A5036617650- Psoriasis: Treatment and Pathogenesis
- Whipple's Disease and Interleukins
- Immunodeficiency and Autoimmune Disorders
- Malaria Research and Control
- melanin and skin pigmentation
- Computational Drug Discovery Methods
- Antimicrobial Peptides and Activities
- Forensic and Genetic Research
- Animal Genetics and Reproduction
- Herpesvirus Infections and Treatments
- Eosinophilic Esophagitis
- Evolution and Genetic Dynamics
- Atherosclerosis and Cardiovascular Diseases
- Genetic diversity and population structure
- Digestive system and related health
- Genetic Associations and Epidemiology
- Sirtuins and Resveratrol in Medicine
- Inflammatory Bowel Disease
- Cancer-related gene regulation
- Urticaria and Related Conditions
- Forensic Anthropology and Bioarchaeology Studies
- Nutrition, Genetics, and Disease
- Bioinformatics and Genomic Networks
- Mosquito-borne diseases and control
- IL-33, ST2, and ILC Pathways
Benha University
2024
Helwan University
2023-2024
Bayan University
2020
PRG S&Tech (South Korea)
2020
University of Khartoum
2006-2020
Abstract Objectives Malaria infection is still known to be a worldwide public health problem, especially in tropical and sub-tropical African countries like Sudan. A pilot study conducted describe the trend of P. falciparum drug resistance markers 2017–2018 comparison CQ AS/SP eras The Pfcrt , Pfmdr-1 Pfdhfr Pfdhps genes were investigated. Data deposited by antimalarial network was consulted, molecular previously reported from Sudan analyzed. Results Drug analysis successfully done on 20...
Abstract Background: Vitiligo is an immune-mediated, chronic skin condition that affects both the innate and adaptive immune systems. Antimicrobial peptide overexpression one of its defining characteristics. Granulysin (GNLY), antimicrobial peptide, may play a role in pathogenesis various autoimmune diseases. Objectives: To estimate serum GNLY levels vitiligo patients to correlate those with severity activity disease. Materials Methods: This case-control study included 60 non-segmental...
Background: Vitiligo is a depigmenting skin condition due to the attenuation of melanin in affected area specific melanocyte loss. The pathophysiology vitiligo has been linked both mitochondrial malfunction and oxidative stress. Dynamin-related protein 1 (DRP1) regulator fission. Uncoupling Protein 2 (UCP2) an essential that regulates cellular energy metabolism. Objectives: This study aimed assess gene expression levels UCP2 DRP1 patients correlate those with activity severity disease....
Abstract Objectives IL - 17A G197A and 17F A7488G polymorphisms has been identified to be associated with the susceptibility many diseases. This study aimed investigate frequency distribution of IL-17A IL-17F among healthy Sudanese population. A descriptive cross-sectional hospital-based molecular conducted in different sites throughout Sudan. Two ml blood samples were collected from 717 participants. Demographic data medical history participants collected. Results Of participants, 355...
Abstract Background Malaria infection is still known to be a worldwide public health problem, especially in tropical and sub-tropical African countries like Sudan. The fight against malaria taking place due many factors. One of these factors the presence Plasmodium falciparum drug resistant parasites. This study aiming at studying P. resistance markers analyzing historical literature on Methods A descriptive cross-sectional healthcare-centers based conducted Khartoum state between December...
Abstract Objectives: IL-17A G197A and IL-17F A7488G polymorphisms has been identified to be associated with the susceptibility many diseases. This study aimed investigate frequency distribution of among healthy Sudanese population. A descriptive cross-sectional hospital-based molecular conducted in different sites throughout Sudan. Two ml blood samples were collected from 717 participants. Demographic data medical history participants collected. Results: Of participants, 355 (49.5%) males...
Background: Idiopathic nephrotic syndrome (INS) is the most frequent glomerular disease affecting children.Its pathogenesis not completely evident, it probably due to immunological disturbance that increases cytokines production and alters permeability.Interleukin 13 (IL-13) has been implicated in INS by changing permeability of basement membrane inducing proteinuria.Objective: To investigate association between rs20541 (R130Q) single nucleotide polymorphism (SNP) IL-13 gene, idiopathic...
Many SNPs in the Prothrombin gene were known to be of clinical significance and associated with variety states. Molecular composition F2 variants could help studying genotypic phenotypic relationship. We used computational methods analyze predict disease either due structural variation or expression dysregulation.F2 contain 2938 Homo sapiens, 202 missense, 5 nonsynonymous, 118 synonymous, 21 3'UTR 10 5'UTR. There two In three different alleles them disrupts miRNA binding site while third one...
Abstract Objectives IL-17A G197A and IL-17F A7488G polymorphisms has been identified to be associated with the susceptibility many diseases. This study aimed investigate frequency distribution of among healthy Sudanese population. A descriptive cross-sectional hospital-based molecular conducted in different sites throughout Sudan. Two ml blood samples were collected from 717 participants. Demographic data medical history participants collected. Results Of participants, 355 (49.5%) males 362...
Abstract Objectives: IL-17A G197A and IL-17F A7488G polymorphisms has been identified to be associated with the susceptibility many diseases. This study aimed investigate frequency distribution of among healthy Sudanese population. A descriptive cross-sectional hospital-based molecular conducted in different sites throughout Sudan. Two ml blood samples were collected from 717 participants. Demographic data medical history participants collected. Results: Of participants, 355 (49.5%) males...