A5081632927- Advanced Fluorescence Microscopy Techniques
- Point processes and geometric inequalities
- Cell Image Analysis Techniques
- Image and Signal Denoising Methods
- Morphological variations and asymmetry
- Photoacoustic and Ultrasonic Imaging
- Handwritten Text Recognition Techniques
- Acoustic Wave Resonator Technologies
- Spectroscopy and Chemometric Analyses
- Advanced Biosensing Techniques and Applications
- Image Processing Techniques and Applications
- Antenna Design and Optimization
- Diffusion and Search Dynamics
- Advanced Electron Microscopy Techniques and Applications
- Natural Language Processing Techniques
- Electromagnetic Scattering and Analysis
- Statistical Methods and Inference
- Antenna Design and Analysis
- Vehicle License Plate Recognition
- Sensor Technology and Measurement Systems
- Statistical and numerical algorithms
- Complex Systems and Time Series Analysis
- Single-cell and spatial transcriptomics
- Advanced MEMS and NEMS Technologies
- Soil Geostatistics and Mapping
Imperial College London
2016-2025
Cornell University
2025
Weill Cornell Medicine
2025
The London College
2019
Arcon (United States)
1980-2016
The University of Texas at Dallas
2012-2013
The University of Texas Southwestern Medical Center
2012
University at Buffalo, State University of New York
1976-2003
Buffalo State University
1976-1992
Roswell Park Comprehensive Cancer Center
1976
The outer membrane (OM) of gram-negative bacteria is a robust, impermeable barrier that excludes many classes antibiotics. Contrary to the classical model an asymmetric lipid bilayer, recent evidence suggests OM predominantly proteolipid (APLM). Outer leaflet lipopolysaccharides (LPS) surround integral β-barrel proteins (OMPs) are shared with other OMPs form supramolecular network in which levels approach those LPS. Some most abundant Escherichia coli trimeric porins. How porins and LPS...
The use of the wavelet coherence two series in hypothesis testing relies on some sort smoothing being carried out order that estimator is not simply unity. A previous study considered averaging via multiple Morse wavelets. Here we consider time-domain and a single Morlet wavelet. Since complex-valued, derive analytic results for case calculated from jointly stationary Gaussian time series. temporally smoothed can be written terms Welch's overlapping segment (WOSA) spectrum estimators, by...
Single-molecule localisation microscopy (SMLM) allows the of fluorophores with a precision 10-30 nm, revealing cell's nanoscale architecture at molecular level. Recently, SMLM has been extended to 3D, providing unique insight into cellular machinery. Although cluster analysis techniques have developed for 2D data sets, few applied 3D. This lack quantification tools can be explained by relative novelty imaging such as interferometric photo-activated (iPALM). Also, existing methods that could...
Hypertension is a leading cause of premature mortality in Tanzania, but low trust and awareness biomedical healthcare prioritization spiritual over physical health hinders uptake care. Religious leaders are highly respected community members eager to collaborate with professionals. Few worker training programs utilize evidence-based pedagogical recommendations combination theology specific their students' backgrounds. Our team research professionals religious developed curriculum teach local...
The use of statistical thinning and quantized element weights to produce low sidelobe patterns using large circular array apertures is investigated. major results the analysis show that by either several algorithms it possible obtain substantial reduction a combination discrete amplitude quantization. paper includes generalized formulas for level, EIRP (effective isotropic radiated power), curves how these parameters vary as function design level selected Taylor pattern.< <ETX...
Fluorescing molecules (fluorophores) that stochastically switch between photon-emitting and dark states underpin some of the most celebrated advancements in super-resolution microscopy. While this stochastic behavior has been heavily exploited, full characterization underlying models can potentially drive forward further imaging methodologies. Under assumption fluorophores move fluorescing as continuous time Markov processes, goal is to use a sequence images select model estimate transition...
Understanding a block of handwritten text means mapping it into semantic representation. We describe an approach to reading when there are certain loose constraints placed on the spatial layout and syntax text. Early recognition primitives guides location syntactic components. A system read postal addresses is described as instance. The representation in this case digit string (ZIP Code). Methods for segmenting digits components recognizing using multiplicity recognizers given.
