A5032038703- Radiation Therapy and Dosimetry
- Advanced Radiotherapy Techniques
- Meningioma and schwannoma management
- Vascular Malformations Diagnosis and Treatment
- Childhood Cancer Survivors' Quality of Life
- Hepatocellular Carcinoma Treatment and Prognosis
- Neurological disorders and treatments
- Statistical Methods in Clinical Trials
- Liver Disease and Transplantation
- Vascular Malformations and Hemangiomas
- Genetic and Kidney Cyst Diseases
- Viral gastroenteritis research and epidemiology
- Central Venous Catheters and Hemodialysis
- Medical Imaging Techniques and Applications
- Child and Adolescent Health
- Neurofibromatosis and Schwannoma Cases
- Anesthesia and Sedative Agents
- Diabetes and associated disorders
- Genomics and Rare Diseases
- Radiation Detection and Scintillator Technologies
- Hepatitis Viruses Studies and Epidemiology
- Adolescent and Pediatric Healthcare
- Venous Thromboembolism Diagnosis and Management
Wellcome / EPSRC Centre for Interventional and Surgical Sciences
2019-2022
University College London
2019-2022
King's College London
2019-2022
German Cancer Research Center
2017
Heidelberg University
2017
Heidelberger Institut für Radioonkologie
2017
Aarhus Municipality
1970
We report on the development of open-source cross-platform radiation treatment planning toolkit matRad and its comparison against validated systems. The enables three-dimensional intensity-modulated therapy for photons, scanned protons carbon ions.matRad is entirely written in Matlab freely available online. It re-implements well-established algorithms employing a modular sequential software design to model entire workflow. comprises core functionalities import DICOM data, calculate optimize...
Purpose: To investigate the influence of changes in α/β ratio (range 1.5-3 Gy) on iso-effective doses, with varying treatment time, spinal cord and central nervous system tissues comparable radio-sensitivity. It is important to establish if an 2 Gy, accepted norm for neuro-oncology iso-effect estimations, can be used.Methods: The rat irradiation data Pop et al. provided ED50 values radiation myelopathy times that varied from minutes ∼6 days. Analysis using biphasic repair kinetics, allowing...
Two cases of hepatic hemangiomas are described diagnosed by angiography and controlled repeat after 2.5 6 years, respectively. The radiologic appearance is although it varies, must be considered the safest method diagnosis; biopsy contraindicated. Steroid therapy seems to a possible mode treatment.
Objective.Dose-rate effects in Gamma Knife radiosurgery treatments can lead to varying biologically effective dose (BED) levels for the same physical dose. The non-convex BED model depends on delivery sequence and creates a non-trivial treatment planning problem. We investigate feasibility of employing inverse methods generate plans exhibiting desirable characteristics using per iso-centre beam-on times sequence.Approach.We implement two dedicated optimisation algorithms. One approach relies...