A5008508856- Animal Nutrition and Physiology
- Biochemical Analysis and Sensing Techniques
- Reproductive Biology and Fertility
- Sperm and Testicular Function
- Olfactory and Sensory Function Studies
- Regulation of Appetite and Obesity
- Thyroid Disorders and Treatments
- Lipid metabolism and disorders
- Barrier Structure and Function Studies
- Reproductive Physiology in Livestock
- Biochemical effects in animals
- Cell death mechanisms and regulation
- Reproductive System and Pregnancy
- Growth Hormone and Insulin-like Growth Factors
- Nitric Oxide and Endothelin Effects
- Hormonal Regulation and Hypertension
- Selenium in Biological Systems
- Gut microbiota and health
- Ovarian function and disorders
- Hormonal and reproductive studies
- Estrogen and related hormone effects
- Pregnancy and preeclampsia studies
- Folate and B Vitamins Research
- Cancer-related molecular mechanisms research
- Birth, Development, and Health
Nanjing Agricultural University
2016-2025
University of Massachusetts Chan Medical School
2021
Premature ovarian failure (POF) is one of the principal causes female infertility, and although its are complex diverse, autoimmune deficiency may be involved. Human umbilical cord mesenchymal stem cells (UCMSCs) can used for tissue regeneration repair. Therefore, present study was designed to determine role UCMSCs in immune factor-induced POF rats. In this study, different concentrations were injected into induced Ovarian functions examined by evaluating estrus cycle, follicular morphology,...
Abstract Polycystic ovary syndrome (PCOS) is the leading cause of anovulatory infertility. Inadequate understanding ovulation drivers hinders PCOS intervention. Herein, we report that follicle stimulating hormone (FSH) controls follicular fluid (FF) glutamine levels to determine ovulation. Murine starts from FF-exposing granulosa cell (GC) apoptosis. FF glutamine, which decreases in pre-ovulation porcine FF, elevates patients FF. High-glutamine chow elevate inhibits mouse GC apoptosis and...
This study explores the effects of fermented bamboo powder (FBP) on growth performance, antioxidant status, intestinal morphology, and expression nutrient transporter genes in broiler chickens. Two groups were formed from 600 healthy 1-day-old chicks; each group included 30 chicks, repeated 10 times. The control was fed a basal diet supplemented experimental group’s with 1.0 g/kg FBP during phase I (days 1–22) 2.0 II 23–45). findings revealed significant enhancement performance for that...
Thyroid hormones and oxidative stress play significant roles in the normal functioning of female reproductive system. Nitric oxide (NO), a free radical synthesized by nitric synthases (NOS), participates regulation thyroid function is also good biomarker for assessment status. Therefore, purpose this study was to investigate effects on uterine antioxidative status young adult rats. Thirty immature Sprague-Dawley rats were randomly divided into three groups: control, hypothyroid (hypo-T)...
The present study investigated the effects of fermented bamboo powder (FPB) on gut odorant receptors (OR), intestinal health, and growth performance dwarf yellow-feathered broiler chickens. Six hundred (600) healthy 1-day-old chicks were randomly assigned into 2 groups, with 10 replicates consisting 30 each. control group was fed a basal diet. In contrast, experimental diet supplemented 1.0, 2.0, 4.0, 6.0 g/kg FBP for 4 different phases, namely phase I (1-22 d), II (23-45 III (46-60 IV...
Our previous study showed that dietary stevioside supplementation could alleviate intestinal mucosal damage induced by lipopolysaccharide (LPS) through its anti-inflammatory and antioxidant effects in broiler chickens. However, it remains unknown whether feeding to breeder hens exert similar biological functions their offspring. The present aimed investigate maternal prevent LPS-induced alteration of gut microbiota chicken A total 120 Jinmao yellow-feathered were fed a basal diet (CON) or...
Genistein is abundant in the corn-soybean meal feed. Little information available about effect of dietary genistein on intestinal transcriptome chicks, especially when suffering from injury. In this study, 180 one-day-old male ROSS 308 broiler chickens were randomly allocated to 3 groups, with 4 replicates (cages) 15 birds each. The treatments as follows: chicks received a basal diet (CON), and underwent lipopolysaccharide-challenge (LPS), or supplemented 40 mg/kg LPS-challenge (GEN). LPS...
Abstract Mulberry‐leaf flavonoids (MF), extracted from mulberry leaves, exert antioxidant and hypolipidemic effects. The purpose of this experimental study was to investigate the effects dietary MF on ovarian function liver lipid metabolism aged breeder hens. We used 270 (60‐weeks‐old) Qiling hens randomly assigned in 3 treatments with supplemental doses (0, 30, 60 mg/kg). results showed that significantly improved egg‐laying rate, followed by reduced feed conversion rate (FCR) ( p <...
The intestinal immune function of chickens is limited during the early growing stage. Maternal nutritional intervention has been suggested to affect innate immunity offspring. present study aimed investigate effects maternal stevioside supplementation on chicken A total 120 Jinmao yellow-feathered breeder hens were fed a basal diet or supplemented with 250 mg/kg for 5 weeks. During last week, 200 breeding eggs from each group collected incubation. After hatching, 80 male offspring (40 group)...
We evaluated immobilization stress and resveratrol supplementation in immature male mice at 30 days of age for 15 consecutive days. Fifty Swiss were divided into five groups (10 each): Controls, restraint (RS), + vehicle (RS V), RS 2 mg/kg, 20 mg/kg. determined results on the basis hematoxylin eosin (H&E), "Periodic acid-Schiff" staining, TUNEL assay. The indicated that significantly decreased body weight, testis water/food intake compared to control; while ameliorated these effects....
In brief The apoptosis of granulosa cells (GCs) is the main reason for porcine follicular atresia. This study provides a novel mechanism peroxynitrite anion-mediated GC and atresia in ovary. Abstract Granulosa play crucial role development follicles, their cell ovary major contributor to Here, we provide new by describing which anion (OONO – ) may cause death. We discovered that nitric oxide, oxidative stress level, OONO were positively correlated with atresia, was accompanied high...
The objective of this study was to investigate the impact Lycopene and L-Carnitine, individually or in combination, on various physiological molecular factors related intestinal health absorption ability Roosters, such as morphology, serum biochemical parameters, genes involved uptake, nutritional transport genes, tight junction genes. findings revealed that combination L-Carnitine supplementation had been found increase concentration levels TP ALB. Interestingly, relative mRNA expression...
Insulin-like growth factor 1 (IGF-1) and Akt [also known as protein kinase B (PKB)] proteins have been reported to exhibit gastroprotective effects by reducing water immersion restraint stress (WRS)-induced gastric mucosal cellular apoptosis. To confirm whether the IGF-1/PTEN/Akt/FoxO signaling pathway is effective in protecting against ulcers, our current study was conducted examine expression localization of IGF-1, phosphatase tensin homologue deleted on chromosome 10 (PTEN), O subfamily...
Abstract Thyroid hormones are important in the development and regulation of testes. This study was conducted to determine effects hyper‐ hypothyroidism on testicular prepubertal rats aged 20–70 days. Weaning male (20 days old) until day 70 age were randomly divided into four groups: control, hyperthyroid (hyper‐T), hypothyroid (hypo‐T) treated with thyroxine (T4) (hypo‐T+T4). The results indicated that thyroid caused a significant effect body testis weights, food water consumption. In...