Abstract The resolution of an imaging system is a key property that, despite many advances in optical methods, remains difficult to define and apply. Rayleigh’s Abbe’s criteria were developed for observations with the human eye. However, modern data typically acquired on highly sensitive cameras often requires complex image processing algorithms analyze. Currently, no approaches are available evaluating resolving capability such that now central analysis data, particularly location-based...
Structured Illumination Microscopy (SIM) is a widespread methodology to image live and fixed biological structures smaller than the diffraction limits of conventional optical microscopy. Using recent advances in up-scaling through deep learning models, we demonstrate method reconstruct 3D SIM stacks with twice axial resolution attainable reconstructions. We further our robust noise evaluate it against two-point cases gratings. Finally, discuss potential adaptions improve resolution. This...
Describes the control structure for an intelligent handwritten address interpretation system. The system takes a grey-level image, segments into lines and words, parses meaningful syntactic categories, recognizes words using dynamically generated lexicons, determines destination code with aid of postal directories.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
This paper reviews some of the motivation that has led to development SAW bandpass filters, based on withdrawal-weighted designs. A computer-aided procedure for synthesis such filter described. Using a spectral-weighting transducer model which is valid at fundamental and harmonic frequencies, examples filters designed with computer are presented.
A key difficulty that arises from real event data is imprecision in the recording of time-stamps. In many cases, retaining times with a high precision expensive due to sheer volume activity. Combined practical limits on accuracy measurements, binned common. order use point processes model such data, tools for handling parameter estimation are essential. Here we consider Hawkes process, type self-exciting process has found application modeling financial stock markets, earthquakes and social...
A methodology for recognizing ZIP codes (US postal codes) in handwritten addresses is presented that uses many diverse pattern recognition and image processing algorithms. Given a high-resolution of address block, the solution invokes routines capable hypothesizing location code, segmenting code digits, locating city state names, looking up results dictionary. The control structure not strictly sequential, but rather form blackboard architecture opportunistically as needed. An implementation...
Wavelet coherence computed from two time series has been widely applied in hypothesis testing situations, but proven resistant to analytic study, with resort simulations for statistical properties. As part of the null being tested, such invariably assume joint stationarity series. If estimated using multiple orthogonal Morse wavelets, wavelet is fact amenable study. Since wavelets are complex-valued, we consider case calculated discrete-time complex-valued and stationary Under Gaussianity,...
A previous study considered the estimation of wavelet coherence from jointly stationary time series via time-domain smoothing and use a single Morlet wavelet. The form asymptotic (Goodman's) distribution was derived. In this paper we extend approach to nonstationary where nonstationarity is induced by various types modulation. model forms studied include constant over scale, time-varying, scale-varying, time-and-scale varying. These models are carefully derived appropriate statistical for...
The characterization and comparison of various interdigital transducer (IDT) models used to analyze design SAW transversal filters are facilitated by partitioning the overall periodic re- sponse into an impulse function, a discrete time sampling m acoustic weighting function in order describe both wide-band space harmonic responses. Through this formalism analog char- acter IDT is accounted for use a(f). This perspective applied five models: namely, (equivalent circuit), (sine wave),...
We present an asymptotic treatment of errors involved in point-based image registration where control point (CP) localization is subject to heteroscedastic noise; a suitable model for fluorescence microscopy. Assuming affine transform, CPs are used solve multivariate regression problem. With measurement existing both sets this errors-in-variable problem and linear least squares inappropriate; the correct method being generalized squares. To allow dependent equivalence maximum likelihood...
Evolutionary spectra were developed by Priestley to extend spectral analysis some nonstationary time series, in particular semistationary processes, of which the ubiquitous uniformly modulated processes are a subclass. Coherence is well defined for bivariate and can be estimated from such processes. We consider Priestley's estimator evolutionary density matrix, show that its elements written as weighted multitaper estimators with calculable weights tapers. Under Gaussianity an approximating...