A5103033960- Cardiovascular Health and Disease Prevention
- Lipoproteins and Cardiovascular Health
- Mitochondrial Function and Pathology
- Peripheral Artery Disease Management
- Blood Pressure and Hypertension Studies
- Advanced biosensing and bioanalysis techniques
- Nitric Oxide and Endothelin Effects
- Cholesterol and Lipid Metabolism
- Stroke Rehabilitation and Recovery
- RNA Interference and Gene Delivery
- Plant biochemistry and biosynthesis
- Metabolism and Genetic Disorders
- Genomic variations and chromosomal abnormalities
- Pharmacology and Obesity Treatment
- Biochemical Acid Research Studies
- Cardiac Health and Mental Health
- Genetic Syndromes and Imprinting
- Molecular Biology Techniques and Applications
- Biosensors and Analytical Detection
- Diabetes, Cardiovascular Risks, and Lipoproteins
- DNA and Nucleic Acid Chemistry
- Cerebrovascular and Carotid Artery Diseases
- Muscle Physiology and Disorders
Sekisui Medical (Japan)
2023
Nihon University
2015
Tokyo Women's Medical University
2010
Nagoya University
2004-2009
OBJECTIVES: To assess the efficacy of various vascular endocrinological substances, such as plasma nitric oxide metabolites (NOx), surrogate markers survival in older patients. DESIGN: Prospective cohort, observational. SETTING: Nagoya University Hospital and related hospitals, Japan. PARTICIPANTS: One hundred fifty patients aged 70 older, recruited consecutively from outpatient clinics hospitals. MEASUREMENT: Serum biochemical analyses albumin total cholesterol, prognostic markers, tumor...
We describe a novel technology for detecting nucleic acids: Probe Alteration Link Self-Assembly Reactions (PALSAR). PALSAR comprises DNA self-assembly of pairs short probes formed by alternate hybridization three complementary regions in pair honeycomb (HCPs). Self-assembly occurs at designated salt concentrations and reaction temperatures requires no enzymes. prepared HCPs to detect mRNAs encoded the GAPDH gene β-actin (BA) gene, CD3D CD4 major vault protein (MV) signalling lymphocytic...
Quantitative bioanalysis is essential when establishing pharmacokinetic properties during the drug development process. To overcome challenges of sensitivity, specificity and process complexity associated with conventional analysis antisense oligonucleotides (ASOs), a new approach to nonenzymatic hybridization assays using probe alteration-linked self-assembly reaction (PALSAR) technology as signal amplifier was evaluated. PALSAR quantification ASOs in mouse tissue plasma able achieve high...
It is widely believed that evolutionarily advanced cells require nuclei rich in DNA to proliferate, while mitochondria isolated from cannot proliferate.We have developed a novel stable cell line, designated "mitochondrial (MitoCells)", maintaining active mitochondria, the majority of which lacked nuclei.MitoCells can be continuously generated culture.Herein, we report proliferation studies MitoCells.We found nuclear DNA-less (nDNA-less) MitoCells, were sorted with flow cytometry and...