy PORT adenocarcinoma (LADC) and squamous carcinoma (LSCC) among pIIIA-N2 NSCLC. Methods. Between October 2010 September 2016, 288 consecutive patients NSCLC at Beijing Chest Hospital were retrospectively analyzed. There 194 cases (ADC),...
Abstract Background. The objective of this study was to investigate the role postoperative radiotherapy (PORT) after radical resection stage IIIA-N2 non-small cell lung cancer (NSCLC). Subgroups patients who benefited from PORT were evaluated. Methods. A retrospective review 288 consecutive with resected pIIIA-N2 NSCLC at Beijing Chest Hospital performed. Sixty-one additionally received PORT. divided into and non-PORT groups according treatment received. Baseline characteristics two patient...