A5017060426- Venous Thromboembolism Diagnosis and Management
- Atrial Fibrillation Management and Outcomes
- Antiplatelet Therapy and Cardiovascular Diseases
- Acute Ischemic Stroke Management
- Health Systems, Economic Evaluations, Quality of Life
- Cardiac Arrhythmias and Treatments
- Blood Pressure and Hypertension Studies
- Acute Myocardial Infarction Research
- Pharmaceutical Practices and Patient Outcomes
- COVID-19 Clinical Research Studies
- Health Policy Implementation Science
- Central Venous Catheters and Hemodialysis
- COVID-19 and healthcare impacts
- Healthcare Systems and Technology
- Diagnosis and Treatment of Venous Diseases
- Clinical practice guidelines implementation
- Smoking Behavior and Cessation
- Heart Failure Treatment and Management
- Cardiac electrophysiology and arrhythmias
- Patient Satisfaction in Healthcare
- Primary Care and Health Outcomes
- Blood Coagulation and Thrombosis Mechanisms
- Gastrointestinal Bleeding Diagnosis and Treatment
- Cardiac Health and Mental Health
- Healthcare cost, quality, practices
University of Michigan
2016-2025
Michigan Medicine
2016-2025
Michigan United
2018-2024
University of Utah
2024
University Health Network
2024
St. Michael's Hospital
2024
University of Toronto
2024
Quality Enhancement Research Initiative
2019-2024
Georgetown University
2024
VA Center for Clinical Management Research
2015-2024
Coronavirus disease 2019 (COVID-19) is a viral infection that can, in severe cases, result cytokine storm, systemic inflammatory response and coagulopathy prognostic of poor outcomes. While some, but not all, laboratory findings appear similar to sepsis-associated disseminated intravascular (DIC), COVID-19- induced (CIC) appears be more prothrombotic than hemorrhagic. It has been postulated CIC may an uncontrolled immunothrombotic COVID-19, there growing evidence venous arterial...
Despite guideline recommendations to use low-molecular-weight heparins (LMWHs) or direct oral anticoagulants in the treatment of most patients with acute pulmonary embolism (PE), US-based studies have found increasing unfractionated heparin (UFH) hospitalized patients.
<h3>Importance</h3> Patient failure to disclose medically relevant information clinicians can undermine patient care or even lead harm. <h3>Objective</h3> To examine the frequency of patients failing their that is and reasons for doing so. <h3>Design, Setting, Participants</h3> Two national nonprobability samples were recruited participate in an online survey, one using Amazon's Mechanical Turk (MTurk) from March 16 30, 2015 (2096 respondents), followed by Survey Sampling International (SSI)...
<h3>Importance</h3> Venous thromboembolism (VTE) is a common complication of COVID-19. It not well understood how hospitals have managed VTE prevention and the effect strategies on mortality. <h3>Objective</h3> To characterize frequency, variation across hospitals, change over time in prophylaxis treatment-dose anticoagulation patients hospitalized for COVID-19, as association with in-hospital 60-day <h3>Design, Setting, Participants</h3> This cohort study adults COVID-19 used pseudorandom...
Abstract Thromboembolism is a common and deadly consequence of COVID-19 infection for hospitalized patients. Based on clinical evidence pre-dating the pandemic early observational reports, expert consensus guidance documents have strongly encouraged use prophylactic anticoagulation patients infection. More recently, multiple trials larger studies provided tailoring approach to thromboprophylaxis with COVID-19. This document provides updated anticoagulant therapies in from Anticoagulation...
Abstract Objective To evaluate the effectiveness of multiple decision aid strategies in promoting high quality shared making for prevention stroke patients with non-valvular atrial fibrillation. Design Cluster randomized controlled trial. Setting Six academic medical centers United States. Participants Patient participants were aged ≥18 a diagnosis fibrillation, at risk (CHA 2 DS -VASc ≥1 men, ≥2 women), and scheduled clinical appointment to discuss strategies. Participating clinicians those...
Anticoagulation clinics were initially developed to provide safe and effective care for warfarin-treated patients with atrial fibrillation, venous thromboembolism, mechanical valve replacement. Traditionally, these required ongoing laboratory monitoring warfarin dose adjustment by expert providers. With the introduction of direct oral anticoagulants (dabigatran, rivaroxaban, apixaban, edoxaban), many have questioned need anticoagulation clinic. However, we think that growing number...
Background We provide the first multicenter analysis of patients cared for by eight Pulmonary Embolism Response Teams (PERTs) in United States (US); describing frequency team activation, patient characteristics, pulmonary embolism (PE) severity, treatments delivered, and outcomes. Methods enrolled from National PERT Consortium™ registry with a activation between 18 October 2016 17 2017. Data are presented combined institution. Differences institutions were analyzed using chi‐squared test or...
It is unclear how many patients treated with a direct oral anticoagulant (DOAC) are using concomitant acetylsalicylic acid (ASA, or aspirin) and this affects clinical outcomes.To evaluate the frequency outcomes of prescription ASA DOAC therapy for atrial fibrillation (AF) venous thromboembolic disease (VTE).This registry-based cohort study took place at 4 anticoagulation clinics in Michigan from January 2015 to December 2019. Eligible participants were adults undergoing treatment AF VTE,...
Tens of millions patients worldwide use anticoagulant medications to prevent or treat thrombotic conditions, including atrial fibrillation and venous thromboembolism. With the introduction direct oral anticoagulants (DOACs) as preferred therapy over vitamin K antagonists (eg, warfarin), overall has increased markedly.1.Grymonprez M. Simoens C. Steurbaut S. De Backer T.L. Lahousse L. Worldwide trends in with from 2010 2018: a systematic review meta‐analysis.Europace. 2021;...
Summary Pulmonary embolism (PE) is a major cause of morbidity and mortality world-wide, the use thrombolytic therapy has been associated with favourable clinical outcomes in certain patient subsets. These potential benefits are counterbalanced by risk bleeding complications, most devastating which intracranial haemorrhage (ICH). We retrospectively evaluated 9703 patients from 2003–2012 nationwide in-patient sample database (NIS) who received thrombolytics for PE. All ICH during PE...