A5033828754- Advanced Drug Delivery Systems
- Advancements in Transdermal Drug Delivery
- Inhalation and Respiratory Drug Delivery
- Nanoparticle-Based Drug Delivery
- Lipid Membrane Structure and Behavior
- Drug Solubulity and Delivery Systems
- biodegradable polymer synthesis and properties
- Pancreatic function and diabetes
- Microencapsulation and Drying Processes
- Analytical Chemistry and Chromatography
- Cannabis and Cannabinoid Research
- RNA Interference and Gene Delivery
- Nanoparticles: synthesis and applications
- Surfactants and Colloidal Systems
- Diabetes Management and Research
- Food Chemistry and Fat Analysis
- Proteins in Food Systems
- Pharmaceutical Practices and Patient Outcomes
- Tissue Engineering and Regenerative Medicine
- Layered Double Hydroxides Synthesis and Applications
- Synthesis and properties of polymers
- Pharmaceutical studies and practices
- Esophageal and GI Pathology
- Electrospun Nanofibers in Biomedical Applications
- Bioactive Compounds and Antitumor Agents
University of Bologna
2020-2025
Centro Nacional de Biotecnología
2025
Università di Camerino
2015-2020
University of Perugia
2007-2018
Azienda Ospedaliera S.Giuseppe Moscati
2012
University of Rome Tor Vergata
2002-2006
University of Florence
1987
Poly(glycolic acid), poly(lactic acid) and poly(lactic-co-glycolic were approved by the United States Food Drug Administration (FDA) in 1970s as materials for manufacturing of bioresorbable surgical sutures, but soon became reference preparation sustained release formulations, especially injectable microparticles. Since 1986 approval Decapeptyl® SR, first product based on PLGA microspheres, more than 15 such products have been clinical use. This article highlights key steps that brought to...
Critical micelle concentration (CMC) is the main chemical–physical parameter to be determined for pure surfactants their characterization in terms of surface activity and self-assembled aggregation. The CMC values can calculated from different techniques (e.g., tensiometry, conductivity, fluorescence spectroscopy), able follow variation a physical property with surfactant concentrations. Different mathematical approaches have been applied determination raw experimental data. Most them are...
Cocoa seed polyphenols have demonstrated interesting beneficial effects in humans. Most contained fresh seeds are chemically modified during fermentation, drying, and cocoa powder or chocolate production. The improvement of these procedures to obtain a high-polyphenol-content is highly desirable. To this aim, field investigation on the effect fermentation natural drying fine flavor National (cacao Nacional) was performed. were fermented for 6 days and, every day, samples sun-dried analyzed...
Nanostructured lipid carriers (NLC) loaded with palmitoylethanolamide (PEA) were formulated the aim to enhance ocular bioavailability of PEA, particularly back eye. Technological characterization (e.g. size, charge) NLC PEA formulation (PEA-NLC) was performed, and morphology characterized by electron microscopy. Ocular pharmacokinetic study, after topical administration formulation, carried out in rabbit Ultra-high performance liquid chromatography tandem mass spectrometry analysis detect...
Cancer remains one of the most important challenges in biomedical sciences. Chemotherapeutic agents are very potent molecules that exhibit a significant level toxicity numerous tissues body, particularly those characterized by high proliferative activity, such as bone marrow. The scenario is even more complex case central nervous system, and particular brain tumors, where blood barrier limits efficacy drug therapies. Integrins, transmembrane proteins widely expressed different types cancer...