A5082637516- Venous Thromboembolism Diagnosis and Management
- Atrial Fibrillation Management and Outcomes
- Acute Myocardial Infarction Research
- Antiplatelet Therapy and Cardiovascular Diseases
- Case Reports on Hematomas
- Blood Pressure and Hypertension Studies
- Heparin-Induced Thrombocytopenia and Thrombosis
- Blood Coagulation and Thrombosis Mechanisms
- Acute Ischemic Stroke Management
- Pharmaceutical Practices and Patient Outcomes
- Intramuscular injections and effects
- Clinical practice guidelines implementation
- Pharmacovigilance and Adverse Drug Reactions
- Patient Satisfaction in Healthcare
- Emergency and Acute Care Studies
- Cardiac Arrhythmias and Treatments
- Diagnosis and Treatment of Venous Diseases
- Healthcare cost, quality, practices
- Erythropoietin and Anemia Treatment
- Central Venous Catheters and Hemodialysis
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Iron Metabolism and Disorders
- Pharmaceutical studies and practices
- Cardiac electrophysiology and arrhythmias
- Sexuality, Behavior, and Technology
University of New Mexico Hospital
2014-2024
University of New Mexico
2015-2023
Venous thromboembolism (VTE) is the third most common vascular disease. Medical inpatients, long-term care residents, persons with minor injuries, and long-distance travelers are at increased risk.
Tens of millions patients worldwide use anticoagulant medications to prevent or treat thrombotic conditions, including atrial fibrillation and venous thromboembolism. With the introduction direct oral anticoagulants (DOACs) as preferred therapy over vitamin K antagonists (eg, warfarin), overall has increased markedly.1.Grymonprez M. Simoens C. Steurbaut S. De Backer T.L. Lahousse L. Worldwide trends in with from 2010 2018: a systematic review meta‐analysis.Europace. 2021;...
Abstract Multiple risk-assessment models (RAMs) for venous thromboembolism (VTE) in hospitalized medical patients have been developed. To inform the 2018 American Society of Hematology (ASH) guidelines on VTE, we conducted an overview systematic reviews to identify and summarize evidence related RAMs VTE bleeding inpatients. We searched Epistemonikos, Cochrane Database, Medline, Embase from 2005 through June 2017 then updated search January 2020 that included study selection, data...
Abstract Anticoagulation is a leading cause of medication‐related harm. As result, there increasing recognition the importance development anticoagulation stewardship programs to ensure safe and effective use across health care settings. Securing administrative leadership support build such necessary first step but often significant barrier implementation. Herein, we present structured approach guide providers advocating for at their institutions. We divide into four phases: (1) Build...
A quality-improvement program at University of New Mexico Hospital (UNMH) encompassing admission, discharge, and postdischarge medication reconciliation activities is described, with a report on initial assessments the program's impact rates medication-related problems (MRPs). Pharmacists conducted five-month evaluation UNMH Care Transitions Service (CTS), which serves inpatients admitted to hospital's family medicine service, providing targeted MRP interventions. Selected patients who...
This scoping review summarizes the extent and characteristics of published literature describing digital population management dashboards implemented to improve quality anticoagulant management. A standardized search protocol was executed identify relevant manuscripts between January 1, 2015 May 31, 2022. The resulting records were systematically evaluated by multiple blinded reviewers findings from selected papers summarized. Twelve identified, originating 5 organizations within US 2 other...
#### What you need to know An 83 year old woman is brought the emergency department by her care giver who noticed altered mental status following two episodes of passing black faeces. The has a history ischaemic stroke associated with atrial fibrillation and hypertension on dabigatran for prevention. She took last dose few hours ago. Computed tomography head shows no acute intracranial abnormalities. Abdominal rectal exams are normal. Her blood pressure 82/56 mm Hg. multidisciplinary team...
Anti-factor Xa values in morbidly obese patients receiving standard doses of fondaparinux sodium for the prevention venous thromboembolism (VTE) were analyzed a retrospective chart evaluation.The administration low-molecular-weight heparins to (body mass index [BMI] ≥30 kg/m(2)) at dose recommended VTE prophylaxis has been reported result increased thromboembolic events and decreased anti-factor levels, some evidence indicates that weight-based dosing adjustments may be appropriate. To study...
The aim of this study was to evaluate and describe the utilization safety 4F-PCC in a nonanticoagulated, nonsurgical patient population at an academic, tertiary care center. This retrospective, single-center chart review evaluated nonanticoagulated adult patients least 18 years age who had one dose administered between January 1, 2017, September 30, 2022, for indication. Hemostatic efficacy following administration primary outcome, secondary outcomes included assessment blood product...
The case of a patient with confirmed heparin-induced thrombocytopenia (HIT) and anticoagulation failure undergoing catheter-directed thrombolysis (CDT) alteplase bivalirudin for extensive thrombosis is reported.A 48-year-old, morbidly obese Caucasian woman was admitted to trauma-surgical intensive care unit (TSICU) after motor vehicle accident. suffered aortic renal lacerations, multiple rib spinal fractures, pleural effusion, bilateral subdural hematomas, cerebral edema. An inferior vena...
Background: Venous thromboembolism (VTE) is a major health problem and common cause of morbidity mortality in hospitalized patients. While trials both surgical medically ill patients have demonstrated efficacy safety enoxaparin for VTE prophylaxis (VTEP), they failed to adequately represent morbidly obese (body mass index > 40 kg/m 2 ) Objective: To assess the impact weight-adjusted dosing algorithm on anti–factor Xa levels, thrombosis, bleeding Methods: A retrospective chart review was...
Background: No randomized controlled trials have investigated enoxaparin once versus twice daily for venous thromboembolism (VTE) treatment in cancer patients. Objective: To compare the safety and efficacy of 1 mg/kg 1.5 mg/kg/day acute VTE Methods: This was a single-center, retrospective, observational cohort study. Adults with active an were included. The primary outcome evaluated incidence clinically relevant (major nonmajor) bleeding (CRB) within 30 days initiation. Secondary outcomes...
Abstract Background Over 6 million people in the United States require anticoagulation. Current guidelines recommend direct oral anticoagulants (DOACs) over warfarin for select indications due to increased safety and similar efficacy. However, data suggest DOAC conversion occurs less than 5% of patients. Objectives To assess rates from DOACs rate inpatient pharmacist assessment conversions using an evidence‐based checklist. Methods In this retrospective cohort study, all patients ≥18 years...