A5003120434- Inflammatory mediators and NSAID effects
- Lung Cancer Treatments and Mutations
- Salivary Gland Tumors Diagnosis and Treatment
- RNA modifications and cancer
- Lung Cancer Diagnosis and Treatment
- Ear and Head Tumors
- Estrogen and related hormone effects
- Endometrial and Cervical Cancer Treatments
- Cancer-related molecular mechanisms research
- Head and Neck Cancer Studies
- Advanced Radiotherapy Techniques
- Advanced X-ray and CT Imaging
- Effects of Radiation Exposure
- Radiomics and Machine Learning in Medical Imaging
- Ovarian cancer diagnosis and treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Glioma Diagnosis and Treatment
- Tracheal and airway disorders
- Cancer survivorship and care
- Cancer, Lipids, and Metabolism
- Nonmelanoma Skin Cancer Studies
- Synthesis of β-Lactam Compounds
- Frailty in Older Adults
- Neuroblastoma Research and Treatments
- Emotions and Moral Behavior
Lanzhou University
2008-2025
Hebei Normal University
2025
First Hospital of Lanzhou University
2008-2024
Beijing City University
2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2017-2020
Xinjiang Medical University
2018
University of East Anglia
2012
Ontario Institute for Cancer Research
2007
University Health Network
2007
AbstractCyclooxygenase-2 (COX-2) plays a crucial role in the development and invasion of gastric cancer. COX-2 inhibitors have been shown to be chemopreventive against gastrointestinal cancers. In vitro studies suggested that mechanisms may related induction apoptosis inhibition angiogenesis. also impact on E-cadherin. our study we investigate effect Celecoxib expression E-cadherin serum soluble E-cadherin, as well angiogenesis patients with Fifty nine cancer were randomly divided into 2...
Non-small cell lung cancer (NSCLC) exhibits radioresistance to conventional rays, due its DNA damage repair systems. NSCLC may potentially be sensitized radiation treatment by reducing those factors that continuously enhance the of damaged DNA. In present study, normal fibroblast MRC‑5 and A549 cells were treated with NU7026 CGK733, which are inhibitors DNA‑dependent protein kinase catalytic subunit (PKcs) ataxia telangiectasia mutated (ATM) Rad3‑related (ATR), respectively, followed...
Heath-related quality of life (HRQoL) among survivors with unresectable locally-advanced non-small cell lung cancer (LA-NSCLC) treated radiotherapy and chemotherapy still is not clear. The current study were performed to determine HRQoL for long-term LA-NSCLC identify risk factors poor HRQoL. Among patients receiving between January 2006 December 2010, 82 beyond 5 years identified in this cross-sectional study. European Organization Research Treatment Cancer Quality Life Questionnaire (EORTC...
Abstract Background: The decreased level of miR-192-5p has been reported in several kinds cancers, including bladder, colon, ovarian, and non-small cell lung cancer. However, the expression function papillary thyroid carcinoma/cancer (PTC) remains unknown. Objective: present study aimed to explore underlying mechanism PTC development. Methods: tissues relative normal controls from patients were collected. qRT-PCR analysis was performed measure SH3RF3 mRNA lines. CCK-8 method FCM assay used...
Background: Radiation is a mode of treatment for many pelvic malignancies, most which originate in the gynecologic, gastrointestinal, and genitourinary systems. However, healthy gut unavoidably included irradiation volume, resulting undesirable results that manifest as radiation-induced diarrhea (RID), common side effect radiation therapy significantly affects patients' quality life. This study aimed to investigate potential mechanism after radiotherapy rats based on bile acid homeostasis...
Abstract In radiotherapy, air-filled ion chamber detectors are ubiquitously used in routine dose measurements for treatment planning. However, its use has been restricted by intrinsic low spatial resolution barriers. We developed one procedure patient-specific quality assurance (QA) arc radiotherapy coalescing two adjacent measurement images into a single image to improve and sampling frequency, investigated how different resolutions affect the QA results. PTW 729 1500 were dosimetric...
Glioma is a prevalent primary brain cancer with high invasiveness and typical local diffuse infiltration. Alternative splicing (AS), as pervasive transcriptional regulatory mechanism, amplifies the coding capacity of genome promotes progression malignancies. This study was aimed at identifying AS events novel biomarkers associated survival for glioma.RNA patterns were collected from The Cancer Genome Atlas SpliceSeq database, followed by calculating percentage index. Expression profiles...
Abstract BACKGROUND The STUPP regimen, which consists of postoperative radiotherapy with concurrent temozolomide (TMZ) followed by up to six cycles adjuvant TMZ chemotherapy, is the established standard treatment for newly diagnosed glioblastoma (GBM). However, its effectiveness limited. Anlotinib, a multi-kinase inhibitor targeting tumor angiogenesis and cell proliferation, has demonstrated promising results in preclinical GBM models phase I clinical trials. In order assess efficacy safety...
Objective: The aim of this retrospective study was to evaluate the prognostic significance pretreatment Neutrophil-to-Lymphocyte Ratio(NLR) in locally advanced non-small cell lung cancer(NSCLC) patients treated with thoracic radiotherapy. Methods: We retrospectively analyze 420 who received radiotherapy alone, sequential chemoraiotherapy or concurrent chemoradiotherapy for stage NSCLC from January 2007 December 2010 our hospital. were divided into two groups (high NLR group and low group)...
Abstract Background The prognosis of gastric cancer remains poor. Pyroptosis-related genes (PRGs) have been investigated as a potential biomarker in several types cancer, including cancer. This study aimed to investigate the expression, mutation and diagnostic prognostic value PRGs, analyzing data from Cancer Genome Atlas (TCGA) Gene Expression Omnibus (GEO) databases. Methods RNA-sequencing (RNA-seq), somatic datasets, copy number variation (CNV) for were also collected TCGA. expression...